A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

A module comprises a cell stack having a plurality of alternating ion depleting compartments and ion concentrating compartments, an inlet manifold configured to facilitate a flow of fluid into the cell stack, and a first flow distribution system, associated with the inlet manifold, including a first ramp to promote the circulation of the flow of fluid into the cell stack.

Provided are a central tube for a filter cartridge and a filter device having same. The central tube (100) comprises a first half tube (1), a second half tube (2) and a membrane element (3), wherein the first half tube (1) has a first mating surface, and the first mating surface is grooved to form a first flow channel (111); the second half tube (2) has a second mating surface, the second mating surface is grooved to form a second flow channel (21), and the first half tube (1) and the second half tube (2) are butt-jointed to form a hollow, straight tube shape; and the membrane element (3) is arranged between the first half tube (1) and the second half tube (2) and seals the first flow channel (111) and the second flow channel (21), respectively.

A gas separation module includes hollow polymeric fibers held between a pair of tubesheets. The tubesheets are mounted to a core tube, and the distance between the tubesheets is maintained constant. The core tube is formed in telescoping sections, such that the fibers are attached to the tubesheets when the core tube is in its extended position, and the core tube is then collapsed, forming slack in the fibers. The core tube includes two distinct channels, connected to receive permeate and retentate gas streams, and to carry these streams to outlet ports while keeping the streams separate. Because the tubesheets are affixed to the core tube, the tubesheets do not move under the influence of gas pressure in the module. The slack in the fibers compensates for shrinkage of the fibers, prolonging the life of the module.

A means capable of simply and efficiently concentrating a cell suspension. A concentrator has a culture vessel having a first port and a second port, a server bag having a port, a case having a hollow fiber bundle in the internal space, a filtering device having an inlet port, a first outlet port, and a second outlet port, a collection vessel having a port, a liquid supply circuit connected to the first port, the inlet port, and the server bag's port so that flow passages are switchable, a liquid discharge circuit connected to the second port, the first outlet port, the second outlet port, and the collection vessel's port so that flow passages are switchable, a liquid supply mechanism having a switching mechanism, a supply pump, and a discharge pump, and a rotation mechanism rotating the filtering device.

A method for the desalination of water, carried out in one embodiment on the basis of a borehole (4) in permeable coastal land, in which two internal wells (5, 6) are interconnected at the bottom, by means of a membrane packet (9), disposed such that the supply flow provided via the borehole (4) flows in a downward direction by the suction of a motor pump (7) installed at a shallow depth inside the well (5), with an ascending flow, pouring same to the marine outlet and the diluted flow (permeate) drains from the membrane packets (9) to the second well (6), which is hollow and at atmospheric pressure, where a motor pump (8) extracts the permeate for the use thereof, while in another embodiment the membrane packets (15) may be disposed in ducts hanging from a floating platform anchored in the sea or other salty water.

A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

A manufacturing method for a separation membrane element is a manufacturing method for a spiral-wound type separation membrane element including a perforated hollow tube and a laminated body that includes a separation membrane and is wound around the hollow tube. The manufacturing method includes pressing a press member against a portion of the laminated body that is wound around the hollow tube. The pressing presses the press member to satisfy respective relations defined by formulas (1) and (2):

0.1Ps1Pe(1), and

0.1Ps2Pe(2).

The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features.

A membrane contactor for degassing a gas-entrained liquid and to discharge gas-depleted liquid includes: a shell has two ends; a cap closes one shell end; a membrane extends between the shell ends and is enclosed within the shell; a first center tube discharges the gas-entrained liquid into the membrane; a second center tube discharges the gas-depleted liquid from the contactor; and one tube surrounds the other tube. The membrane may be a flat sheet membrane or a hollow fiber membrane. The cap has an in let in fluid communication with the first center tube and an outlet in fluid communication with the second center tube. A baffle may be located within the membrane between the shell ends.