Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and/or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and/or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain.

A music sync low frequency stimulator can includes a speaker for outputting a plurality of first sound source signals, a sound source signal separator for separating at least one of the plurality of first sound source signals, a low frequency signal generator for generating a low frequency signal, and a music sync unit for controlling the strength and frequency of a low frequency signal according to at least one of second sound source signals separated by the sound source signal separator.

The present invention relates to an auricular neurostimulation device wearable by a user and configured to stimulate the Auricular Branch of Vagus Nerve (ABVN) on the user’s ear: the device comprises at least two electrodes designed to be located in the cymba and in the cavity of the cavum conchae respectively; the electrodes stimulate the nerve ramifications of the cymba and the cavum conchae, respectively, when an electrical voltage difference is applied between them. The invention further refers to an auricular neurostimulation system comprising an auricular neurostimulation device as described and a charging case where the device can charge an internal battery and where the device discharges into this case the data captured by the photoplethysmographic or biosensor during stimulation and sends them to a dedicated platform in the cloud. The invention also refers to a method of operation of an auricular neurostimulation system as described.

Provided are stimulation devices for improving ambulatory activity of a subject in need thereof. The device includes a foot covering for holding two battery-operated tactile actuators on a metatarsal region and an ankle region of the wearer's foot. The foot covering also includes a detachable material for housing and securing the two tactile actuators and a pouch region for holding electronics.

The present disclosure relates to a method for increasing an amount of air and/or oxygen passing through an airway of an individual, reducing airway restrictions in an individual, increasing airway patency and/or maintaining airway patency in an individual, decreasing snoring, obstructive sleep apnea, or a combination thereof, in an individual. The method may comprise stimulating at least four regions of the individual's neck, where two of the at least four regions of the individual's neck are anterior triangle regions on opposing sides of the individual's midline, and another two of the at least four regions of the individual's neck are anterior triangle regions on opposing sides of the individual's midline, posterior to the two of the at least four regions. The present disclosure also discusses related devices and systems.

A telekinetic bionic glove assembly having a glove assembly, first and second boxes attached to the glove assembly, an arm box, and an electrical lead assembly connected to the arm box. The glove assembly has string guides positioned on glove fingers. The glove assembly also has a main bar and bands positioned at a glove back face, and a thumb splint. The first box has strings, motors, a motor controller, and reels. The second box has a voltage regulator, a battery, and a computer. The arm box has an arm box computer, an arm box voltage regulator, a bio-signal amplifier, an arm box battery, and arm box switch. The electrical lead assembly has electrical leads, lead heads, electrodes, and adhesive pads. The glove assembly operates, whereby the glove fingers open and close in response to voltage spikes as results of eye movements.

Devices, systems and methods for treating various disorders and medical conditions through noninvasive stimulation of a nerve. A system comprises a stimulator including an electrode configured to contact an outer skin surface of a patient and an energy source coupled to the housing, The energy source generates an electrical impulse and the stimulator transmits the electrical impulse from the electrode transcutaneously through an outer skin surface of the patient to a selected nerve within the patient. The system further includes an application on a mobile device that receives data from a remote source. The mobile device couples to the stimulator and the application causes the mobile device to transmit the data to the stimulator.

A therapeutic device for cell stimulation or cell therapy comprises a housing which contains an electrode, a generator for generating high-frequency pulses, a processor unit comprising a control, regulation and calculation module, a memory unit, a control element, a controllable modulator, by means of which the generator can be controlled. A voltage pulse sequence comprising a plurality of voltage pulses can be generated by means of the modulator, wherein the frequency of the voltage pulse sequence can be at least partially not constant.

A vestibular neurostimulation device, which may include first and second electrodes; first and second thermoelectric devices thermally coupled, respectively, to first and second earpieces that are configured to be insertable into respective ear canals of a patient; and a controller comprising a waveform generator. The waveform generator may be is configured to deliver a modulated electric signal to the patient through galvanic vestibular stimulation (GVS) using the first and second electrodes and to deliver a time varying thermal waveform to the patient through caloric vestibular stimulation (CVS) using the first and second earpieces simultaneous with the delivery of the modulated electrical signal through GVS. The CVS and/or GVS may be configured to increase a passage of insulin-like growth factor 1 (IGF-1) through a blood-brain-barrier.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.