B01L9/52

METHODS AND SYSTEMS FOR SLIDE PROCESSING
20230160793 · 2023-05-25 ·

Various examples of systems and methods are provided for slide processing. In one example, among others, a system for processing microscope slides includes a slide positioner that can adjust a position of a slide and a slide treatment system that can dispense a micro stream of a fluid at a location on the slide when the slide is positioned beneath a jet nozzle of the slide treatment system. The system can include a slide sled that can align a smearing slide with a surface of the slide including a fluid sample is disposed, and support the smearing slide at a predefined angle with respect to the surface of the slide. In another example, a method includes obtaining a slide including a sample disposed on a surface, positioning the slide below to a jet nozzle, and dispensing a micro stream of a fluid onto the sample using the jet nozzle.

SYSTEM AND METHOD FOR AUTOMATED SINGLE CELL PROCESSING

A system and method for automated single cell capture and processing is described, where the system includes a deck supporting and positioning a set of sample processing elements; a gantry for actuating tools for interactions with the set of sample processing elements supported by the deck; and a base supporting various processing subsystems and a control subsystems in communication with the processing subsystems. The system can automatically execute workflows associated with single cell processing, including mRNA capture, cDNA synthesis, protein-associated assays, and library preparation, for next generation sequencing.

Object picking apparatus with imaging-based locating of pipette tip

An object such as a cell colony may be picked from a plurality of objects by acquiring an image of the objects and an image of a pipette tip. The image of the objects is analyzed to select an object of interest. The selected object is associated with a coordinate position. Based on the coordinate position, the pipette tip is positioned over the selected object. An image of the pipette tip is then acquired and analyzed. The pipette tip is associated with a coordinate position. A positional error between the coordinate position of the selected object and the coordinate position of the pipette tip is determined. Based on the positional error, the pipette tip and/or a sample holder supporting the objects is moved to align the pipette tip over the selected object, by matching the coordinate position of the pipette tip with the coordinate position of the selected object.

Laboratory device

A device for supporting a laboratory object is provided. The device may comprise a body extending about and defining an opening. The body may be positioned in a customized orientation selected from a plurality of orientations. The device may include a first support defined by the body and configured to contact a surface when the body is in a first orientation. The device may include a second support coupled to the first support. The second support may be configured to contact the surface when the body is in a second orientation.

SAMPLE COLLECTION APPARATUS AND METHOD FOR PREPARING A PLURALITY OF LIQUID SAMPLES FOR SAMPLE PROCESSING
20220334091 · 2022-10-20 ·

A sample collection apparatus, being configured for preparing a plurality of liquid samples for a sample processing, includes a collection device including a plurality of collection vessels being configured for accommodating the liquid samples and for providing the liquid samples for the sample processing, wherein the sample collection apparatus is shaped for positioning the collection device directly in a carousel of an autosampler apparatus, in particular a liquid chromatography autosampler apparatus. Preferably, a holder device is provided which is configured for holding the collection device during collecting the liquid samples and during providing the liquid samples for the sample processing, and the holder device is shaped for positioning the holder device with the collection device directly in the carousel of the autosampler apparatus. Furthermore, a sample preparation apparatus including the sample collection apparatus and a sample collection method are described.

SAMPLE ANALYZING METHOD AND SAMPLE PREPARING METHOD
20220334140 · 2022-10-20 ·

A sample analyzing method and a sample preparing method are provided. The sample analyzing method includes a sample preparing step, a placing step, and an analyzing step. The sample preparing step includes an obtaining step implemented by obtaining an identification information; and a marking and placing step implemented by placing a sample carrying component having a sample disposed thereon into a marking equipment, allowing the marking equipment to utilize the identification information to form an identification structure on the sample carrying component, and placing the sample carrying component into one of the accommodating slots according to the identification information. The placing step is implemented by taking out the sample carrying component from one of the accommodating slots and placing the sample carrying component into an electron microscope equipment. The analyzing step is implemented by utilizing the electron microscope equipment to photograph the sample to generate an analyzation image.

PORTABLE RT-PCR DEVICE AND RT-PCR MEASUREMENT METHOD USING SAME
20230070652 · 2023-03-09 · ·

The present disclosure relates to a portable RT-PCR device and an RT-PCR measurement method that uses the portable RT-PCR device. The portable RT-PCR device includes: a base unit in which a mounting space is formed; a plurality of lower heating units mounted in the mounting space in the base unit; a lower optical measurement unit mounted in the base unit and arranged in a different position than the plurality of lower heating units and providing measurement light or receiving the measurement light; and a chamber assembly including a plurality of chambers that are seated on the plurality of lower heating units and the lower optical measurement unit, respectively, each chamber being provided in such a manner to be movable from one of the plurality of lower heating units to other one of the plurality of lower heating units or to the lower optical measurement unit, wherein each of the plurality of chambers includes: a chamber body for accommodating a chamber unit in which a specimen-unit accommodation space inside which a specimen unit is accommodated is formed; wherein the chamber unit includes: a chamber unit body in which the specimen-unit accommodation space is formed; and a cap unit covering the specimen-unit accommodation space in the chamber unit body from above, and wherein the specimen unit has an aspect ratio, that is, a height-to-width ratio, which is greater than 0 and smaller than 1.

Method and apparatus for handling slides
11465151 · 2022-10-11 ·

The present disclosure provides apparatus and methods for handling slides. The apparatus includes a carrier comprising a retention hole and a cartridge having a case coupled to one or more separators that together define a plurality of compartments each configured to accept the carrier. At least one of the separators comprises a guide hole, with all guide holes are disposed on a first axis. The retention hole of the carrier is aligned with the first axis when the carrier is disposed in a seated position within one of the compartments. The cartridge also comprises a plurality of spacers each partially disposed within at least one of the guide holes.

TEST STRIP HOLDER AND TEST STRIP DISCHARGING MECHANISM
20230152237 · 2023-05-18 · ·

A test strip holder includes: a holding member at which at least a portion of a lower side of an inner periphery is a cylindrical surface having a cylindrical shape, and at whose interior a test strip is held, and at which a direction of an imaginary central axis of the cylindrical surface is a horizontal direction or a direction inclined with respect to a vertical direction; an opening portion provided in an outer surface of the holding member; a sorting member rotating at an interior of the holding member around a rotation axis that coincides with the central axis; a pushing piece projecting out from a distal end edge, which is parallel to the central axis, at the sorting member in a direction of rotation of the sorting member; and a sorting piece projecting out from a distal end of the pushing piece toward the cylindrical surface.

TEST STRIP CONTAINER AND TEST STRIP DISCHARGING MECHANISM
20230152299 · 2023-05-18 · ·

A test strip container includes: an accommodating member in which a test strip is accommodated; a moving member moving the test strip therein; a door member opening and closing at a side surface of the accommodating member to discharge the test strip out of the accommodating member, and cutting the interior and the exterior of the accommodating member off from each other when closed; a door accommodating portion covering the door member, in which the door member can open and close; and a discharge opening cutting the interior and an exterior of the door accommodating portion off from each other when closed, and is provided at the door accommodating portion so as to open and close to discharge the test strip to the exterior of the door accommodating portion, the discharge opening being able to open when the accommodating member is closed by the door member.