The present invention provides a device and a method for automated liquid exchange in a horizontally rotating container that may be applied in automated sample treatment by using chemical solutions, in sequential order. Such applications include biomolecule staining on solid support or fixed samples such as western blot or tissue slice processing. Such sequential chemical reactions are usually performed on flat surfaces. Alternatively, these reactions can be completed with much less volume of reagents in horizontally rotating containers. Yet, it is difficult to automate these processes in rotating containers since the required tubing would twist due to the continuous rotation of the container. The present invention solves the problem of twisting of tubing by leading them through a stationary tubing carrier that passes through the rotating container. Hence, the rotation of the tubing, and therefore twisting, is avoided, thus enabling automated liquid exchange of various chemical solutions in rotating containers.

A bottle warming apparatus is disclosed that combines heating and agitating of a bottle and its contents in order to achieve even warming, as well as, mixing the contents of the bottle.

A bottle warming apparatus is disclosed that combines heating and agitating of a bottle and its contents in order to achieve even warming, as well as, mixing the contents of the bottle.

A method of heating and mixing contents is disclosed that combines heating and agitating of a bottle and its contents in order to achieve even warming, as well as, mixing the contents of the bottle.

A method of heating and mixing contents is disclosed that combines heating and agitating of a bottle and its contents in order to achieve even warming, as well as, mixing the contents of the bottle.

A mixing device comprising a multi-element spring system in which an eccentric load, coupled to a rotor of a motor, is located towards a first end of a first beam realising a backbone for the mixing device. One or more connections interconnect the backbone respectively to one or more other beams to produce the multi-element spring system. A load, such as a vial or other container in which is located a diluent, is located remotely from the motor. As such, the spring system supports two independent but complementary eccentric load generating subsystems arising from, respectively, the controlled rotation of the rotor (and its eccentric load) and then, in response to rotation of the connected eccentric load on the rotor, swirling of the diluent in the vial/container. Both these eccentric loads contribute to a complex multidirectional flexing of the multi-element spring system relative to a fixed anchor point, with this multidirectional flexing working to induce a swirling motion in the contents of the container.

A mixing device comprising a multi-element spring system in which an eccentric load, coupled to a rotor of a motor, is located towards a first end of a first beam realising a backbone for the mixing device. One or more connections interconnect the backbone respectively to one or more other beams to produce the multi-element spring system. A load, such as a vial or other container in which is located a diluent, is located remotely from the motor. As such, the spring system supports two independent but complementary eccentric load generating subsystems arising from, respectively, the controlled rotation of the rotor (and its eccentric load) and then, in response to rotation of the connected eccentric load on the rotor, swirling of the diluent in the vial/container. Both these eccentric loads contribute to a complex multidirectional flexing of the multi-element spring system relative to a fixed anchor point, with this multidirectional flexing working to induce a swirling motion in the contents of the container.

A mixing device of FIG. 1b comprises a multi-element spring system in which an eccentric load, coupled to a rotor of a motor, is located towards a first end of a first beam realising a backbone for the mixing device. One or more connections interconnect the backbone respectively to one or more other beams to produce the multi-element spring system. A load, such as a vial or other container in which is located a diluent, is located remotely from the motor. As such, the spring system supports two independent but complementary eccentric load generating subsystems arising from, respectively, the controlled rotation of the rotor (and its eccentric load) and then, in response to rotation of the connected eccentric load on the rotor, swirling of the diluent in the vial/container. Both these eccentric loads contribute to a complex multidirectional flexing of the multi-element spring system [relative to a fixed anchor point], with this multidirectional flexing working to induce a swirling motion in the contents of the container.

A mixing device of FIG. 1b comprises a multi-element spring system in which an eccentric load, coupled to a rotor of a motor, is located towards a first end of a first beam realising a backbone for the mixing device. One or more connections interconnect the backbone respectively to one or more other beams to produce the multi-element spring system. A load, such as a vial or other container in which is located a diluent, is located remotely from the motor. As such, the spring system supports two independent but complementary eccentric load generating subsystems arising from, respectively, the controlled rotation of the rotor (and its eccentric load) and then, in response to rotation of the connected eccentric load on the rotor, swirling of the diluent in the vial/container. Both these eccentric loads contribute to a complex multidirectional flexing of the multi-element spring system [relative to a fixed anchor point], with this multidirectional flexing working to induce a swirling motion in the contents of the container.

A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at at least two of the plurality of bulk material filling stations.