Systems and methods for monitoring physiologic response to Valsalva maneuver (VM) are disclosed. An exemplary patient monitor may detect a natural incidence of a VM session occurred in an ambulatory setting using a heart sound (HS) signal sensed from the patient. The patient monitor may include a physiologic response analyzer to sense patient physiologic response during the detected VM session, and generate a cardiovascular or autonomic function indicator based on the sensed physiologic response to the VM. Using the physiologic response to the VM, the system may detect a target physiologic event using the sensed physiologic response to the VM.

A medical device is configured to receive cardiac electrical signals and sense ventricular event signals from the cardiac electrical signals. The medical device may start a validation window in response to sensing a ventricular event signal and determine if the ventricular event signal is a valid event signal or an invalid event signal based on processing of a different cardiac electrical signal than the cardiac electrical signal from which the ventricular event signal was sensed.

A medical device is configured to sense an electrical signal and determine that signal to noise criteria are met based on electrical signal segments stored in response to sensed electrophysiological events. The medical device is configured to determine an increased gain signal segment from one of the stored electrical signal segments in response to determining that the signal to noise criteria are met. The medical device determines a noise metric from the increased gain signal segment. The stored electrical signal segment associated with the increased gain signal segment may be classified as a noise segment in response to the noise metric meeting noise detection criteria.

A pacemaker system includes a drive-sense circuit (DSC) operably coupled to a pacemaker lead. The DSC generates a pace signal including electrical impulses based on a reference signal. The DSC provides the pace signal via the pacemaker lead to an electrically responsive portion of a cardiac conductive system of a subject to facilitate cardiac operation of a cardiovascular system of the subject. The DSC senses, via the pacemaker lead, cardiac electrical activity of the cardiovascular system of the subject that is generated in response to the pace signal and electrically coupled into the pacemaker lead and generates a digital signal that is representative of the cardiac electrical activity of the cardiovascular system of the subject that is sensed via the pacemaker lead. The DSC provides digital information to one or more processing modules that includes and/or is coupled to memory and that provide the reference signal to the DSC.

Implantable medical device configured to detect an atrial electric signal of a heart, and a ventricular electric signal of the same heart. Atrial events are evaluated in the atrial electric signal detected by a first detection unit and/or ventricular events are evaluated in the ventricular electric signal detected by a second detection unit for recognizing a condition of the device in which atrial electric signals are insufficiently detected.

Evaluation is done by applying at least one of: morphology of the detected atrial electric signals; lacking stability of atrial events; absence of atrial events over a period of time; an amplitude of the detected atrial electric signal being lower than a predefined threshold value; absence of atrial events during detection of ventricular electric signals simultaneously; comparison of atrial events sensed with first and second sensing profiles, the second being more sensitive than the first.

Systems and methods are described herein for evaluation and adjustment cardiac therapy. The systems and methods may initially evaluate a first pacing parameter while other pacing parameters are fixed to, for example, nominal values, and determine an effective setting for the first pacing parameter. Then, a second pacing parameter may be evaluated while the first pacing parameter is fixed to the previously-determined effective setting. Each evaluation may not test every possible setting for the pacing parameters, and instead, may utilize various processes to limit the settings to a subset of settings to test.

Some aspects relate to systems, devices, and methods of assessing heart rate recovery. A heart rate of a patient may be measured during a plurality of heart rate recovery events. Each of the plurality of heart rate recovery events comprises a duration of time after an activity resulting in an elevated heart rate. Heart rate recovery information may be determined based on the measured heart rate during each of the plurality of heart rate recovery events and a cardiac status of the patient may be generated from the determined heart rate recovery information over the plurality of heart rate recovery events.

Medical devices are provided, comprising a medical device and a sensor.

The present technology relates to intracardiac sensors and associated systems and methods. In some embodiments, the present technology includes a device for monitoring pressure within a patient's heart. The device can include an implantable capacitor having a capacitance value that is variable based on the pressure within the patient's heart and a sensing circuit configured to measure the capacitance value. The device can also include an implantable inductor and a power circuit configured to wirelessly receive power from an external source via the inductor. When the device is in a first configuration, the capacitor can be electrically coupled to the sensing circuit and the inductor can be electrically coupled to the power circuit. When the device is in a second configuration, the capacitor can be electrically coupled to the inductor to form a resonant circuit.

An impedance-monitoring method, applied to an electrical-stimulation device and a lead, is provided. The electrical-stimulation device stores a first impedance value of the electrical-stimulation device and a second impedance value of the lead. The method includes the following steps: utilizing the electrical-stimulation device to generate an electrical-stimulation signal, and to perform electrical stimulation on a target area using the electrical-stimulation signal; utilizing the electrical-stimulation device to sample the electrical-stimulation signal to calculate a total impedance value corresponding to the electrical-stimulation signal; and utilizing the electrical-stimulation device to calculate a tissue-impedance value according to the total impedance value, the first impedance value of the electrical-stimulation device, and the second impedance value of the lead. The tissue-impedance value is used to calculate the energy value of the electrical-stimulation signal transmitted to the target area.