B03C2201/18

Equipment and procedure for culturing, separating, and genetically modifying donor cells for reinfusion into a patient

The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

Magnetic baffle insert for use with a basket strainer

A basket strainer insert having a body with one or more magnets disposed therein. The basket strainer insert includes a baffle that is removable. The movement of withdrawing the baffle from the body allows magnetic debris to be removed. A baffle may be disposed at the center of the elongate intermediate portion of the body. The baffle may comprise a collar and two or more symmetrical lobes, each lobe comprising an upper portion and a lower portion. Alternatively, the baffle may be a hollow shape with a plurality of apertures.

SYSTEMS AND METHODS FOR BEAD-BASED ASSAYS IN FERROFLUIDS
20170285060 · 2017-10-05 ·

Some embodiments of the present disclosure are directed to systems and methods for separating, directing, and/or extracting a target molecule from a mix of molecules and may comprise a plurality of non-magnetic beads suspended in a ferro fluid, where the non-magnetic beads may be functionalized with at least one predetermined first molecule configured to bind with a target particle. A microfluidic device may be included which may comprise at least one microfluidic channel, the device configured to dynamically and/or statically receive an amount of the mix. Magnetic field means may be included and may be configured to apply a magnetic field to at least a portion of the at least one channel to exert an indirect force on the non-magnetic heads in the ferro fluid mix, and separate the non-magnetic beads from the ferrofluid. The beads may then be directed to at least one receptor region. At least one outlet may be provided which is arranged to be in communication with the at least one microfluidic channel, the at least one outlet may be configured to receive and extract the separated non-magnetic beads from the ferrofluid.

SOLENOID VALVE
20170282191 · 2017-10-05 ·

A solenoid valve includes: a magnetic force generating coil generating an electromagnetic force; a valve spool reciprocated depending on an electromagnetic force generated from the magnetic force generating coil; a holder having the valve spool inserted into a hollow portion of the holder and forming a plurality of ports opened and closed depending on the reciprocating motion of the valve spool; a foreign material collecting coil collecting a foreign material when power is applied to the magnetic force generating coil to serve as an electromagnet; and a foreign material outlet port formed in the holder and discharging the foreign material collected in the foreign material collecting coil when the supply of power to the foreign material collecting coil is released to outside.

NUCLEIC ACID-BINDING SOLID-PHASE CARRIER AND NUCLEIC ACID EXTRACTION METHOD

A nucleic acid-binding solid-phase carrier includes a magnetic particle of an amorphous metal containing Fe, Cr, Si, and B, and a silicon oxide film provided on the surface of the magnetic particle.

SOLENOID VALVE
20170284558 · 2017-10-05 · ·

A solenoid valve may include a magnetic force generating coil applied with power to generate an electromagnetic force, a valve spool disposed to reciprocate depending on the electromagnetic force generated from the magnetic force generating coil, a holder including a hollow into which the valve spool inserted, the holder forming a plurality of ports to be opened and closed depending on the reciprocating of the valve spool, and a permanent magnet disposed to enclose the hollow of the holder.

BLOOD PURIFICATION DEVICE AND PURIFICATION METHOD OF BLOOD

A blood purification device or the like capable of confirming that magnetic particles have been separated and removed from blood. A blood purification device includes a main flow channel configured to allow blood flows; a magnetic extraction unit (magnetic extraction means) to collect magnetic particles with a magnetic force, the magnetic particles being contained in blood; and one or more magnetic sensor configured to be capable of detecting a presence of the magnetic particles in blood. Each of the magnetic particles has, on at least a part of its outer circumferential portion, a modified part being modified with a separation-target capturing material which is capable of capturing a specific substance to be separated in the blood.

MATERIAL FEED PROCESS AND ASSEMBLY FOR A ROTARY MAGNETIC SEPARATOR
20220048042 · 2022-02-17 ·

The invention provides a material feed process for magnetically separating magnetic and non-magnetic particles from a material feed by means of a magnetic roller separator wherein the process is characterised therein that particle separation is independent of centrifugal force, and where the process can equally well be applied to both wet and dry particle separation. The process specifically provides feeding the particles at an incident zone above the horizontal axis centre line, and separating the magnetic and non-magnetic particles at opposite rotational sides of the roller.

IMPROVEMENT OF CONCENTRATE QUALITY

The present invention relates to a process for the separation of at least one valuable matter containing material from a dispersion comprising said at least one valuable matter containing material and at least one second material. The process according to the present invention comprises at least the steps (A) to (E) and the optional steps (F) to (H) which are described herein.

DEVICE FOR NUCLEIC ACID EXTRACTION USING MAGNETIC BEAD METHOD
20170275614 · 2017-09-28 ·

The present invention provides a device for nucleic acid extraction using a magnetic bead method. The device includes a disc turntable, an arc arch bridge base, a supporting column, and a magnet structural unit and a sample reaction unit both arranged on the disc turntable. The disc turntable includes a top plate; the arc arch bridge base includes a bottom plate arranged at the lowermost portion and an arc supporting plate arranged on the bottom plate, and the arc supporting plate corresponds to the guide rod insertion holes in position in a radial direction of the disc, and the arc supporting plate includes raised regions used for jacking up a guide rod and a magnet and groove regions used for allowing the guide rod and the magnet to fall. The device provided by the present invention can realize the automatic nucleic acid extraction in a stream-lining manner.