Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

Bioreactor bags formed from sheet materials are disclosed. The bioreactor bags include an opening which is openable and recloseable in a fluid tight manner for providing an opening for insertion of solid materials into the bag.

A cost-effective, single use bag or container is provided for storing biological substances that incorporates on its inner wall an electronic device that is configured to measure physiological and/or physical parameters of the enclosed biological substances, such as source history, identification, demographics, time stamping, temperature, pH, conductivity, glucose, O.sub.2, CO.sub.2 levels etc. The electronic device of the disclosed bag comprises a sensor configured to measure physiological and/or physical parameters of the biological substances enclosed within the bag, and a radio-frequency (RF) device communicably coupled to the sensor and configured to: (a) acquire from the sensor data associated with the measured parameters, (b) store the acquired sensor data in nonvolatile memory, and (c) communicate the stored data wirelessly to a RF reader.

An apparatus for and method of enabling enhanced, selective agitation of liquid containing a solid-phase reagent. The apparatus includes at least one liquid-bearing container, a circular tray, and a motor. The liquid-bearing container(s) includes at least one internal baffle that imparts turbulent agitation to the liquid when flowing from one end of the container to an opposite end. The circular tray is adapted for selective rotation about a vertical axis of rotation. The rotary circular tray assembly includes container-receiving stations that selectively retain a respective liquid-bearing container in an inclined or pitched orientation with respect to a horizontal plane. The motor creates centrifugal force, which causes liquid in the container(s) to travel from the first end of the container to the second end of the container via the internal baffle(s), agitating the liquid and the solid-phase portions of the reagent. When gravitational force exceeds the centrifugal force, liquid in the container(s) travels from the second end of the container to the first end of the container via the internal baffle(s), again agitating the liquid and the solid-phase portions of the reagent.

Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

A bottle warming apparatus is disclosed that combines heating and agitating of a bottle and its contents in order to achieve even warming, as well as, mixing the contents of the bottle.

A mixing device and methods of utilizing the same. More specifically, embodiments of the present disclosure relate to a mixing device that may be used to make medications and specialized pharmaceuticals for administration via intrathecal infusion therapy, or the like. A mixing device may comprise an upper chamber, a lower chamber having four compartments for accepting an amount of medication, wherein the upper chamber and the lower chamber may be coupled and may be used to mix and make medication accessible via a Luer Lock adapter, termination, or the like, wherein the device is in compliance with USP 797 standards.

Disclosed is a process photometer arrangement (10) with a photometric cuvette unit (20) comprising a cuvette body (24) defining a cuvette cavity (25) and a combined sample inlet/outlet opening (34), a photometer light inlet window (60) and a photometer light outlet window (62). The cuvette body (24) is movably supported by a cuvette body support element (88) and the cuvette unit (20) is provided with a cuvette vibration device (80) for vibrating the cuvette body (24) to thereby quickly and homogenously mix a liquid sample volume (31) within the cuvette cavity (25) without any separate mixing element within the cuvette cavity. This allows a short mixing action within a microfluidic cuvette.

A collection bottle that emits light once the lid of the bottle is rotated to its complete closed position is disclosed. An annular chamber concentric to the inner chamber of the collection bottle contains a dye such as fluorophor, a base catalyst, and diphenyl oxalate. A containment device is disposed in the annular chamber. The containment device holds one or more glass or other fragile material encasing vials containing hydrogen peroxide. The containment device is disposed in the vicinity of the bottle screw threads such that when the lid is completely screwed onto the collection bottle, a detent that is disposed above the superior lid screw thread compresses the exterior wall of the annular chamber and containment device, causing rupture of the vial(s) and allowing the hydrogen peroxide disposed therein to mix with the dye, base catalyst and diphenyl oxalate in the annular chamber. The subsequent chemical reaction causes the emission of light, visually indicating full closure of the lid on the collection bottle.