An injection device (10) comprising a housing (12), a needle hub (38) slidable within the housing (12), a needle (40) having a distal end piercing tip (42) and a proximal end piercing tip (44), the needle hub being moveable from a first position wherein the distal end piercing tip (42) is within the housing to a second position wherein the distal end piercing tip (42) extends outwardly of the housing (12), a spring (23) biassing the needle hub (38) towards the first position, and a cartridge receiving member (48) mounted within the housing (12), and a plunger rod assembly (66) for exerting pressure on the cartridge receiving member (48) to move the cartridge (26) and the needle hub (38) from the first position to the second position, the plunger rod assembly (66) and the cartridge receiving member (48) being arranged such that when the cartridge rod assembly is pushed, a rotational movement is imparted to the cartridge receiving member (48) to thereby prevent access to the cartridge after injection.

A retractable syringe device includes: a handle including a hollow body for receiving a syringe through an opening of the handle, the hollow body including a syringe actuator that moves the syringe between a distal position and a proximal position; and an instrument distally extending from the handle, the instrument including a channel extending through the instrument, the channel configured to receive a needle coupled to the syringe. When the syringe is in the distal position, a distal end of the needle distally extends from the instrument, and when the syringe is in the proximal position, the distal end of the needle is retracted into the channel. The handle of the device can include a fixed or removable structure for removably coupling to a proximal end of a shaft of an endoscope.

The present invention relates to a syringe with an improved needle retraction mechanism, comprising: (a) a cylindrical barrel, (b) a needle holder, (c) a hollow plunger, (d) a rod, (e) an extractor element, and (f) a recovery tension or compression spring, the extractor element being movably displaceable from an advanced position to a retracted position, said extractor element having a male protrusion to engage the internal cavity of the needle holder to join the extractor element to the needle holder, and hooking means defining a connection between the plunger and the extractor element, and wherein the axial hole of the plunger is defined by a plurality of bendable flanges which are configured to slide over the needle holder, said bendable flanges thereby bending outwardly and expanding the axial hole of the plunger, and whereby the extractor element is disconnected from said plunger and is retracted towards its retracted position. The present invention also relates to a syringe kit wherein the syringe is provided with an improved needle retraction mechanism as described herein.

A needle hub assembly for a pen needle includes a needle hub, a cannula or needle coupled to the needle hub, a retractable and compressible sleeve covering at least one end of the cannula, and an outer cover. The outer cover encloses the needle hub and the retractable sleeve. The retractable sleeve is coupled to the hub to cover the end of the cannula where the sleeve can pass through or can be pierced by the cannula and the sleeve retracts axially on the cannula. The sleeve is resilient and returns to an original configuration when an insertion force is released. The needle hub can have a first sleeve to cover a patient end of the cannula, and second sleeve to cover a non-patient end of the cannula where the sleeves retract onto the cannula or hub and expand to the original configuration to cover the ends of the cannula.

An auto-injector operable to deliver a drug to a patient. The auto-injector may include a storage assembly with a first compartment and second compartment arranged to transition from an initial state in which the first compartment and the second compartment are separated to a merged state. The auto-injector may include a merging trigger configured for actuation responsive to manipulation and a merging mechanism comprising a compression element. Actuation of the merging trigger may cause movement of the merging mechanism such that the compression element compresses the first compartment.

Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a housing, a container, a trigger member, and an interlock assembly. The trigger member may be selectively moveable relative to the housing to activate operation of at least one activatable element of the drug delivery device. The interlock assembly may include a lever mounted rotatably relative to the housing, a proximity sensor moveable between a first position extending beyond an exterior surface of the housing and a second position retracted toward the housing, and a rotational biasing member operably connected to the proximity sensor via the lever. When the proximity sensor is in the first position, the interlock assembly may limit movement of the trigger member relative to the housing. The rotational biasing member may be configured to exert a torque biasing the proximity sensor toward the first sensor position.

A therapeutic agent delivery system includes a therapeutic agent delivery assembly carried by a housing. The therapeutic agent delivery assembly includes a chamber including a first passageway, a therapeutic agent carried in the first passageway, and a needle in communication with the first passageway. The therapeutic agent delivery assembly is translatable relative to the housing from a stowed configuration to a deployed configuration. The therapeutic agent delivery assembly is also translatable relative to the housing from the deployed configuration to a retracted configuration. The system further includes a user input that is actuatable to translate the therapeutic agent delivery assembly from the stowed configuration to the deployed configuration. The system further includes a retraction mechanism that is actuatable to translate the therapeutic agent delivery assembly from the deployed configuration to the retracted configuration.

A needle-based device includes a barrel as a body thereof and a needle. A portion of the needle is received within the barrel and glued thereinto to cause the needle to protrude from the barrel. The needle-based device also includes a needle shield to protect an entire length of the needle protruding from the barrel based on completely encompassing the entire protruding length of the needle in a first state of disuse of the needle-based device. The barrel includes wings on lateral sides of an outer wall thereof. The wings extend perpendicular to a length of the barrel to couple the needle shield to the barrel in the first state of disuse of the needle-based device.

A method includes protecting an entire length of a needle of a needle-based device protruding from a needle mount or a body of the needle-based device in a first state of disuse thereof based on providing a needle shield encompassing the entire protruding length of the needle, and encompassing the needle shield completely in the first state of disuse with an external cap. The method also includes providing a guide element protruding inward from an end of the external cap farthest away from the needle mount or the body of the needle-based device, internal to the external cap parallel to a length of the external cap and through the needle shield such that, in the state of disuse, the guide element at least partially envelops the needle therewithin to prevent significant lateral movement of the needle and prevents the end of the external cap from touching the needle.

An autoinjector and method of injection are described. A power spring causes rotation of a drive nut about the central axis of the autoinjector that, in turn, causes a middle screw to rotate in the same direction as the drive nut and also to move in the distal direction while pushing a center screw in the distal direction that pushes the syringe and needle. The center screw also pushes a plunger that pushes the fluid out of the syringe. After injection, a locked retract screw is freed and rotates in the same direction as the middle screw causing the syringe to retract the syringe into the housing.