The invention relates to electrochemical wound dressings wherein potential damage to healthy cells and granulating tissue induced by hypochlorite and/or hypochlorous acid is reduced by enabling effective removal or build-up of substantial concentrations thereof through use of catalysts and/or scavenging/sacrificing agents. In another aspect, the present invention relates to the use of the latter materials in medical devices and articles.

The invention relates to electrochemical wound dressings wherein potential damage to healthy cells and granulating tissue induced by hypochlorite and/or hypochlorous acid is reduced by enabling effective removal or build-up of substantial concentrations thereof through use of catalysts and/or scavenging/sacrificing agents. In another aspect, the present invention relates to the use of the latter materials in medical devices and articles.

A self-contained battery-free iontophoresis apparatus and method are provided.

Embodiments provide apparatus and methods for producing markings in the skin. One embodiment provides an apparatus for marking the skin comprising a housing and reservoir for storing a skin colorant. An electrode is positioned within the housing so as to be electrically coupled to the colorant in the reservoir and is configured to be coupled to a current source and return electrode. A colorant applicator having at least one fluid pathway is coupled to a housing distal end. The applicator proximal end is positioned such that the fluid pathway is coupled with the reservoir. The applicator distal end applies colorant to the skin surface through the fluid pathway as the applicator is moved across the skin. The electrode delivers current from the current source to the skin to transport charged pigment elements of the colorant into the skin using an electromotive driving force to produce a marking in the skin.

Provided is a patch able to produce micro-current to be applied on human skin including a support for electrodes spaced from each other and apt to create voltages typical of galvanic piles, connection means between the electrodes, an adhesive layer applied on one side of the support and apt to adhere to the skin and a protection liner applied on the adhesive layer, the support being a membrane permeable to the moisture inside the electrodes, and the connection means being defined by a material that is avid of moisture, such as silica impregnating the membrane.

An oral care implement having electrodes thereon. In one aspect, the oral care implement may include a handle and a head, the head having an exposed outer surface. A first depression is formed in the exposed outer surface of the head. A first sacrificial electrode is disposed within the first depression and has an exposed surface that is recessed relative to the exposed outer surface of the head. A second electrode is located on the head. Each of the first and second electrodes is operably coupled to a power source to have opposite electrical charges.

An oral care implement having electrodes thereon. In one aspect, the oral care implement may include a handle and a head, the head having a transverse through hole defined by an upper surface and a lower surface. A first electrode and a second electrode are located on the head and operably coupled to a power source to have opposite electrical charges. At least one of the first and second electrodes may be located on one of the upper and lower surfaces of the transverse through hole. In some embodiments, the first electrode is located on the upper surface of the transverse through hole and the second electrode is located on the lower surface of the transverse through hole.

In one aspect, the disclosure relates to drug delivery devices for the ionophoretic delivery of a therapeutic agent(s) to the eye. In some aspects, the disclosed ionophoretic ocular delivery device is configured for delivery of a therapeutic agent to the anterior portion of the eye. In various aspects, the present disclosure provides methods for treatment of an ophthalmological disorder, disease, or clinical condition by delivering a therapeutic agent(s) to the eye using a disclosed ionophoretic ocular delivery device. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

When a device mounted on a mask pack, and a mask pack and a kit including the device are used, the mask pack may be well attached onto an application site, for example, skin; delivery of a bioactive material via the skin may improve; and itching, pain, burning, and erythema that may occur during a process of delivering the bioactive material to the skin may be prevented by using the device including an electrode.

A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.