An implantable device for harvesting in-vivo blood pressure fluctuations' energy to generate electrical power for powering medical implants while avoiding the need for external power sources.

This module comprises: a circuit for interfacing with the piezoelectric beam of an oscillating pendular unit, outputting a rectified signal comprising a sequence of pulses at a frequency equal to a multiple of the oscillation frequency of the pendular unit; a buffer capacitor charged by the successive pulses outputted by the interface circuit; and a converter regulator adapted to convert a capacitor discharge current into a stabilized power supply voltage, and controlled by a feedback control stage of the Maximum Power-Point Tracking (MPPT) type. A comparator detects the conduction of a blocking diode interposed between the interface circuit and the capacitor, in order to produce a signal representative of the current value of the duty cycle of the detected conduction and non-conduction periods. This signal is compared with a predetermined optimum duty cycle value in order to enable or disable the coupling of the capacitor to the converter regulator so as to control either the capacitor discharge towards an input of the converter regulator, or the continuation of its charging.

A system is presented for harvesting electromagnetic energy propagating in surroundings. The system comprises an antenna unit, a harvesting unit, and an input signal adapting circuit. The antenna unit is configured for receiving external electromagnetic radiation from the surroundings and producing a corresponding electric output. The harvesting unit comprises at least one energy harvesting circuit each configured and operable for receiving signals indicative of the output of the antenna unit and generating and storing corresponding electric charge, the harvesting circuit comprising: a rectifying unit comprising a plurality of rectifiers each configured and operable to receive AC electric signals and generate corresponding DC electric power; and a charge collection unit configured and operable to receive the plurality of DC electric powers from said rectifying unit and converting and accumulating them into the electric charge presenting harvested energy. The input signal adapting circuit has an input connected to the antenna unit and an output connected to the rectifying unit, the input signal adapting circuit being configured and operable for adjusting a predetermined electrical property of the antenna unit and rectifying unit to thereby optimize receipt of the electric output of the antenna unit to the harvesting circuit.

The invention relates to a method for supplying an electrical energy-converting implant with electrical energy, wherein an electrical voltage source is provided, wherein electrical voltage is generated by the linear movement of a piston of a free-piston generator.

This disclosure provides systems and methods for delivering a neural stimulation pulse. A neural implant device can include an energy harvesting circuit configured to receive an input signal and generate an electrical signal based on the received input signal. A diode rectifier in series with the energy harvesting circuit can rectify the electrical signal. The energy harvesting circuit and the diode rectifier can be encapsulated within a biocompatible electrically insulating material. A neural electrode can be exposed through the biocompatible electrically insulating material. The neural electrode can be configured to deliver a neural stimulation pulse. The neural implant device can have a volume that is less than about 1.0 cubic millimeter.

This disclosure provides systems and methods for delivering a neural stimulation pulse. A neural implant device can include an energy harvesting circuit configured to receive an input signal and generate an electrical signal based on the received input signal. A diode rectifier in series with the energy harvesting circuit can rectify the electrical signal. The energy harvesting circuit and the diode rectifier can be encapsulated within a biocompatible electrically insulating material. A neural electrode can be exposed through the biocompatible electrically insulating material. The neural electrode can be configured to deliver a neural stimulation pulse. The neural implant device can have a volume that is less than about 1.0 cubic millimeter.

An intra cardiac device is disclosed. The device comprises means for transforming kinetic energy from heart tissue movement into electrical energy in use, from which electrical energy information in respect of heart function is obtainable. Furthermore, a system is disclosed, comprising one such intra cardiac device and at least one receiver, wherein the intra cardiac device comprises means of communication, through which said at least one device communicates with the receiver(s) wirelessly. In this way energy from heart movement provides self contained intra cardiac devices for conveniently monitoring or stimulating a patient's heart.

The invention relates to methods and compositions for preparing silk-based piezoelectric materials and methods for increasing piezoelectricity in silk matrices.

The module comprises a pendular unit with an elastically deformable piezoelectric beam having a clamped end and an opposite, free end, coupled to an inertial mass. The beam produces an oscillating electrical signal collected by electrodes, which is rectified and regulated to output a voltage for charging a battery. The number and configuration of the electrodes (T1, T2, B1, B2, N) carried by the piezoelectric beam define a plurality of pairs of electrodes between which a corresponding plurality of said oscillating signals can be simultaneously collected. A switching matrix, as a function of an input command, selectively switches the plurality of pairs of electrodes between each other according to a plurality of different series (S), parallel (P) and/or series-parallel (SP) configurations, the selected configuration being that which maximizes the power sent to the battery as a function of the voltage level (VBAT) present at the terminals of the latter.

The implant comprises a tubular body housing an energy harvesting module adapted to convert external stresses applied to the implant into electrical energy, and a rechargeable battery adapted to be charged by the energy harvesting module. During the storage, an external source physically separated from the implant is coupled to the implant rechargeable battery to maintain a minimum battery charge level. An interface circuit of the implant couples surface electrodes to the battery, with switching between: i) a transport and storage configuration where the electrodes are connected to the external source to receive from the latter a battery charging energy and/or to exchange communication signals with the outside through the wire link of the coupling; and ii) a functional configuration in which the surface electrodes are decoupled from the external source after the implant has been implanted. At least one of the implant surface electrodes is an auxiliary electrode that is not a cardiac potential detection/pacing electrode. In the transport and storage configuration, the interface circuit couple the auxiliary electrode to the implant rechargeable battery, and in the functional configuration, the interface circuit decouples the auxiliary electrode from the implant rechargeable battery and put the auxiliary electrode to a floating potential.