The present disclosure relates to an injection device configured to expel a dose of a medicament, the injection device comprising: an elongated housing extending in a longitudinal direction, a piston rod movable relative to the housing in a longitudinal distal direction to exert a dispensing pressure onto a bung of a cartridge at least partially filled with an injectable medicament, a rod extension movably arranged on or in a distal end of the piston rod, a driver operably engaged with the piston rod and movable relative to the housing in a longitudinal proximal direction for setting of the dose and movable relative to the housing in the longitudinal distal direction for dispensing of the dose, and an adjuster arranged on or in the driver and operably engaged with the rod extension to move the rod extension in longitudinal direction relative to the piston rod.

A needleless injector having a drive end with an energy source for propelling a quantity of fluid out a distal opening of a barrel of an ampule, wherein the drive end is provided with a cam and a follower for resetting the spring to enable multiple injections and deliveries of a discrete quantities of fluids out the barrel. The drive end can further include a carrier having a stepped barrel for sequentially moving a different surface of a different step adjacent the plunger of the ampule upon each reset of the spring.

A controlled multidosing delivery device for use with a syringe includes a housing, a plunger rod and a drive shell. The housing having an axially extending chamber including openings at either end, the distal end being adapted for attachment to the syringe barrel. The plunger rod includes a contact button at the proximal end of an elongated shaft and a pusher feature at the distal end. The drive shell is disposed for axial translation within the axially extending chamber. The drive shell includes a head disposed for translation along the axis to provide dose delivery, a plurality of engagement surfaces for engagement by the pushing feature, and a retention feature that inhibits proximal movement of the drive shell when engaged. Depression of the contact button axially translates the elongated shaft and pusher feature in engagement with the at least one of the engagement surfaces to translate the drive shell in the distal direction, whereby the retention feature engages to maintain axial position of the drive shell in the housing following dose delivery, and a biasing structure translates the plunger rod in the proximal direction following translation of the drive shell.

In a needleless syringe according to the present invention, a current is supplied to a solenoid coil to generate a magnetic field so as to move a moving magnetic body and a piston forward, and when the current to the solenoid coil is cut off, an elastic member for the moving magnetic body moves the moving magnetic body backward and an elastic member for the piston moves the piston backward, so that the piston to be injected by pressurizing a drug is configured to reciprocate repeatedly forward and backward and thus, a predetermined drug can be repeatedly injected at high speed. In addition, according to the present invention, time for which the current is applied to the solenoid coil, is adjusted to minimize recoil without adding a recoil offset structure so that the structure is simple and convenience of use can be improved.

A system for storing and delivering a predetermined amount of fluid includes a syringe including a barrel, a flange disposed at the proximal end of the barrel, and a plunger assembly configured to be received in the lumen of the barrel. The plunger assembly includes a piston and a plunger rod. The plunger rod is removably couplable to the piston at the distal end of the plunger rod and includes a thumb press flange at the proximal end of the plunger rod. The system further includes a stop feature that is removably couplable to the syringe or the plunger assembly. The stop feature is configured to arrest distal advancement of the plunger assembly relative to the syringe when the plunger assembly reaches a predetermined position relative to the syringe. The stop thus ensures that a predetermined amount of fluid remains in the barrel.

Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.

Disclosed in some forms is a process of limiting the impact of surgery on a nerve, the process comprising applying a therapeutic substance to the nerve during surgery. In some aspects, disclosed is a formulation for reducing nerve trauma comprising an active pharmacological ingredient adapted to intervene in the activation of pathways of cellular degradation within the nerve and a carrier adapted to reduce dissemination of the active pharmacological ingredient beyond the site at which its effect is intended.

A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a finger flange coupled to the syringe flange. Moreover, the system includes a stopper member disposed in the syringe interior. In addition, the system includes a plunger ratchet member coupled to the stopper member. The system also includes a plunger tube disposed coaxially around at least a portion of the plunger ratchet member and operatively coupled thereto.

A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a finger flange coupled to the syringe flange. Moreover, the system includes a stopper member disposed in the syringe interior. In addition, the system includes a plunger ratchet member coupled to the stopper member. The system also includes a plunger tube disposed coaxially around at least a portion of the plunger ratchet member and operatively coupled thereto.

The disclosure relates to a syringe, comprising a barrel and a plunger, wherein at least a part of said plunger is longitudinally slidably received in the barrel, wherein the plunger comprises a portion that is provided with at least one series of interspaced plunger formations, wherein the barrel is provided with a corresponding barrel formation for consecutively engaging successive ones of the plunger formations, wherein the syringe is arranged such as to be brought from a first state in which the barrel formation successively engages the plunger formations during slidable displacement of the plunger within the barrel, into a second state in which the barrel formation is held in a position spaced away from the plunger portion that comprises the plunger formations.