Cochlear implant systems can comprise a cochlear implant system comprising a cochlear electrode, a stimulator in electrical communication with the cochlear electrode, a return electrode, and one or more controllers. The cochlear electrode can include a first contact electrode and the stimulator can include a first source element in electrical communication with the first contact electrode. The one or more controllers can be configured to cause the stimulator to emit a predetermined current from the first source element to the return electrode via a first current path and determine a first voltage at the first contact electrode and a second voltage at the return electrode. The one or more controllers can determine an impedance associated with the first current path and determine one or more stimulation parameters, such as a compliance voltage for sourcing a prescribed current, for the source element based on the determined impedance.

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit configured to generate one or more electric fields and a control circuit in communication with the electric field generating circuit. The control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit. The system can include two or more electrodes to deliver the electric fields to a site of a cancerous tumor within a patient and a temperature sensor to measure the temperature of tissue at the site of the cancerous tumor. The control circuit can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.

Disclosed herein is a non-invasive intraoral neurostimulation device and method for treating obstructive sleep apnea (OSA) while improving adherence, effectiveness, and outcomes. The intraoral neurostimulation device includes a mouthpiece, at least one electrode pair having a reference electrode and a stimulating electrode supported by the mouthpiece, and a substrate positioned between a tongue of a user and the stimulating electrode. The intraoral neurostimulation device is configured to deliver non-invasive electrical neurostimulation to the motor neurons of at least one genioglossus muscle to induce a muscle contraction of the tongue, thereby eliminating the blockage and returning normal airflow to the user. In certain embodiments, the intraoral neurostimulation device is paired with a respiratory sensor to deliver stimulation synchronized with the respiratory rhythm of the user or deliver stimulation only during apneic episodes, reducing the total amount of stimulation time.

Embodiments herein relate to a medical device for treating a cancerous tumor, including an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor and control circuitry in communication with the electric field generating circuit. The medical device includes one or more supply wires in electrical communication with the electric field generating circuit and one or more supply electrodes. The supply electrodes are configured to deliver an electric field at or near the site of the cancerous tumor. The medical device can include one or more sensing wires in electrical communication with the control circuitry and one or more sensing electrodes. The sensing electrodes can be configured to measure an impedance of the cancerous tumor at at least two different electric field strengths. Other embodiments are also included herein.

Methods and systems for obtaining and analyzing electromyography responses of electrodes of an implanted neurostimulation lead for use neurostimulation programming are provided herein. System setups for neural localization and/or programming include a clinician programmer coupleable with a temporary or permanent lead implantable in a patient and at least one pair of EMG sensing electrodes minimally invasively positioned on a skin surface or within the patient. The clinician programmer is configured to determine a plurality of recommended electrode configurations based on thresholds and EMG responses of the plurality of electrodes and rank the electrode configuration according to pre-determined criteria. The clinician programmer further includes graphical user interface on which the plurality of recommended electrode configurations are displayed for modification and/or selection by a clinician in programming an IPG or EPG coupled with the lead to apply a neurostimulation treatment according to the selected electrode configuration.

A system for stimulation of a nerve and measuring impedance. The system includes a neural interface device including a plurality of electrodes; a voltage or current source operatively connected to at least a subset of the electrodes, wherein the voltage or current source is configured to generate an electrical signal to be applied to the electrodes; an impedance measuring module operatively connected to at least a subset of the electrodes, wherein the impedance measurement module is configured to measure the impedance between the electrodes; and a controller arranged to determine an amplitude of an action potential induced in the nerve, via the electrical signal, based on the measured impedance and to adjust the electrical signal in order to induce an action potential having a target amplitude.

Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy. The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.

In one embodiment, an implantable pulse generator (IPG) for providing a neurostimulation therapy, comprises: pulse generation circuitry and pulse delivery circuitry for controlling generation and delivery of electrical pulses to a patient using one or more electrodes of a stimulation lead; measurement circuitry for determining characteristics of one or more electrodes selected for delivery of electrical pulses; and a processor for controlling the IPG according to executable code; wherein the IPG is adapted to calculate values for an impedance model of the one or more selected electrodes using the determined plurality of voltage measurements and to adjust current levels for the exponentially decreasing current pattern based on the calculated values for the impedance mode.

Embodiments are directed to an implantable medical device comprising stimulation circuitry for controlling delivery of a medical therapy to a patient, a processor for controlling the IMD according to executable code, and a power source. The implantable medical device may further include current regulator circuitry comprising electrode selection circuitry that is configured to select electrodes for use during a discharge mode, and a programmable current regulator configured to provide an exponentially decreasing discharge current to the selected electrodes from the power source. A current output of a programmable current regulator may be decreased in precalculated steps to create the exponentially decreasing discharge current applied to the selected electrodes.

This disclosure relates to medical implant systems and apparatuses capable of treating a seizure condition through the use of recording and stimulating electrodes. The apparatus includes an internal pulse generator in communication with a wireless communication module; one or more recording electrodes in communication with the internal pulse generator, wherein the one or more recording electrodes are configured to monitor to detect one or more field potentials produced by neural tissue in proximity to the one or more recording electrodes; one or more stimulating electrodes in communication with the internal pulse generator, wherein the one or more stimulating electrodes are configured to stimulate the vagus nerve.