Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy, The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.

Disclosed are various examples and embodiments of systems, devices, components and methods configured to rehabilitate or strengthen one or more muscles in a patient, and to reduce pain sensed by the patient, through a unique combination of electrical stimulation signals delivered to one or more target peripheral nerves. Medical electrical lead(s) comprising electrode(s) are positioned adjacent to, in contact with, or in operative positional relationship to, one or more target peripheral nerves of the patient. The target peripheral nerves typically comprise motor and sensory nerves. In one embodiment, first stimulation signals having a first range of frequencies are delivered through the electrode(s) to the target nerves to rehabilitate muscles enervated by the motor nerves. Second stimulation signals having a second range of frequencies are delivered through the electrode(s) to the target nerves to provide pain relief to the patient. The first range of frequencies is lower than the second range of frequencies.

The invention relates to a system for preventing and/or reducing muscle spasms and improving postural stability in a patient suffering from muscle spasm and postural instability. The system comprises an electrode configured to be positioned to stimulate a target dorsal root ganglion associated with the muscle spasm and postural instability. The system also comprises a pulse generator provided with an output port connectable to the electrode. The pulse generator includes a processor configured to generate an electric stimulation signal at the electrode while connected. Here, the electric stimulation signal stimulates the dorsal root ganglion with an electric pulse while so positioned. Further, the system comprises a user interface configured to set at least one user-specified parameter of the electric pulse.

A blood pressure controlling apparatus includes an acquiring part configured to acquire biological information indicating blood pressure of a subject, a producing part configured to produce a frequency modulated pulse train on the basis of the biological information, and a supplying part configured to supply an electrical current on the basis of the frequency modulated pulse train, to an electrode attached on the subject. The electrical current stimulates baroreceptor afferent nerves of the subject.

A system and methods utilizing electrical stimulation to achieve a desired therapeutic effect are provided. In one aspect, a method for controlling nerve activity in a subject is provided. The method includes receiving input indicating a desired therapeutic effect for at least one neural structure of a subject, and selecting, based on the input received, an electrical stimulation configured to achieve the desired therapeutic effect. The method also includes controlling a sympathetic nerve activity in the subject by delivering the electrical stimulation using electrodes positioned proximate to nerves innervating the subject's skin.

An implantable neurostimulator has an implantable electrode array comprising a plurality of stimulus electrodes. Each stimulus electrode is configured to deliver electrical stimuli to neural tissue. An implantable control module is configured to produce the electrical stimuli delivered by the stimulus electrodes, and is configured to effect current steering. The control module has a plurality of related current sources, each current source configured to deliver a respective stimulus current which is defined in a first part by a shared current control signal which is shared by each of the related current sources, and which is defined in a second part by a respective unique current control signal which is not shared by all of the related current sources.

This disclosure relates to implantable neuro stimulation devices with a feedback loop to control an amount of energy delivered into a neural tissue based on a measured evoked neural response. Stimulation electrodes deliver stimulation energy to neural tissue and a stimulator comprises a microprocessor and program memory with program code, which causes the microprocessor to perform closed-loop control of the stimulation energy based on a feedback signal that is indicative of an evoked neural response. A charge monitor monitors the delivery of energy to the stimulation electrodes by determining an amount of charge delivered by the stimulation electrodes and connected to the stimulator to provide a status signal indicative of the charge delivered to the stimulator. The device adjusts the control of the stimulation energy in response to the status signal from the charge monitor indicating undesirable charge delivery to the stimulation electrodes.

This disclosure is directed to devices, systems, and techniques for controlling electrical stimulation. In some examples, a system includes a user interface and processing circuitry. The processing circuitry is configured to output, for display by the user interface, a message requesting the patient perform a set of actions, receive, from the user interface, user input indicative of a patient response associated with the set of actions, and determine, based on the user input, one or more adjustments to a control policy which controls electrical stimulation delivered by a medical device based on a plurality of evoked compound action potentials (ECAPs) sensed by the medical device.

A nerve activity blocking system (100) includes a blocking electrode (102) configured to generate a blocking electrical signal that blocks, at least in part, an action potential propagating through a nerve system of a body. using a low frequency alternating current. The blocking electrical signal prevents propagation of the action potential by overriding another electrical signal controlling an organ of the body.

A neurostimulation device has at least three stimulation electrodes configured to deliver an electrical stimulus to neural tissue. A control unit is configured to deliver a first stimulus phase in which a first stimulus electrode delivers a supra-threshold stimulus component, returned by at least two other of the stimulation electrodes. The control unit is further configured to deliver at least a second stimulus phase in which at least two of the stimulus electrodes deliver a sub-threshold stimulus component, returned by the first stimulus electrode.