Processes and systems for filtering a liquid sample are provided. Batches of a liquid sample can be routed to two or more cycling tanks (e.g., first and second cycling tanks). Upon filling a first cycling tank, a first batch of the liquid sample can be routed to a filtration assembly by a continuous diafiltration process that includes routing produced retentate back to the first cycling tank or to a collection vessel. Upon filling a second cycling tank, a second batch of the liquid sample is routed to the filtration assembly by a continuous diafiltration process that includes routing produced retentate back to the second cycling tank or to the collection vessel. The filling and continuous diafiltration of batches of the liquid sample continues to alternate between the two or more cycling tanks until a total product volume is processed.

The present disclosure is directed to filtering technologies that combine elements of continuous and batch NF/RO based on the constraints of the end-user facility to achieve a target balance between, for instance, recovery and power consumption, and to reduce long term operating cost of a plant. A method for extending batch operation into a second induction period with antiscalant injection is also disclosed herein, with the second induction period allowing for yet higher water recovery.

The present disclosure is directed to filtering technologies that combine elements of continuous and batch NF/RO based on the constraints of the end-user facility to achieve a target balance between, for instance, recovery and power consumption, and to reduce long term operating cost of a plant. A method for extending batch operation into a second induction period with antiscalant injection is also disclosed herein, with the second induction period allowing for yet higher water recovery.

A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.

The present technology provides micro fabricated filtration devices, methods of making such devices, and uses for microfabricated filtration devices. The devices may allow diffusion to occur between two fluids with improved transport resistance characteristics as compared to conventional filtration devices. The devices may include a compound structure that includes a porous membrane overlying a support structure. The support structure may define a cavity and a plurality of recesses formed in a way that can allow modified convective flow of a first fluid to provide improved diffusive transport between the first fluid and a second fluid through the membrane.

Described herein are crosslinked graphene oxide based composite membranes that provide selective resistance for gases while providing water vapor permeability. Such composite membranes have a high water/air selectivity in permeability. The methods for making such membranes, and using the membranes for dehydrating or removing water vapor from gases are also described.

The present disclosure pertains to filtration methods comprising: passing a first fluid that comprises cells, cell debris and targeted product produced by the cells through a first filter thereby separating the first fluid into a first retentate comprising cells and a first permeate comprising targeted product and cell debris; combining resin beads having affinity for targeted product with the first permeate to form a second fluid containing resin beads with bound target product and cell debris; passing the second fluid through a second filter thereby separating the second fluid into a second retentate comprising resin beads with bound target product and a second permeate comprising cell debris; combining an elution buffer with the second retentate to form a third fluid that comprises a mixture of resin beads and unbound targeted product; and passing the third fluid through a third filter thereby separating resin beads from targeted product.

An inventive apparatus for closed circuit batch-RO desalination comprising a RO-skid with membrane elements and circulation means for the recycling of RO concentrate through membranes and a designed hydraulic-arm with a disc separating between a section of pressurized hydraulic fluid created by a high pressure hydraulic pump under fixed flow and variable pressure conditions and a section of RO recycled concentrates. The batch desalination sequence is completed when the entire hydraulic-arm volume is filled with hydraulic fluid and thereafter, desalination is stopped, said apparatus decompressed, brine removed and hydraulic-arm recharged with fresh feed before the initiation of a new batch sequence. The inventive apparatus enables RO desalination under the lowest energy and highest recovery prospects not possible by any other RO technique.

The devices, systems, and methods of the present disclosure are generally directed to using an increase in gas pressure (e.g., through an increase in heat) to move an actuator that at least partially defines a volume containing a feed fluid in fluid communication with a membrane. As the increase in gas pressure moves the actuator, pressure on the feed fluid in the volume may increase beyond a threshold pressure sufficient to move the feed fluid through the membrane. Movement of the feed fluid through the membrane may reduce a volumetric concentration of one or more components of the feed fluid to form a permeate. For example, the increase in pressure may drive the actuator to increase pressure on salt-water in the volume and, ultimately, move the salt-water through the membrane to form the permeate as part of a reverse osmosis process achieved without the use of a mechanical pump.

The present technology provides micro fabricated filtration devices, methods of making such devices, and uses for microfabricated filtration devices. The devices may allow diffusion to occur between two fluids with improved transport resistance characteristics as compared to conventional filtration devices. The devices may include a compound structure that includes a porous membrane overlying a support structure. The support structure may define a cavity and a plurality of recesses formed in a way that can allow modified convective flow of a first fluid to provide improved diffusive transport between the first fluid and a second fluid through the membrane.