In certain variations, systems and/or methods for electromagnetic induction therapy are provided. One or more ergonomic or body contoured applicators may be included. The applicators include one or more conductive coils configured to generate an electromagnetic or magnetic field focused on a target nerve, muscle or other body tissues positioned in proximity to the coil. One or more sensors may be utilized to detect stimulation and to provide feedback about the efficacy of the applied electromagnetic induction therapy. A controller may be adjustable to vary a current through a coil to adjust the magnetic field focused upon the target nerve, muscle or other body tissues based on the feedback provide by a sensor or by a patient. In certain systems or methods, pulsed magnetic fields may be intermittently applied to a target nerve, muscle or tissue without causing habituation.

The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, minimally invasive systems, devices and methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.

A method for treating anxiety disorders may include applying a first pair of electrodes on the left side of a subject's head and a second pair of electrodes on the right side of the subject's head; applying a first stimulus carrier of a first magnitude to the first pair of electrodes and a second stimulus carrier of a second magnitude to the second pair of electrodes, wherein the first and second stimulus carriers combine to produce a stimulus having a frequency between 1 Hz and 1 kHz; and steering the stimulus toward the subject's left amygdala.

The lead implanted in a body to apply electrical stimulation to body organs may include: an electrode wire having one end provided as an insertion portion to be inserted into a body and the other end provided as an interface portion for connection with an external device to transmit a stimulation signal: a plurality of first electrodes in the insertion portion; a plurality of second electrodes on the interface portion; and a plurality of signal lines interconnecting the first electrodes and the second electrodes, wherein the insertion portion of the electrode wire includes a plurality of support portions on which the first electrodes are respectively disposed and a plurality of stretchable portions between the support portions and expandable and contractible, and further includes an operation unit for pushing or pulling each support portion in a longitudinal direction of the electrode wire to adjust a position of the support portion.

Methods for treating post-traumatic stress disorder (PTSD) and/or for reducing a risk associated with developing PTSD in patients via therapeutic renal neuromodulation and associated systems are disclosed herein. Sympathetic nerve activity can contribute to several cellular and physiological conditions associated with PTSD as well as an increased risk of developing PTSD following a traumatic event. One aspect of the present technology is directed to methods for improving a patient's calculated risk score corresponding to a PTSD status in the patient. Other aspects are directed to reducing a likelihood of developing PTSD in patients presenting one or more PTSD risk factors. Renal sympathetic nerve activity can be attenuated to improve a patient's PTSD status or risk of developing PTSD. The attenuation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly configured to use, e.g., electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the renal sympathetic nerve.

A system for brain stimulation of a patient is provided, the system having an implantable stimulator, at least one sensor component for acquiring at least one measure indicative of patient's mood, and at least one implantable stimulation electrode, designed for providing electrical pulses stimulating inside the patient's brain. The at least one stimulation electrode is connectable, through an implantable connector, to the implantable stimulator, the implantable stimulator having at least one programmable channel for conducting the electrical stimulation pulses to the at least one stimulation electrode, and being adapted for receiving continuous input signals from the at the least one sensor component. The system also has a computational unit for processing the at least one measure, and a patient's body external control interface (5) for patient and/or physician interactions.

Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.

A system for treating a patient comprises a stimulator for stimulating brain tissue, a controller for setting stimulation parameters and a diagnostic tool for measuring patient parameters and producing diagnostic data. The stimulation parameters comprise test stimulation parameters and treatment stimulation parameters. The stimulator delivers test stimulation energy to the brain tissue based on at least one test stimulation parameter and delivers treatment stimulation energy to the brain tissue based on at least one treatment stimulation parameter. One or more treatment stimulator parameters are determined based on the diagnostic data produced by the diagnostic tool The system is constructed and arranged to treat a neurological disease or a neurological disorder. Methods of treating a neurological disease or neurological disorder are also provided.

Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.

A method of stimulating a patient's brain comprising delivering an electrical stimulation to at least one electrode causing stimulation of a person's anterior cingulum bundle, or especially causing stimulation of a person's dorsal portion of an anterior cingulum bundle resulting in emotional change(s) in a patient comprising one or more of the following: anxiolysis, mirth, analgesia, improved affective tone, enhanced cognitive focus, increased well-being, engagement, or optimism. Further embodiments contemplate an apparatus. Further embodiments contemplate two implanted electrodes within the dorsal portion of the anterior cingulum bundle spaced between about 5 mm and 8 mm apart, having electrical stimulation parameters of between about 1.0 mA and about 3.5 mA, between about 100 Hz to about 150 Hz, and having a pulse width of between about 100 microseconds to about 200 microseconds.