An administration device for in particular intravitreal administration of a fluid, the administration device having a preferably pre-filled syringe and an actuation mechanism for actuating the syringe. The administration device preferably includes a priming device, in particular in addition to the actuation mechanism. It is preferably prevented that the priming device be advanced beyond a defined end position. The syringe can preferably be moved within a housing of the administration device and/or positioned completely inside the housing.

An injection device includes a housing, a dosing member held so as to be rotatable and fixed in the housing and an injection sleeve held so as to be rotationally fixed in relation to the housing and displaceable therein. A latching unit of the injection device is configured to act between two components thereof which, during setting of an amount of injection fluid to be dispensed, move relative to one another. A set amount of injection fluid is unequivocally assigned to each relative position of the two components.

A drug delivery device includes a housing, a cartridge received within the housing, with the cartridge configured to receive a medicament, a drive assembly received within the housing and configured to engage the cartridge and dispense medicament from the cartridge, and a needle actuator assembly received within the housing, with the needle actuator assembly including a patient needle configured to pierce a patient's skin. A bottom surface of the housing defines a port interface configured to receive an implanted injection port.

An ophthalmic device including a cannula having a cannula distal end, a lumen, and one or more orifices coupled to the lumen is provided. The cannula is configured to deliver a fluid. A sleeve is disposed around the cannula and has a sleeve distal end. A handle is coupled to the sleeve and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and configured to retract the sleeve relative to the cannula. The internal mechanism includes a follower fixedly coupled to the sleeve and moveable between distal and proximal positions, and a release member movable between an activated position and a release position. The release member is coupled to the actuator and configured to release a force that urges the follower from the distal position to the proximal position when the release member moves from the activated position to the release position.

A sensing system for determining a zero position of a medication delivery device. The sensing system includes at least one actuator member, a biasing member, a stop surface and a sensor. The stop surface is structured and arranged within the device housing for abutment by a push surface of the at least one actuator member as a screw element of the device screws to a zero position from a dosing position. The abutment forces the at least one actuator member to move relative to the screw element from a first position to a second position against a resistance provided by the biasing member. A sensor within an electronics module is adapted to recognize the at least one actuator member at the second position.

Data collection devices for attachment to injection devices are disclosed. In one embodiment, the data collection device includes: a body attachable to a dial member of the injection device, a sensor arrangement comprising a sensor and a scale, and a processor. The sensor is configured to detect a rotation of the body relative to a trigger of the injection device. The processor is configured to detect a rotation of the body relative to the trigger. One of the sensor and the scale is arranged in or on the body and wherein the other one of the sensor and the scale is located on the trigger or is rotationally lockable to the trigger configured to detect a rotation of the body relative to the trigger.

A medicament delivery device for injections or inhalations comprises a supplementary device affixed to it. The supplemental device is provided with an optical system for monitoring a dosage of medicament. The optical system is able to receive reflected and refracted optical images of the dosage value as the optical signals from the medicament delivery device and thus keep a dosage window on the medicament delivery device free for direct monitoring by a user due to changing the transferring of the optical signal direction. The supplemental device is able to analyze, record and display the dosage and the other relevant data on a display and inform the user. The supplemental device is also able to transmit the medicament delivery data to an external device. A method for collecting the medicament delivery data including the medicament dosage information from a dosage setting mechanism and controlling the dosage, recording and displaying the dosage data by the supplemental device on its display is disclosed. The method allows due to changing of the optical signal transmitting direction by the optical system also simultaneously monitoring the dosage window of the medicament delivery device. This method increases a safety and minimizes the dosage setting errors.

A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.

A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.