A microfluidic sample processing device, capable of automatically processing a microfluidic sample, comprises: a tray apparatus, for accommodating a reagent and a chip clamp for mounting a microfluidic chip; a mechanical arm, having a connecting head for connecting the chip clamp, a gas flow channel for communicating with an inner cavity of the chip clamp being arranged in the connecting head; a negative pressure suction apparatus, for providing negative pressure to the gas flow channel of the connecting head; a lifting apparatus, for driving the connecting head to rise and fall; and a translation apparatus, for driving the connecting head to move to above the chip clamp or above the reagent; wherein, the tray apparatus is positioned below the mechanical arm, and the mechanical arm is arranged on the translation apparatus and is connected to the lifting apparatus.

A container for a reactive product including a container body having a neck delimiting a neck opening; a closure member comprising a puncturable closure membrane which tightly seals off the neck opening; a suction tube located in the container body and comprising a first end portion attached to the closure member and a second end portion extending in the proximity of the bottom of the container body; and a cap attached to the neck and comprising a passage opening which is located facing the puncturable closure membrane and the first end portion of the suction tube, the cap being configured so as to enable the penetration of a sampling needle through the passage opening and the puncturable closure membrane such that the sampling needle is fluidly connected to the suction tube, and so as to enable the penetration of a venting needle through the passage opening and the puncturable closure membrane such that the venting needle is fluidly connected to an internal volume of the container body.

An apparatus including a fluidic input and a die including a microfluidic chamber, may receive a biologic sample. The microfluidic chamber may include a foyer to contain a portion of the biologic sample, and an inlet impedance-based sensor to detect passage of a cell of the biologic sample into the foyer. A target nozzle may eject a first volume, corresponding with a target concentration of cells of the biologic sample. A spittoon nozzle may eject a second volume of the portion of the biologic sample into a spittoon location. An output impedance-based sensor may be disposed within a threshold distance of the target nozzle to detect passage of a cell of the biologic sample into the target nozzle. Moreover, the apparatus may include circuitry to control firing of the target nozzle and the spittoon nozzle based on signals received from the inlet impedance-based sensor and the output impedance-based sensor.

The invention relates to an arrangement for preparing a plurality of samples for an analytical method, comprising a carousel with a solid housing and moveable receiving parts for the sample containers; a control for controlling the receiving parts in the carousel; and a sample receiving device for providing the sample for the analytical method. Said arrangement is characterized in that one or more stations for preparing samples are provided on the carousel, the receiving parts for the sample containers of the carousel can be positioned on said stations. Said arrangement also comprises a centrifuge with pairs of opposite lying receiving parts provided for the sample containers, and said receiving parts are arranged such that they can move on the centrifuge for the sample holder such that a transfer of a sample holder between a receiving part in the carousel and a receiving part in the centrifuge can be carried out. The control takes place by the same control which is also provided for controlling the carousel.

The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.

The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.

A laboratory instrument for processing a sample and a method for automatic surveillance of at least one pipetting procedure of at least one laboratory instrument for processing a sample are disclosed. The laboratory instrument includes at least one pipetting device with at least one pipetting head configured for being coupled to a plurality of pipetting tips. The laboratory instrument further includes a compartment configured for receiving, storing, and/or releasing at least one sample holder. The pipetting device is configured for performing at least one pipetting procedure on the sample holder and the laboratory instrument includes at least one sensor unit configured for gravimetric measuring of the sample holder.

A pipetting device, a system comprising the pipetting device, and a system for handling liquids and providing a pipetting device, the pipetting device comprising a housing with two parallel flat surfaces with a maximal distance of 17.5 mm between them accommodating a Z-shaft mounted in a guiding and connected to a Z-drive for actuating the Z-shaft; and a Y-drive which is connected to the housing and comprises a Y-gear wheel that is arranged next to an opening in the housing

Disclosed are a droplet generation method, system and application thereof. The method breaks through the limitation that the existing nanoliter scale droplet generation technology must use micro-channels below 0.1 mm, and can realize the preparation of small-volume uniform droplets at a reduced cost. The system includes a droplet generation device and a droplet receiver, the droplet generation device includes an accommodating cavity with a variable volume, a control mechanism for controlling the volume of the accommodating cavity to change periodically, and a droplet generation tube, which has a wide range of applications in clinical diagnosis, gene expression analysis, microorganism detection and other fields.

A pipetting device includes pipetting unit(s), a guide assembly with at least one guide rail on which the pipetting unit(s) is guided in order to be moved along a movement axis, and a linear drive assembly, by which the pipetting unit(s) can be driven in order to be moved along the movement axis. The linear drive device has a stationary stator, and the at least one pipetting unit forms a linear drive assembly rotor which can be moved along the movement axis relative to the stator. The pipetting device also has at least two rotor magnet assemblies which interact with the same common stator magnet assembly so as to generate a drive force and which are arranged at a distance from one another along a spacing axis that is orthogonal to the movement axis. The common stator magnet assembly is located between the at least two rotor magnet assemblies.