The present disclosure provides systems and methods for combining tonic deep brain stimulation (DBS) and random DBS. A system includes a stimulation lead including a plurality of contacts, and an implantable pulse generator (IPG) communicatively coupled to the stimulation lead and configured to cause tonic stimulation to be delivered using one contact of the plurality of contacts, and cause random stimulation to be delivered using a subset of the remaining contacts of the plurality of contacts.

Devices, systems, and techniques are disclosed for determining spatial relationships between electrodes implanted within a patient. In one example, a medical device delivers, via a first electrode, an electrical stimulus and senses, for each other electrode, a respective electrical signal indicative of the electrical stimulus. The medical device determines, for each other electrode, a respective value for each respective electrical signal. The medical device determines, based on the respective values for each respective electrical signal and values of tissue conductivity of tissues of the patient interposed between the first electrode and the other electrodes, spatial relationships between the first electrode and each other electrode of the plurality of electrodes.

Presented herein are techniques for determining an arrangement of complex stimulation channels to optimally distribute sensory information across the channels of a multi-channel tissue-stimulating prosthesis. A tissue-stimulating prosthesis may initially be associated with a set of complex stimulation channels. A stimulation efficiency is determined for each complex stimulation channel within the set of complex stimulation channels. A first complex stimulation channel from the set of complex stimulation channels that has an associated stimulation efficiency that is below a stimulation efficiency limit is identified. The first complex stimulation channel is combined with an adjacent/neighboring complex stimulation channel to create a combined complex stimulation channel. The combined complex stimulation channel replaces both the first complex stimulation channel and the adjacent complex stimulation channel within the set of complex stimulation channels.

An auditory neural interface device for sound perception by an individual that may be used as a hearing aid. The auditory neural interface device includes a receiver configured to receive sound signals, a processor operably connected to the receiver and configured to encode a received sound signal as a multi-channel neurostimulation signal, and a neurostimulation device operably connected to the processor and configured to apply the multi-channel neurostimulation signal to a neurostimulation electrode of the individual. The neurostimulation signal is configured to directly stimulate afferent sensory neurons of the central nervous system of the individual and thereby to elicit, for each channel of the neurostimulation signal, one or more non-auditory, preferably somatosensory, perceptions in a cortex area of the individual. Each channel of the neurostimulation signal is associated with a different non-auditory perception.

A system for a neurostimulator coupled to electrodes, and a method of providing therapy to a patient using the electrodes implanted within the patient. A target multipole relative to the electrodes is defined. The target multipole is emulated by defining an initial electrical current distribution for the electrodes, such that a first set of active electrodes respectively has electrical current values of a first polarity. Each of the electrical current values of the first polarity is compared to a first threshold value, and at least one of the electrodes in the first active electrode set is zeroed-out based on the comparison. The electrical current value of each of the zeroed-out electrode(s) is redistributed to remaining ones of the electrodes to define a new electrical current distribution for the electrodes. Electrical current is conveyed to the electrodes in accordance with the new electrical current distribution, thereby providing the therapy.

Systems and methods for enhancing muscle function of skeletal muscles in connection with a planned spine surgery intervention in a patient's back are provided. The method includes implanting one or more electrodes in or adjacent to tissue associated with one or more skeletal muscles within a back of a patient, the one or more electrodes in electrical communication with a pulse generator programmed for enhancing muscle function of the one or more skeletal muscles. Electrical stimulation is delivered, according to the programming during a time period associated with the planned spine surgery intervention, from the pulse generator to the tissue associated with the one or more skeletal muscles via the one or more electrodes, thereby improving neuromuscular control system performance of the one or more spine stabilizing muscles in connection with the planned spine surgery intervention to reduce the patient's recovery time associated with the planned spine surgery intervention.

A system for restoring muscle function to the lumbar spine to treat low back pain is provided. The system may include electrodes coupled to an implantable pulse generator (IPG), a handheld activator configured to transfer a stimulation command to the IPG, and an external programmer configured to transfer programming data to the IPG. The stimulation command directs the programmable controller to stimulate the tissue in accordance with the programming data. The system may include a software-based programming system run on a computer such that the treating physician may program and adjust stimulation parameters.

A neuromodulation device generates a therapeutic neuromodulation field to produce a therapeutic effect in therapy-targeted neural tissue, and a priming field to produce a priming effect in priming-targeted neural tissue. The priming effect causes a change in sensitization of the priming-targeted neural tissue to the therapeutic neuromodulation field. The priming field is generated concurrently during generation of the therapeutic neuromodulation field to increase efficacy of the therapeutic effect.

A device and means to decrease the pain associated with cancer biopsies procedures The device uses anesthetic injections and electrical currents of both positive or negative polarity, or alternating current. The device can be incorporated into existing biopsiy devices. Application on breast cancer biopsies and other types of biopsies.

An electrical stimulation system includes an implantable control module configured and arranged for implantation in a body of a patient. The implantable control module includes a processor that generates and delivers electrical stimulation pulses or pulse bursts at a pathological frequency or with a temporal separation between pulses or pulse bursts individually selected based on a pre-determined distribution function based on a pre-selected pathological frequency.