High frequency stimulation for treating sensory and/or motor deficits in patients with spinal cord injuries and/or peripheral polyneuropathy, and associated systems and methods. A representative method includes addressing the patient's somatosensory dysfunction and/or motor dysfunction, resulting from neuropathy and/or spinal cord injury, by directing an electrical therapy signal to the patient's spinal cord region, the therapy signal having a frequency in a frequency range from 1.5 kHz to 100 kHz.

Implantable electrodes with power delivery wearable for treating sleep apnea, and associated systems and methods are disclosed herein. A representative system includes non-implantable signal generator worn by the patient and having an antenna that directs a mid-field RF power signal to an implanted electrode. The implanted electrode in turn directs a lowerfrequency signal to a neural target, for example, the patient's hypoglossal nerve. Representative signal generators can have the form of a mouthpiece, a collar or other wearable, and/or a skin-mounted patch.

Selective high-frequency spinal cord modulation for inhibiting pain with reduced side effects and associated systems and methods are disclosed. In particular embodiments, high-frequency modulation in the range of from about 1.5 KHz to about 50 KHz may be applied to the patient's spinal cord region from an epidural, cervical location to address at least one of high back pain, mid-back pain, low back pain, and leg pain without creating paresthesia in the patient.

A system includes a vagus nerve stimulation (VNS) device configured to deliver a vagus nerve stimulation signal having an ON-period status and an OFF-period status, and a processor and a non-transitory computer readable memory. The memory stores instructions that, when executed by the processor, cause the system to synchronously record a first ECG profile of during the ON-period status and a second ECG profile during the OFF-period status, determine heart rate dynamics from the first and second ECG profiles, the heart rate dynamics including a plurality of R-R intervals in each ECG profile, generate display data configured to be displayed on a display, and transmit the display data to the display. The display data includes the R-R intervals for each of the first and second ECG profiles. The display data further includes a Poincaré plot.

A field measurement algorithm and measuring circuitry in an implantable stimulator, and an field modelling algorithm operable in an external device, are used to determine an electric field in a patient's tissue. The field measuring algorithm provides at least one test current between two electrodes, and a plurality of voltage differentials are measured at different combinations of the electrodes. The voltage differential data is telemetered to the field modelling algorithm which determines directional resistance at different locations in the patient's tissue. The field modelling algorithm can then use a stimulation program selected for the patient and the determined directional resistances to determine voltages in the patient's tissue at various locations, which in turn can be used to model a more-accurate electric field in the tissue, and preferably to render an electric field image for display in a graphical user interface of the external device.

A method of stimulating muscle in a person having neurological damage, by applying electric current to nerves at an area above an area of neurological damage, bypassing or bridging an area of neurological damage, and moving the muscle in a natural manner. A method of moving muscles of a paraplegic or a person who suffers from other movement-related disorders of the body by applying electric current to nerves at an area above an area of neurological damage, bypassing or bridging an area of neurological damage, and moving normally non-functioning muscles and moving normally non-functioning limbs.

Disclosed herein are systems and methods for nerve conduction block that can involve the delivery of relatively high amounts of charge safely to tissue. Such systems and methods can include control systems for safely monitoring a direct current electrode system, including delivering direct current via an electrode lead to a target tissue of a patient; measuring the driving voltage across the electrode; comparing the driving voltage across the electrode to predetermined threshold range values; measuring the body impedance; determining a voltage drop across the lead from the body impedance measurement; and adjusting the driving voltage to maintain the voltage drop across the lead within a predetermined voltage range.

A device for stimulating a nerve comprising: a first stimulation generating unit configured to generate and output a first intermittent current waveform comprising a sequence of first pulses to a first pair of electrodes; a second stimulation generating unit configured to generate and output a second intermittent current waveform comprising a sequence of second pulses to a second pair of electrodes; wherein the first and second intermittent current waveform have a difference in frequency so as to stimulate the nerve using interferential stimulation based on interference between the first and second intermittent current waveform; and a control unit configured to control the interferential stimulation and synchronize the first and the second stimulation generating unit.

An illustrative method may include 1) generating, by an implantable stimulator, stimulation sessions, wherein the implantable stimulator comprises a central electrode of a first polarity centrally located on a first surface of a housing of the implantable stimulator and an annular electrode of a second polarity and that is spaced apart from the central electrode; and 2) applying, by the implantable stimulator, the stimulation sessions by way of the central electrode and the annular electrode to a location within a patient.

A system may be used with a first neuromodulator of a first neuromodulator type and a second neuromodulator of a second neuromodulator type where the first neuromodulator is programmed with a first set of modulation parameter settings. The system may comprise an input configured for receiving the first set of modulation parameter settings for the first neuromodulator type, a processor configured to execute a programmed set of instructions to determine a second set of modulation parameter settings for the second neuromodulator type based on the first set of modulation parameter settings for the first neuromodulator type, and an output configured present the second set of modulation parameter settings for entering into a neuromodulator programmer. The neuromodulator programmer may be configured to program the second neuromodulator with the second set of modulation parameters.