Autoinjectors and methods of injection are described that feature release mechanisms and/or end-of-dose sound which can operate in conjunction with a powered plunger to efficiently inject a controlled dose from a syringe.

A syringe cap and needle assembly includes a needle retainer, a needle member secured within the needle retainer, and a cap. The needle member further includes an exterior needle end that extends outside of a forward end of the needle retainer. The cap is configured to slideably move with respect to the needle retainer between at least a first position and a second position. in the first position, the cap substantially surrounds the exterior needle end. In the first position and the second position, the cap substantially surrounds at least a portion of the needle retainer. in the second position, at least a portion of the exterior needle end is not surrounded by the cap.

A needle assembly includes a needle hole having an inside diameter that is greater than an outside diameter of a needle, and by a moving-side guide integrally provided to a needle tip cover being engaged with a fixed-side guide fixedly provided to the needle, a guide mechanism is provided to guide the needle tip cover from a proximal end side towards a distal end side of the needle while maintaining a state of noncontact with the needle, and to guide the needle tip cover to a position where the needle tip cover covers the needle tip while deviating the needle tip cover in a direction in which the needle hole goes away from a center axis of the needle at a position beyond the needle tip, and avoiding contact of the needle tip with the needle hole.

A protective device, for covering a needle tip of a needle of a medical instrument after puncturing of a puncture object by the needle, includes an inner cylinder, an outer cylinder, and a spring. The outer cylinder receives a cam structure of the inner cylinder and has a guide passage structure that includes one or more guide passages. The outer cylinder is provided with a lateral top part and a distal-end inclined edge part as resistance force generating parts for causing the inner cylinder to generate a resistance force at a puncture position or in the vicinity of the puncture position.

An injector includes a hollow needle; a main body unit including a needle holding portion that holds the needle; and a protection device configured to cover the needle before and after puncturing a puncture target with the needle. The protection device includes: an inner member attached to the needle holding portion and being freely rotatable around an outer periphery of the needle holding portion; and m outer member configured to (i) cover an order side of the needle and the inner member before puncturing, (ii) expose the needle by moving toward a proximal end side relative to the main body unit at a time of puncturing, and (iii) cover a distal end of the needle by moving toward a distal end side relative to the main body unit after puncturing.

A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A first guide path, a second guide path and a third guide path may be disposed on the housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The retractable sheath also may have a guide element. The first, second and third guide paths are configured to slidingly receive the guide element. The device also having a first locking member, a second locking member, a rotating cam disposed in the housing body, and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection.

A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The safety needle device may include an activation latch, a lockout latch, a tether and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection. The safety needle device may include a slider element disposed above an activation latch. A method of drug delivery is also disclosed.

An injector includes a hollow needle; a main body unit including a needle holding portion that holds the needle; and a protection device configured to cover the needle before and after puncturing a puncture target with the needle. The protection device includes: an inner member attached to the needle holding portion and being freely rotatable around an outer periphery of the needle holding portion; and an outer member configured to (i) cover an outer side of the needle and the inner member before puncturing, (ii) expose the needle by moving toward a proximal end side relative to the main body unit at a time of puncturing, and (iii) cover a distal end of the needle by moving toward a distal end side relative to the main body unit after puncturing.

Disclosed is a method for assembling a safety device and mounting the safety device on a syringe member before the syringe member is filled, said method comprising the steps of: providing a sleeve, a spring element and a mounting element; introducing the spring element into the sleeve along a mounting direction; introducing the mounting element into the sleeve along the mounting direction; obtaining the safety device; before the syringe body is filled, mounting the safety device on the syringe body by connecting the mounting element to the syringe body.

A cartridge syringe system includes a syringe (5). The syringe has a tip-ward direction and a ring-ward direction. The syringe (5) has a syringe body (9) and an actuator ring (7). A shaft (10) slidably mounts the actuator ring (7) to the syringe body (9), with a harpoon (11) at a tip-ward end of the shaft (10). The syringe body (9) has a spiral mount external to the syringe body (9) for removably mounting a sheath (20) to the syringe body (9), on a cooperating internal spiral sheath mount. The syringe body (9) and the sheath have similar openings. The sheath opening can be rotated to coincide with the syringe body opening, for inserting a needle assembly into the syringe body, or for removing the needle assembly. The sheath opening can be rotated to obstruct the syringe body opening, for retaining the needle assembly in the syringe body.