A localised transdermal iontophoretic drug delivery system which controls localised transdermal drug delivery doses, transdermal drug delivery depths and transdermal drug delivery speeds is provided. The system includes a power supply, a current driving assembly, an optional switch matrix or multiplexer, and electrode assemblies or an electrode assembly array. The localised transdermal iontophoretic drug delivery system accurately controls a drug delivery current distribution between any electrode combination, so as to locally control a transdermal drug delivery dose, a transdermal drug delivery depth and a transdermal drug delivery speed, in order to implement accurate drug delivery to a user's skin.

A method and apparatus to treat hyperhidrosis is provided in which a battery provides a milliampere electrical current to the inside of a waterproof glove containing water and sealed to the user's arm so that circulation is not unduly restricted while the user can raise the water-filled gloves and hands above the user's head without leaking. A tapered portion on the proximal end of each glove is folded inside the glove to seal against the user's arm to form a pocket between the tapered portion which seals against the user's arms, and part of a wrist portion of the glove located radially outward of the tapered portion. When the user's gloves and hands rotate upward, water collects in the pocket(s) while the tapered portion provides a leakproof seal, thus allowing manual manipulation while wearing the water-filled gloves.

In one aspect, the disclosure relates to drug delivery devices for the ionophoretic delivery of a therapeutic agent(s) to the eye. In some aspects, the disclosed ionophoretic ocular delivery device is configured for delivery of a therapeutic agent to the anterior portion of the eye. In various aspects, the present disclosure provides methods for treatment of an ophthalmological disorder, disease, or clinical condition by delivering a therapeutic agent(s) to the eye using a disclosed ionophoretic ocular delivery device. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Improved hydrogel configurations for use with a TTField-generating system is disclosed. Also disclosed are kits containing the improved hydrogel configurations and methods of producing and using the improved hydrogel configurations.

Provided is an iontophoresis device. An iontophoresis device according to an embodiment of the present invention includes a power supply unit configured to supply power; two electrodes configured to supply current to a user's skin when brought into contact with the skin, thereby allowing an ionic drug or an active ingredient applied to the user's skin to permeate the skin by an electrical repulsive force; and a control unit configured to adjust an output value of a voltage or a current applied to the electrodes according to the user's skin condition, thereby allowing the user to feel a uniform intensity of electrical stimulation.

A medical device for administering a medicament is disclosed that includes a reservoir for storing the medicament, a current driver electrically coupled to an electrode, and an oscillation driver electrically coupled to a vibrational element. The electrode forms multiple channels in fluid communication with the reservoir. A method of administering a medicament is also provided.

A delivery system for local drug delivery to a target site of internal body tissue is provided. The delivery system comprises a source electrode adapted to be positioned proximate to a target site of internal body tissue. A counter electrode is in electrical communication with the source electrode, and is configured to cooperate with the source electrode to form a localized electric field proximate to the target site. A reservoir is configured to be disposed such that the reservoir is capable of interacting with the localized electric field. The reservoir is configured to carry a cargo capable of being delivered to the target site when exposed to the localized electric field. Associated methods are also provided.

Disclosed is a mask sheet and a sheet mask using the same, and more particularly an eco-friendly mask sheet having electrical conductivity and antibacterial function and a sheet mask using the same. The sheet mask includes a knit mask sheet having 1 to 20 wt. % of an electrically conductive fiber containing a copper component; and a cosmetic composition soaking into the mask sheet.

A system is provided for healing a wound. The system includes a flexible body, a therapeutic agent delivery mechanism, a suction mechanism, and a power source. The flexible body includes a cover film having oppositely disposed first and second surfaces that define a compartment. The compartment includes a first porous material, a second porous material, and at least one electrode disposed therein. The second porous material is disposed between the first porous material and the at least one electrode. The therapeutic agent delivery mechanism and the suction mechanism are fluidly connected to the compartment. The power source is in electrical communication with the at least one electrode.

A modular stimulus applicator system and method are disclosed. The system includes a plurality of wirelessly controlled stimulus pods, anchored to a patient's body, and configured to deliver stimulus to the patient's body. The stimulus can be heat, vibration, or electrical stimulus, or any combination thereof. The stimulus pods are controlled by a control station that can include a user-interface through which the patient can control application of the stimulus.