To enhance diffusive mass transfer of small molecules and convective clearance of middle molecules, the present invention provides a cylindrical hemodialyzer which comprises a blood compartment having a packed bundle of hollow fibers in a doughnut configuration on a radial cross-section, and a motorized dialysate compartment comprising a dialysate inlet motor having an external stator and an internal rotor connected to an axial spiral flow converter slidably inserted in a center of the packed bundle of the hollow fibers. The cylindrical hemodialyzer is configured to recirculate dialysate across the packed bundle of the hollow fibers propelled by the dialysate inlet motor. A dialysate outlet motor of the motorized dialysate compartment having an external stator and an internal rotor is configured to drain the dialysate and to control ultrafiltration by said cylindrical hemodialyzer.

A membrane filter apparatus for splitting a feed into filtrate and retentate is provided. The apparatus comprises a body chamber, a feed inlet disposed on the body chamber, a retentate outlet located in the body chamber, a feed distribution tube connected to the feed inlet, and a filter assembly having a filter. The feed distribution tube has a length sufficient to cause the feed to enter the body chamber at a feed distance from the filter assembly of no greater than 50% of a total length of the body chamber. The feed flows across the filter in a direction parallel to a surface of the filter assembly. The filtrate passes through the filter assembly and the retentate flows through the body chamber in a direction antiparallel to the feed flow through the feed distribution tube and out through the retentate outlet.

Devices and techniques may improve the permeate productivity in membrane distillation separation by modifying the feed and/or coolant sides of a membrane distillation module depending on the membrane distillation configuration. The bubbling of a carrier gas through the feed liquid in the feed liquid side of the module can increase the turbulent dissipation rate and/or enhance mass transfer across the membrane pores.

Provided are a porous outflow pipe and an osmosis module comprising same. A porous outflow pipe for forward osmosis or pressure-retarded osmosis, according to one embodiment of the present invention, comprises: a hollow pipe provided with a plurality of first through-holes and second through-holes in the lengthwise direction through which a fluid flows in and out; a bypass pipe arranged concentrically inside the hollow pipe in the lengthwise direction; and a partitioning plate formed along the circumference of the bypass pipe, for preventing mixing of a fluid introduced through the front end side of the hollow pipe and a fluid introduced through the second through-holes.

A disposable cell enrichment kit includes a crossflow filtration device configured to be disposed along a main loop pathway and to receive a process volume containing a biological sample and utilize crossflow filtration, via a micro-porous membrane, to retain a specific cell population in a retentate from the process volume and to remove a permeate including certain biological components from the process volume. The crossflow filtration device includes a laminated filtration unit that includes the micro-porous membrane, a first mating portion, a second mating portion, and a membrane support. The membrane support includes a first plurality of structural features that define a first plurality of openings, wherein the first plurality of structural features are coupled to the micro-porous membrane and provide support to the micro-porous membrane, and the first plurality of openings allow the permeate to flow through them after crossing the micro-porous membrane.

A central tube assembly for a filter cartridge and a manufacturing method for the central tube assembly are provided. The central tube assembly includes a first half-tube defines a first flow passage, and having a first water inlet at an end thereof and a water output hole in a side wall thereof, a filtering membrane bent to form a first membrane layer and a second membrane layer, the first half-tube being disposed between the first membrane layer and the second membrane layer; an input-water filtering net connected to the first half-tube and disposed between the first membrane layer and the second membrane layer, a second half-tube disposed outside of a bending of the filtering membrane, defining a second flow passage, and having a water input hole in a side wall thereof and a first water outlet at an end thereof, and a produced-water filtering net.

A sheet-shaped hollow fiber membrane module includes a casing having a flat shape, the casing including a supply port and a discharge port, and a plurality of hollow fiber membranes accommodated inside the casing. The casing includes a plurality of the supply ports on one main surface of the casing and a plurality of the discharge ports on the other main surface of the casing, at least one of the plurality of the supply ports is closable, and at least one of the plurality of the discharge ports is closable. Each of the plurality of hollow fiber membranes includes a first opening at one end of the hollow fiber membrane and a second opening at the other end of the hollow fiber membrane, and the first opening and the second opening communicate with an outside of the casing and do not communicate with an inside of the casing.

A microfilter, a manufacturing method thereof, and a microfiltration unit for holding the microfilter are provided. The microfilter has: a non-epoxy based microfilm; and a plurality of microholes provided on the surface of the non-epoxy based microfilm and penetrating therethrough via UV laser ablation, wherein the surface of the non-epoxy based microfilm is patterned into predetermined sections for locating isolated targets and quick enumeration.

A fluid processing system may include a flow control cassette comprising at least one interface sensor chamber in fluid communication with at least one of a plurality of separate channels, the at least one interface sensor chamber defined at least in part by a wall, and at least one capacitive sensor disposed on the wall of the at least one interface sensor chamber. The fluid processing system may include, in the alternative or in addition, at least one syringe comprising a wall defining a barrel having a first end and a second end, the barrel having a bore with or without a piston or plunger disposed therein, and at least one capacitive sensor disposed on an outer surface of the wall of the syringe.

A fluid processing system may include a flow control cassette comprising at least one interface sensor chamber in fluid communication with at least one of a plurality of separate channels, the at least one interface sensor chamber defined at least in part by a wall, and at least one capacitive sensor disposed on the wall of the at least one interface sensor chamber. The fluid processing system may include, in the alternative or in addition, at least one syringe comprising a wall defining a barrel having a first end and a second end, the barrel having a bore with or without a piston or plunger disposed therein, and at least one capacitive sensor disposed on an outer surface of the wall of the syringe.