The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose cartridge and permit a user to set the delivery dose. The injector may include a housing, a cartridge containing medicinal product, the cartridge being retained within the housing, means for selecting a dose of medicinal product to be expelled, and means for expelling the selected dose of medicinal product. The housing may be a unitary housing within which the means for selecting a dose and the means for expelling the selected dose are moveably retained. Alternatively, the injector may include a housing, a piston rod, an insert located in the housing and through which the piston may rotate, ratchet means, a dose dial sleeve, a drive sleeve, a button located on the drive sleeve and rotatable with respect to the drive sleeve, and clutch means which upon depression of the button prevents rotation between the dose dial sleeve and the drive sleeve.

A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.

An administration instrument includes an injection button which can be pressed at an angle that is not parallel to a needle with respect to a direction in which the needle is inserted into skin. As a result, it is possible to prevent a force of pressing the injection button from being transmitted in the direction in which the needle is inserted into the skin deeper than initial insertion of the needle, thereby achieving an administration under a stable state.

A medicament delivery device includes a housing; a hollow plunger rod; a dose drum concentrically arranged between the housing and plunger rod and movable when setting and delivering a dose; and a plunger rod driver. The driver includes a hollow ratchet arm drum movably arranged within the plunger rod and fixed to the dose drum, with the arm drum and rod releasably coupled; a dose activator having a longitudinal rod movably arranged within and releasably coupled to the arm drum; a dose setting knob fixed to the dose activator and releasably coupled to the arm drum; and a resilient element arranged between the arm drum and dose activator that biasses them in a direction decoupling the longitudinal rod from the arm drum and coupling the knob with the arm drum, such that during dose setting, turning the knob forces the arm drum and dose drum to rotate together.

The disclosure is directed to a drive mechanism for use in a drug delivery device having a cartridge, the mechanism comprising a base element, a toothed piston rod movable from a first retracted position corresponding to a full cartridge to a second extended position corresponding to an empty cartridge, wherein the piston rod is guided within and movable relative to the base portion, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod, wherein the toothed piston rod comprises multiple rigid rod pieces which are connected by hinges, and a drive spring, which is fixed to the base element with one end and fixed to the drive gear with another end and which exerts a force or torque to the drive gear for rotating the drive gear relative to the base element, which rotation results in a movement of the toothed piston rod. The drive spring is charged during manufacture or assembly, wherein the energy stored in the drive spring is sufficient to move the piston rod (from the first to the second position. The disclosure is also directed to a drug delivery device.

An injection device includes a housing, a plunger, a drive gear and a release trigger. The plunger includes a leadscrew and a cap attached thereto where, in use, the cap engages a bung of a cartridge containing medicament. The drive gear within the housing engages with the leadscrew such that rotation of the drive gear around the leadscrew drives the plunger axially through the housing towards the bung. The trigger includes a locking ring having generally axially extending teeth for engaging with corresponding teeth on the drive gear. The trigger is generally axially movable between an engaged position where the teeth are engaged and prevent rotation of the drive gear, and a disengaged position where the teeth are disengaged and enable rotation of the drive gear. Movement of the trigger between the disengaged and engaged position causes counter-rotation of the drive gear and retracts the plunger away from the bung.

A drug delivery device comprising; a housing; a cylindrical member configured to be rotatably supported inside the housing, wherein the outer surface of the cylindrical member is provided with a track comprising a sequence of encoded images; and a sensor directed at the track of the cylindrical member and configured to detect features of the encoded images.

The present invention relates to a torsion spring driven injection device for delivering set doses of a liquid drug. The injection device mechanism is encapsulated in a housing which also stores the cartridge containing the liquid drug. A needle cannula which is in liquid communication with the interior of the cartridge and which has a distal tip is shielded by a telescopically movable needle shield is used to inject the set dose. The needle cannula is preferably used for multiple injections and cleaned between subsequent injections. The drive mechanism further comprises a nut member engaging the piston rod and releasable coupled to the housing to operate as a pressure relief mechanism. The telescopically movable needle shield covering the distal tip of the needle cannula is formed to lock the nut member to the housing during injection.

The present disclosure concerns a mechanism for setting a dose of a medicament for a variable dose drug delivery device, comprising: a housing, a sleeve component configured to rotate relative to the housing during a dose setting operation, and a stop member which is configured to limit a total amount of possible rotation of the sleeve component to a maximum and, thereby, to limit a maximum settable dose, wherein the stop member is configured to allow varying the maximum which determines the total amount of possible rotation of the sleeve component.

A single hand operable injection control device (ICD) automatically injects material into a subject tissue at a rate controllably proportional to the rate of movement of the syringe. Squeezing the figure holds rotates a transmission/timing belt that is connected to a position reference member/guide that pushes against the subject tissue, causing the ICD body (containing the syringe) to push away from the subject tissue. The timing belt turns a worm gear that drives a syringe plunger into the syringe held by the ICD. The coordinated motions result in precise delivery of a unit volume/region of injectate into the subject. That is, a uniform “tube” of injectate is automatically laid in the cannula track.