A dispensing device is disclosed which provides for dispensing multiple doses from a cylindrical volume. An actuator button moves a tooth to engage a series of links which move a stopper to dispense the doses.

A medical injection device, including: a medication container having a mov-able piston; a push rod assembly displaceably disposed in the medical injection device, the push rod assembly having a plurality of spaced-apart position setting means disposed along the length thereof, the push rod assembly selectively displacing the movable piston to dispense medicament from the medication container; a spring to bias the push rod assembly to move toward the distal end of the medical injection device; a releasable restraining means configured to releasably restrain the push rod assembly in a locked state against the biasing of the spring, wherein, upon release of the releasable restraining means, the push rod assembly moves under force of the spring toward the distal end of the medical injection device; and an arming means configured to move the push rod assembly toward the proximal end of the medical injection device.

A dispensing device is provided to dispense a designated amount of a material on every dose delivery operation. The dispensing device includes a thumb pad, a cam drum coupled to the thumb pad, and a pawl nut comprising a one-way pawl. The thumb pad may be pulled out in a direction away from a distal end of the dispensing device for setting a dose of the material to be dispensed out and may be pushed in towards the distal end for delivering the dose. The cam drum includes a plurality of linear cam profiles and a plurality of helical cam profiles that may be disposed on a surface of the cam drum. The one-way pawl may engage with a ratchet disposed at a distal end of the cam drum and may prevent a rotation of the cam drum in an undesired direction.

A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 μg/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 μg, 100 μg, 150 μg and 200 μg settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.

A medication delivery device is disclosed including a rack-and-pinion plunger drive system. The drive system includes an output drive having a pawled end movably coupled with the ratchet teeth of the plunger, and a pinion drive coupled between the housing, the output drive and an actuator. Actuator is longitudinally movable between dose set and delivery positions. Movement of the actuator causes rotation of the pinion drive along the rack to translate the output drive member with the pawled end that is engaged with the plunger ratchet teeth to distally advance the plunger. The device may include one or more of an end of dose mechanism to limit travel of the actuator, a load brake system to stop travel of the plunger under high input forces, a dose detection system, and a dose selector to vary the amount of dose set.

The disclosure relates to an injection device for setting and injecting pre-set or user-selectable doses of a medicament, the injection device comprising an elongated housing defining a longitudinal direction and configured to accommodate a cartridge containing the medicament, and a detector arrangement operable to detect a relative movement between a first element and a second element. The first element is subject to a first movement relative to the second element along a first longitudinal direction for setting of a dose, the first element is subject to a second movement relative to the second element along a second longitudinal direction for dispensing of the dose, one of the first movement and the second movement is a helical movement, and the other one of the first movement and the second movement is a sliding movement in the longitudinal direction. The second element comprises at least one reference element fixed to the second element.

A drug delivery system is provided that has an adjustable dose mechanism allowing setting and locking the dose then administration of the set dose. A method for administering a medicament using the drug delivery system is also provided.

A method of providing and/or injecting octreotide acetate to a subject in need thereof includes storing the octreotide acetate in a cartridge of a multi-use multi-dose injector provided with a variable dose setter and actuator. The injector includes a needle configured for subcutaneous administration of the octreotide acetate, the octreotide acetate having a concentration of 2,500 μg/mL. The method further includes providing, on the injector, a plurality of indicia only at prescribed doses of 50 μg, 100 μg, 150 μg and 200 μg settable via the dose setter without indicia between said prescribed doses; and permitting setting of a dose of the octreotide acetate by rotation of the variable dose setter, wherein the injector is configured to provide at least one audible feedback during the rotation.

A plunger rod insertion gauge for a precision dose delivery device is disclosed. The insertion gauge includes: an insertion gauge body including a handle portion and a gauge portion; wherein the gauge portion includes one or more plunger rod abutting surfaces and one or more flange abutting surfaces oriented substantially perpendicular to a plunger rod insertion axis; and wherein a dimension measured between the one or more plunger rod abutting surfaces and the one or more flange abutting surfaces defines a maximum plunger rod insertion depth for the precision dose delivery device. Other aspects are described and claimed.

A device for administering a fluid product includes a first housing part with a receiver for the product, a second housing part detachably connectable to the first housing part, a piston rod held such that it can be displaced for the exertion of an emptying movement, an actuatable or releasable drive element for the piston rod, a coupling element including a coupling input element that couples the drive element to the piston rod in a coupling engagement, transmits a driving force of the drive element to the piston rod, and triggers the emptying movement, and a decoupling element displaceably connected to the second housing part and coupled to the first housing part such that it is displaced, by a movement of the housing parts in relation to each other when the housing parts are separated into a decoupling position wherein the piston rod is decoupled from the coupling input element.