Systems and methods are provided for optimizing hemodynamics within a patient's heart, e.g., to improve the patient's exercise capacity. In one embodiment, a system is configured to be implanted in a patient's body to monitor and/or treat the patient that includes at least one sensor configured to provide sensor data that corresponds to a blood pressure within or near the patient's heart; at least one adjustable component designed to cause blood to flow in a direction opposite to the normal direction (regurgitation) within the patient's heart; and a controller configured for adjusting the function of the at least one adjustable component based at least in part on sensor data from the at least one sensor.

An implantable wireless sensor is provided that comprises a plurality of substrates joined together to form a body with a hermetically sealed cavity therein. A capacitor (C) is provided within the cavity. A first capacitor plate is formed on an internal surface of the first substrate. An inductor (L) is provided within the cavity and coupled to form an LC resonant circuit. At least a portion of the first substrate comprises a deflectable region mechanically coupled to the first capacitor plate. The deflectable region is configured to deflect in response to changes in pressure in the artery altering a spacing between the capacitor plates and altering a resonant frequency of the LC resonant circuit. First and second anchoring elements are coupled to the body and include flexible wire loops configured to extend outward from the body to lodge within a lumen of the artery.

A method and system are provided for determining a pressure associated with a lumen of a patient. A wireless sensor is positioned in the lumen of the patient. The sensor has a body with a pressure sensitive surface, including a sealed cavity that holds an inductive-capacitive (LC) resonant circuit. A capacitance of the LC resonant circuit is configured to vary in response to changes in pressure in the lumen. The LC resonant circuit has a charge time related to a quality factor (Q) of the LC resonant circuit. The LC resonant circuit is energized with an energizing signal during a measurement cycle. The energizing signal has a duty cycle with an on-time that is set, in part, based on the charge time. A ring down response is received from the wireless sensor. The ring down response is utilized to calculate the pressure associated with the lumen of the patient.

An apparatus for controlling the flow of urine in a urethra of a patient, comprising an implantable adjustable constriction device for constricting the urethra, a control device for controlling the constriction device, an operation device for operating the constriction device to change the constriction of the urethra, and an energy source for supplying energy for the operation device. The control device comprises a temperature sensor configured to sense a temperature of the apparatus or a temperature of the patient.

A delivery device for installing a medical device in a patient comprising a body portion having a proximal end and a distal end, the distal end having a chisel shaped tip, a receptacle disposed in the distal end of the body portion for receiving a medical device for implanting in the patient, a handle disposed at the proximal end of the body portion for facilitating advancement of the proximal end of the body portion into the patient.

An apparatus for controlling the flow of urine in a urethra of a patient is disclosed. The apparatus comprises an implantable adjustable constriction device for constricting the urethra to influence the flow in the urinary tract, an operation device for operating the constriction device, and a control device for controlling the operation device to constrict the urethra and to release the urethra. Further, the apparatus comprises an energy source for supplying energy to the operation device, wherein the control device is configured to determine the current state of the energy source, and wherein the control unit is connected to an internal signal transmitter configured to transmit information related to the current state of the energy source.

Systems and methods for pacing cardiac conductive tissue are described. A medical system includes an electrostimulation circuit that may generate His-bundle pacing (HBP) pulses for delivery at or near the His bundle. In response to the delivery of the HBP pulse, the system senses a near-field cardiac activity representative of excitation of a para-Hisian myocardial tissue, and a far-field cardiac activity representative of excitation of the His bundle and a ventricle. The system classifies a tissue response to HBP into one of a plurality of capture types based on the sensed near-field and far-field cardiac activities. The system includes a control circuit to adjust one or more stimulation parameters based on the classified capture type. The electrostimulation circuit generates and delivers the HBP pulses according to the adjusted stimulation parameters to excite the His bundle.

This document discusses, among other things, a modular antitachyarrhythmia therapy system. In an example, a modular antitachyarrhythmia system includes at least two separate modules that coordinate delivery an antitachyarrhythmia therapy, such as defibrillation therapy. In another example, a modular antitachyarrhythmia therapy system includes a sensing module, an analysis module, and a therapy module.

A method and apparatus for treatment of hypertension and heart failure by increasing secretion of endogenous atrial hormones by pacing of the heart. Pacing is done during the ventricular refractory period resulting in premature atrial contraction that does not result in ventricular contraction. Pacing results in the atrial wall stress, peripheral vasodilation, ANP secretion. Concomitant reduction of the heart rate is monitored and controlled as needed with backup pacing.

An apparatus for controlling a flow of urine in a urethra of a patient is disclosed. The apparatus comprises an implantable constriction device for constricting the urethra to influence the flow in the urinary tract, comprising a plurality of clamping elements configured to be arranged in a common plane intersecting the urethra and to be radially movable towards and away from a central axis of the urethra. The apparatus further comprises an operation device configured to operate the clamping elements, and an implantable motor configured to operate the operation device. The operation device is configured to operate the movement of the clamping elements such that the movement is predominantly inelastic, and such that a clamping force, acting on the urethra, is distributed between the clamping elements.