The present disclosure relates to a medicament delivery device. The medicament delivery device comprises a housing, a needle, a medicament delivery mechanism and an actuator. The actuator is moveable relative to the housing from an initial position to an intermediate position such that the actuator exerts a force on the first locking member to urge the first locking member from a locked state to an unlocked state wherein the first biasing member moves the needle from a retracted position to an extended position. The actuator is moveable relative to the housing from the intermediate position to a second position such that the actuator exerts a force on the second locking member to urge the second locking member from a locked state to an unlocked state wherein the second biasing member moves the dispensing member within the housing to dispense medicament from the reservoir when the reservoir contains medicament.

A medicament delivery device (100; 300; 400) comprises a chassis (124), a drive element (166) for driving a stopper (22) to expel the medicament through a cannula (144). A carrier (126) is arranged for movement with respect to the chassis (124). Insertion means (130, 202) biases the carrier (126) in an insertion direction. A control part (132) is biased for rotation with respect to the carrier (126). A locking element (176) prevents rotation of the control part (132) in an initial state. The locking element (176) is coupled to the drive element (166) such that the control part (132) is released for rotation when the drive element (166) reaches an activation position during a delivery stroke. Rotation of the control part (132) through a predetermined angle causes decoupling of the insertion means (130, 202) from the carrier (126) to allow movement of the carrier (126) in a retraction direction after the end of the delivery stroke.

A needle hub assembly for a pen needle includes a needle hub, a cannula or needle coupled to the needle hub, a retractable and compressible sleeve covering at least one end of the cannula, and an outer cover. The outer cover encloses the needle hub and the retractable sleeve. The retractable sleeve is coupled to the hub to cover the end of the cannula where the sleeve can pass through or can be pierced by the cannula and the sleeve retracts axially on the cannula. The sleeve is resilient and returns to an original configuration when an insertion force is released. The needle hub can have a first sleeve to cover a patient end of the cannula, and second sleeve to cover a non-patient end of the cannula where the sleeves retract onto the cannula or hub and expand to the original configuration to cover the ends of the cannula.

One embodiment is directed to a method for safe injection, comprising: providing an injection assembly and inserting a plunger tip of the injection assembly to a final insertion state and releasing an associated manual insertion load. A retraction load developed sufficient to cause the plunger tip to be proximally withdrawn pulls the retractable needle proximally relative to the needle housing to a retracted state wherein a distal tip of the needle becomes mechanically locked into an encapsulated configuration wherein it is no longer exposed for injection.

Barrel adapters for safety syringes include a barrel and a plunger assembly adapted to move within the barrel, a barrel tip adapted to be sealingly engaged with a distal end of the barrel and a needle retraction mechanism barrel having a needle subassembly and an actuator subassembly. The needle subassembly includes a needle, and a needle-over-mold (NOM) through which the needle extends. The needle subassembly is disposed at least partially within the barrel tip, and adapted to move from an injection position in which the needle extends from a distal end of the barrel tip to a retracted position in which the needle is disposed within at least one of the barrel tip or the barrel. The actuator subassembly includes a needle seal, a push-bar, and an actuator surface. The needle retraction mechanism barrel includes a biasing member and an actuable locking arrangement. A syringe includes such barrel adapters.

A machine vision based automatic needle cannula inspection system and methods of use. The system comprises of an inspection and control unit, image capture devices (32, 33), light sources (34, 35, 36, 37), a unit that makes the needle cannula (28) and the image capture device(s) (32, 33) rotate relative to each other, and a rejected part removal unit. By means of rotating the needle cannula (28) and image capture devices (32, 33) relatively, a plurality of images captured along the circumferential direction of the needle cannula are directly saved to a computer, the images are then screened, processed and analyzed to fulfill the automatic inspection of multiple quality and technical parameters of the needle cannula without the need to position the bevel area of cannula tip to a specific direction. Inspection parameters and accuracy can be set at any time, the system can automatically record classification and statistics of passed and rejected needle cannulae for query, and the rejected cannulae are removed automatically at next position. All the functions are completed at one work station, and needle cannula tips on both sides can be inspected simultaneously, if needed. Thereby the inspection efficiency and reliability are greatly improved, resulting in extremely extensive application prospects and huge economic values.

An apparatus includes a housing, a carrier, a medicament container, and a flexible member. The housing defines an opening placing a gas chamber of the housing in fluid communication with an exterior volume. The carrier has a proximal surface that defines a portion of the gas chamber. The medicament container is coupled to the carrier and has a distal end portion coupled to a delivery member. The medicament container containing a medicament and includes an elastomeric member that seals the medicament therein. The flexible member has a distal end portion coupled to the elastomeric member and a proximal end portion coupled to a valve member. The flexible member transitions from a collapsed configuration to an expanded configuration when the elastomeric member moves within the medicament container. The flexible member moves the valve member relative to the opening when the flexible member transitions from the collapsed configuration to the expanded configuration.

An auto-retractable blood collection needle, including: a needle holder including a first tube, a second tube and a holder tail; a needle in stalled in the first tube; a built-in sliding sleeve which is elongated and through and has a C-shaped cross section; a needle shield which is hollow and elongated; and a spring sheathed on the first tube. The second tube is installed in the built-in sliding sleeve and is capable of sliding back and forth. The built-in sliding sleeve is installed in the needle shield and is capable of sliding back and forth. A locking mechanism is formed by the holder tail and the needle shield. When the holder tail is unlocked from the needle shield, a force of the spring pushes the second tube to slide backward, and then the built-in sliding sleeve is driven to slide rearward to lock with the needle shield.

A device includes a housing having a first end, a second end, a first cylinder, a second cylinder parallel to the first cylinder, and a channel connecting the first and second cylinders near the second end. A piston is positioned within the first cylinder. A cartridge containing a therapeutic agent is positioned within the second cylinder. A needle hub containing a needle is positioned within the second cylinder between the cartridge and the first end. A septum is positioned at the first end. A fluid is positioned within the first cylinder. When the device is activated, the piston travels toward the second end, forcing some of the fluid to travel from the first cylinder into the second cylinder, forcing the cartridge toward the first end, causing the needle to penetrate the cartridge and the septum, and causing at least some of the therapeutic agent to extrude through the needle

A combination plunger, a mixing device and a mixing syringe including the same are provided. The mixing syringe includes concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. The combination plunger includes a mixing plunger and a delivery plunger and a biasing means. The mixing plunger is slidably located in the outer chamber and translated by coordinated depression of the delivery plunger to transfer a first substance from the outer chamber to mix with a second substance in the inner chamber. After the mixing stage is complete, the delivery plunger is disengaged from the mixing plunger and permitted, such as by rotation, to be further depressed in the axial direction to deliver fluid contents of the mixing syringe to a recipient. The mixing syringe needle is then retracted as result of engagement by the delivery plunger and activation of the biasing means.