A dispensing container and adapter system for use with a planetary mixer is disclosed. The dispensing container has a longitudinal axis and a transverse axis. The dispensing container may include a nozzle and a removable cap to cover the nozzle. The removable cap may have a first width dimension measured along the transverse axis. The dispensing container may include a body having a second width dimension measured along the transverse axis. An adapter may receive the dispensing container. The adapter may include a cavity to receive the removable cap. The cavity may have a cavity width that exceeds the first width dimension. The adapter may also include a recess for receiving a portion of the dispensing container. The recess may extend from the cavity. At least a portion of the recess may have a width dimension smaller than both the first width dimension and the second width dimension.

A rotation mixer including a housing, a drive unit coupled to the housing, a carriage mounted on the drive unit for rotation relative to the housing, and a basket mounted for rotation relative to the carriage. The basket receives material to be mixed. The carriage includes an arm and a drive line coupled to the arm. The arm is mounted on the drive unit for rotation about a first axis relative to the housing, and the drive line converts rotation of the arm into rotation of the basket about a second axis relative to the arm during use of the rotation mixer. The drive line illustratively includes a belt and plurality of pulleys upon which the belt travels in a continuous loop, the belt engaging with a gear on the basket to cause rotation of the basket.

Mixing devices and associated methods are described herein. Various embodiments of mixing devices can comprise a plate configured to rotate about a longitudinal axis and a plurality of enclosures coupled to the plate. The enclosures can each include (a) at least one sidewall that defines an oblique angle with the plate and (b) a chamber configured to receive a media and a fluid. The enclosures can be fluidly coupled to a fluid source for receiving the fluid in the chambers. When the plate is rotated, the enclosures revolve about the longitudinal axis to mix the media with the fluid in the chambers.

The present disclosure relates to a combination including an outer container for mounting in a container holder of a planetary mixer, the outer container receiving an inner container arrangement allowing to mix ingredients into the inner container arrangement with the planetary mixer to produce in the inner container arrangement a pharmaceutical composition. The outer container may include a body having an outer wall and an inner wall. The inner wall may delimit a central cavity for nestably receiving the inner container arrangement. The outer container may also include a slot on the inner wall. The slot may engage with a protrusion on the inner container arrangement when the inner container arrangement is received in the central cavity to inhibit rotational motion of the inner container arrangement within the outer container, induced as a result of combined rotation and revolution imparted to the outer container by the planetary mixer.

A rotary machine for acting on a process fluid includes an impeller, a shaft, a drive, a seal and a flush casing. The impeller acts on the process fluid and is mounted on the shaft. The drive is connected to the shaft and rotates the shaft and the impeller about an axial direction. The seal has a sealing element sealing the shaft during rotation of the shaft. The flush casing receives a flushing fluid for flushing the sealing element, and delimits an annular flush chamber extending about the sealing element. The flush casing includes a bushing surrounding the sealing element and delimits a radial leakage gap arranged between the sealing element and the bushing. The bushing delimits an axial leakage gap between the impeller and the bushing, and the width of the axial leakage gap in the axial direction is adjustable.

The present disclosure relates to a system and process for manufacturing patient personalized pharmaceutical compositions using superimposed revolution and rotation movements for dispersing, milling, melting, and/or de-aerating, where these superimposed revolution and rotation movements can be carried out in a single device in a pharmacy setting.

The present disclosure relates to a system and process for manufacturing patient personalized pharmaceutical compositions using superimposed revolution and rotation movements for dispersing, milling, melting, and/or de-aerating, where these superimposed revolution and rotation movements can be carried out in a single device in a pharmacy setting.

A tumbler crystallizer for crystallizing pelleted, tacky, polymeric materials includes a housing for rotatably supporting a removable paneled drum on rollers. The removable panels may be made of a transparent, heat-insulating material. The drum receives a flow of hot pellets through an inlet chute, and a tumbling action of the drum and internal agitators keeps the pellets in motion relative to each other to prevent agglomeration until they reach a desired level of crystallinity and are no longer tacky. Baffle plates are provided at intervals along the length of the drum to slow the flow of pellets therethrough to increase residence time. Damper plates are provided near the exit end of the drum to aid in building a bed of pellets within the drum, and also to control residence time of the pellets within the drum.

The disclosure provides methods and compositions for providing shatter formulations taking the form of crystalline polymorphs, where methods of preparation include preparing tetrahydrocannabinol acid (THCA) powder followed by decarboxylating THCA and removal of terpenes.

A burner has a housing on which a combustion tube is arranged, wherein the combustion tube has an opening at the end averted from the housing, wherein a mixing element is provided in the combustion tube, and the space between the mixing element and the opening forms a combustion chamber, wherein the housing has at least two mutually separate channels which open out in the mixing element, wherein gases flow through the channels and the mixing element, and mixing of the gases takes place for the first time in a combustion chamber, wherein the mixing element is produced in an additive manufacturing process and has at least two separate intermediate channels which branch in the direction of the combustion chamber in a flow direction.