Methods and devices for producing a population of liposomes are provided. Aspects of the methods include applying a centrifugal force to a suspension of liposomes in a manner sufficient to pass the liposomes through a porous membrane to produce a population of liposomes. Aspects of the invention further include devices, systems and kits useful for performing the methods.

The present disclosure relates to methods and systems for the continuous production of recombinant proteins. In particular embodiments, the disclosure relates to methods and systems using capture chromatography, post-capture chromatography, virus filtration, and ultrafiltration/diafiltration for the continuous production of recombinant proteins.

A platform has a filter system with a first set of filter modules and a second set of filter modules that is different from the first set of filter modules. Each set of filter modules includes an inflow channel and an outflow channel. A fluid inlet is connected to the first set of filter modules, a fluid outlet is connected to the second set of filter modules, and a separation interface separates the first and second sets of filter modules. The separation interface has a first interface channel to connect to the module outflow channel of the first set of filter modules, and a second interface channel to connect to the module inflow channel of the second set of filter modules. The filter system receives fluid through the fluid inlet and, after the fluid has passed through each set of filter modules, discharges the fluid through the fluid outlet.

Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.

The present invention relates to a filtration system comprising a cabinet, a filtration device having a filtrate or retentate vessel arranged outside the cabinet, and a weighing device that is configured to weigh the filtrate or retentate vessel. The weighing device can be arranged inside an enclosure and the enclosure can be arranged inside the cabinet.

The invention relates to a method for the processing of protein-containing suspensions or solutions, for example for concentrating or purifying the protein-containing particles or dissolved protein-containing substance contained in the suspensions or solutions, wherein the protein-containing suspensions or solutions are filtered by means of a filter module and the protein-containing particles or dissolved protein-containing substance retained in the filter module are conveyed out of the filter module by means of a backwashing fluid.

A filter module (10) has a housing (12) which is subdivided by a membrane filter (14) into an inlet chamber (16), which is connected to an inlet connecting piece (22) arranged rigidly on the housing (12), and an outlet chamber (18), which has a filtrate outlet (20). The inlet connecting piece has two connectors, specifically a first connector (26) and a second connector (28), which connect selectively and fluidically to the inlet chamber with a 3-way valve (24) integrated into the inlet connecting piece. The valve has a first entry, which is connected to the first connector, a second entry, which is connected to the second connector, and an exit, which is connected to the inlet chamber. The first connector is configured as an adapter for outwardly sealed coupling of a culture medium bottle (30), which coupling permits a gravity-driven exchange of liquid with the first entry of the valve.

The present invention relates to a method for treating an aqueous liquid comprising oil droplets and a surfactant and/or a base. For this method, a pore size threshold of a filter is determined taking into account the interfacial tension between the oil droplets and the water, and a filter is selected whose pore size is less than or equal to this threshold for filtration of the aqueous liquid.

Methods and devices for producing a population of liposomes are provided. Aspects of the methods include applying a centrifugal force to a suspension of liposomes in a manner sufficient to pass the liposomes through a porous membrane to produce a population of liposomes. Aspects of the invention further include devices, systems and kits useful for performing the methods.

Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.