A method for waking up an implantable medical device from a dormant state, an implantable medical device, and a system that includes such an implantable medical device and an external device. The implantable medical device is woken up from a dormant state by sending a modulated wakeup signal via a wireless link from an external device. The modulated wakeup signal is demodulated by way of a demodulator circuitry of the implantable medical device so as to produce a demodulated wakeup signal. The demodulator circuitry is permanently ready for operation. An awake state of the implantable medical device is then activated in response to the demodulated wakeup signal.

A system includes an interface assembly and electronic circuitry. The interface assembly is configured to receive DC power and a self-clocking differential signal comprising a data signal encoded with a clock signal at a clock frequency. The electronic circuitry is configured to recover, from the self-clocking differential signal, the data signal and the clock signal at the clock frequency, and to generate, based on the recovered clock signal at the clock frequency, a first synthesized clock signal at a first carrier frequency and a second synthesized clock signal at a second carrier frequency. The electronic circuitry is also configured to wirelessly transmit AC power and a data-modulated AC signal to an implantable stimulator implanted within a patient. The AC power is at the first carrier frequency and based on the DC power, while the data-modulated AC signal is at the second carrier frequency and based on the recovered data signal.

Presented herein are techniques for generating a stable reference clock for use by a short-range radio transceiver of an implantable component without the need for an X-tal oscillator within the implantable component itself. In accordance with certain techniques presented herein, the implantable component is in communication with a first external component via a closely-coupled link and in communication with a second external component via short-range radio link. The implantable component is configured to receive, from the first external component, signals via the closely-coupled link. The implantable component is configured to extract frequency information from these received signals and synchronize a carrier frequency of the short-range radio link to the frequency information extracted from the signals.

A prosthetic aortic valve is provided, which is configured to be delivered to a native aortic valve of a patient in a constrained delivery configuration within a delivery sheath. The prosthetic aortic valve includes a frame, which includes interconnected stent struts arranged so as to define interconnected stent cells; a plurality of prosthetic leaflets coupled to the frame; a cathode and an anode, which are mechanically coupled to the frame; and a prosthetic-valve coil, which is in non-wireless electrical communication with the cathode and the anode, and is coupled to a plurality of the stent struts, running along the stent struts so as to surround a plurality of the stent cells when the prosthetic aortic valve is in an expanded fully-deployed configuration upon release from the delivery sheath. Other embodiments are also described.

A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity.

Semi-autonomous vehicle apparatus which is controlled by a plurality of control sources includes a vehicle which may function autonomously and apparatus for control of the vehicle by either an onboard driver or a driver not situated onboard. The vehicle may also be controlled by an off-vehicle computational device. Hierarchy setting apparatus determines which one or combination of the possible control entities take priority. Persons using the apparatus are identified by either a password or, preferably by providing identification based on a biologic feature. Management of impaired vehicle operators is provided for.

A charger including a class E power driver, a frequency-shift keying (“FSK”) module, and a processor. The processor can receive data relating to the operation of the class E power driver and can control the class E power driver based on the received data relating to the operation of the class E power driver. The processor can additionally control the FSK module to modulate the natural frequency of the class E power transformer to thereby allow the simultaneous recharging of an implantable device and the transmission of data to the implantable device. The processor can additionally compensate for propagation delays by adjusting switching times.

The present application describes an apparatus for Neuromuscular Stimulation constituted by an implantable medical device for in-situ neuromuscular electrical stimulation (INES) and a controlling external device. The medical device can be placed in the neighbourhood, implanted beneath or on the thickness of the knee tendons or ligaments.

Exemplary embodiments of this disclosure include apparatus, systems and methods utilizing a passive, power-efficient backscattering communication system that enables transmitting data wirelessly between implantable magnetoelectric (ME) devices and an external base station. Certain embodiments encode the transmitted data through modulating the resonance frequency of a ME film by digitally tuning its electric loading conditions.

The disclosed techniques allow for externalizing errors from an implantable medical device using the device's charging coil, for receipt at an external charger or other external device. Transmission of errors in this manner is particularly useful when telemetry of error codes through a traditional telemetry coil in the implant is not possible, for example, because the error experienced is so fundamental as to preclude use of such traditional means. By externalizing the error via the charging coil, and though the use of robust error modulation circuitry in the implant designed to be generally insensitive to fundamental errors, the external charger can be consulted to understand the failure mode involved, and to take appropriate action.