Implantable electrodes with power delivery wearable for treating sleep apnea, and associated systems and methods are disclosed herein. A representative system includes non-implantable signal generator worn by the patient and having an antenna that directs a mid-field RF power signal to an implanted electrode. The implanted electrode in turn directs a lower frequency signal to a neural target, for example, the patient's hypoglossal nerve. Representative signal generators can have the form of a mouthpiece, a collar or other wearable, and/or a skin-mounted patch.

A visual implant (2) comprises an array of micro-electrodes (4) including at least two stimulation micro-electrodes each comprising: a core (106) of conducting material; insulating material (108) surrounding the core; and a layer (112) of metal or metal oxide nano-structures deposited on tips of the micro-electrodes at a front end for interfacing with a target site for visual stimulation; and an integrated circuit (6) to control a pattern of stimulation current driven through the array of micro-electrodes.

A hearing device for use with a cochlear implant system is disclosed. An input portion receives, as a stimulus, an acoustic signal, converts the acoustic signal into an electrical acoustic signal and provides the electrical acoustic signal. A processing portion processes the electrical acoustic signal and conducts an active grounding procedure. An implant portion being implantable at least partially in a cochlea of the user comprises a plurality of operation electrodes and a reference electrode, e.g. an external electrode being grounded and implantable outside of the cochlea of the user. The operation electrodes are driven by the processing portion on the basis of the electric acoustic signal. An electrode state setting section sets the plurality of operation electrodes into one of a high impedance state, a grounded state and a stimulating state in which a signal based on the electric acoustic signal is supplied to a stimulation electrode of the plurality of operation electrodes. An electrode state setting pattern determining section selects, according to an operation mode of the cochlear implant system, one of a plurality of electrode state setting patterns, wherein each of the electrode state setting patterns is adapted to enable a stimulation by a stimulation electrode of the plurality of operation electrodes being in a stimulating state and at least one of the plurality of operation electrodes being in a grounded state or in a high impedance state. The electrode state setting section sets the plurality of operation electrodes into the specified electrode state according to the selected electrode state setting pattern.

An optimization algorithm is disclosed for optimizing an implantable pulse generator. The algorithm is particularly useful when one or more of the electrodes (e.g., the case electrode) is used to provide a common mode voltage (Vcm) to the tissue, which assists in sensing neural responses to the stimulation. The algorithm preferably optimizes both the compliance voltage VH used to power the simulation circuitry, and the strength of tissue driver circuitry used to provide Vcm to the tissue. The algorithm preferably considers information determined by VH measurement circuitry (which informs as to the ability to form prescribed stimulation pulses without loading), sensing monitoring circuitry (which informs as to the magnitude of the inputs of the sensing circuitry), and/or tissue monitoring circuitry (which informs as to adequacy of the strength of the tissue driver circuitry).

A motor device for stimulating muscle, including at least one electrode for generating electric current operatively attached to an electrode array and exposed on an inner surface of an array body, and a programming mechanism of a computer that executes an algorithm stored on non-transitory computer readable medium and includes an information storage mechanism and a user-operated interface in electrical connection with said at least one electrode for programming operation of said at least one electrode, said motor device being implanted in an individual and applying electric current to nerves at an area above an area of neurological damage.

High frequency stimulation for treating sensory and/or motor deficits in patients with spinal cord injuries and/or peripheral polyneuropathy, and associated systems and methods. A representative method includes addressing the patient's somatosensory dysfunction and/or motor dysfunction, resulting from neuropathy and/or spinal cord injury, by directing an electrical therapy signal to the patient's spinal cord region, the therapy signal having a frequency in a frequency range from 1.5 kHz to 100 kHz.

The present invention provides an implantable neuromodulation system for delivering an electrical signal to a nerve to stimulate, inhibit or block conduction of action potentials in the nerve. The system comprises a neural interface device comprising first and second electrodes; a signal generator and a first closed-loop controller configured to generate a control signal based a property of the signal based on a measured voltage across the first and second electrodes, and cause the signal generator to adjust the electrical signal to modify the property of the signal.

A medical apparatus for a patient comprises an external system and an implantable system. The external system is configured to transmit one or more transmission signals, each transmission signal comprising at least power or data. The implantable system is configured to receive the one or more transmission signals from the external system, and to deliver stimulation energy to the patient. Methods of delivering stimulation energy are also provided.

Representative methods, apparatus and systems are disclosed for providing concurrent electrical stimulation and electrical recording in a human or non-human subject, such as for neuromodulation, with the apparatus coupleable to an electrode array. A representative apparatus is typically an integrated circuit including: stimulation circuits, recording circuits, and blocking circuits responsive to control signals to block the stimulation voltage or current on an electrode from a corresponding recording circuit, while other recording circuits may simultaneously record electrical signals from other electrodes and generate recorded data. A representative stimulation circuit may include current sources; a first multiplexer for current source selection; a second multiplexer for electrode selection; a switchable voltage offset circuit; a switchable grounding circuit; and a stimulation controller providing control signals to provide the electrical stimulation, such as biphasic or monophasic stimulation, and bipolor or unipolar stimulation. Off-chip communication, control, along with power and voltage level control, are also provided.

Implantable electrodes with power delivery wearable for treating sleep apnea, and associated systems and methods are disclosed herein. A representative system includes non-implantable signal generator worn by the patient and having an antenna that directs a mid-field RF power signal to an implanted electrode. The implanted electrode in turn directs a lower frequency signal to a neural target, for example, the patient's hypoglossal nerve. Representative signal generators can have the form of a mouthpiece, a collar or other wearable, and/or a skin-mounted patch.