The invention relates to a centrifuge (10) for automatic loading, having a drive shaft (44), which is driven in a rotatable manner about a rotor axis (42), having a rotor (46), which is releasably coupled for conjoint rotation to the drive shaft (44) and has mounts for containers for media to be centrifuged, having a housing (12) with lateral outer walls (14, 16, 18, 20) delimiting the centrifuge (10) and with a ceiling (22), wherein at least one outer wall (14) has a sideways directed side opening (28) for loading the rotor (46) as required, and having a safety vessel (50) with at least one partially enclosing protective wall (34), which is adapted at least to the shape of the adjacent outer wall (14) with side opening (28) such that said protective wall closes off the side opening (28).

A fluid supply apparatus for a centrifuge, which supplies a fluid to a centrifuge chamber of the centrifuge is provided. The fluid supply apparatus includes a nozzle unit configured to supply the fluid, a nozzle moving unit movable between an inside or an outside of the centrifuge, a nozzle receiving unit to supply the fluid to the centrifuge chamber by seating the nozzle moving unit, and a fixing unit coupled to the nozzle moving unit such that the nozzle moving unit is movable, and fixed to the centrifuge.

A fluid supply apparatus for a centrifuge, which supplies a fluid to a centrifuge chamber of the centrifuge is provided. The fluid supply apparatus includes a nozzle unit configured to supply the fluid, a nozzle moving unit movable between an inside or an outside of the centrifuge, a nozzle receiving unit to supply the fluid to the centrifuge chamber by seating the nozzle moving unit, and a fixing unit coupled to the nozzle moving unit such that the nozzle moving unit is movable, and fixed to the centrifuge.

A method of operating a centrifugal separator is provided. The method includes supplying a liquid mixture to be separated to the inlet of the centrifugal separator, separating the liquid mixture into at least one separated liquid component and a separated sludge component, discharging at least one separated liquid component from at least one liquid outlet of the centrifuge rotor, removing gas from a space surrounding a centrifuge rotor of the separator, to obtain a sub-atmospheric pressure in the space, and discharging a separated sludge component from at least one sludge outlet arranged at a periphery of the centrifuge rotor to the space which is delimited by a frame, wherein the discharging is performed when the sub-atmospheric pressure in the space surrounding the centrifuge rotor is within a preset pressure interval ΔP.

A method of operating a centrifugal separator is provided. The method includes supplying a liquid mixture to be separated to the inlet of the centrifugal separator, separating the liquid mixture into at least one separated liquid component and a separated sludge component, discharging at least one separated liquid component from at least one liquid outlet of the centrifuge rotor, removing gas from a space surrounding a centrifuge rotor of the separator, to obtain a sub-atmospheric pressure in the space, and discharging a separated sludge component from at least one sludge outlet arranged at a periphery of the centrifuge rotor to the space which is delimited by a frame, wherein the discharging is performed when the sub-atmospheric pressure in the space surrounding the centrifuge rotor is within a preset pressure interval ΔP.

A centrifugal piston according to an embodiment comprises: a piston body defining a path which extends from the front of the piston to the rear of the piston, and through which substances at the front of the piston can move to the rear of the piston; and a valve disposed on the path and configured to selectively open or block the path, wherein, during centrifugation in which centrifugal force acts on the piston, the substances at the front of the piston are centrifuged while the valve is blocking the path, and, when an external force is applied to the piston while the centrifugal force does not act on the piston, the valve moves freely relative to the piston body, and when the valve opens the path, at least a portion of the substances at the front of the piston can move to the rear of the piston.

A centrifugal piston according to an embodiment comprises: a piston body defining a path which extends from the front of the piston to the rear of the piston, and through which substances at the front of the piston can move to the rear of the piston; and a valve disposed on the path and configured to selectively open or block the path, wherein, during centrifugation in which centrifugal force acts on the piston, the substances at the front of the piston are centrifuged while the valve is blocking the path, and, when an external force is applied to the piston while the centrifugal force does not act on the piston, the valve moves freely relative to the piston body, and when the valve opens the path, at least a portion of the substances at the front of the piston can move to the rear of the piston.

The present invention relates to a platelet rich plasma (PRP) extracting device and extracting method using the same, and more particularly, to a platelet rich plasma (PRP) extracting device capable of quickly and effectively extracting the highly concentrated PRP from centrifuged blood by a simple manipulation.

The present invention relates to a platelet rich plasma (PRP) extracting device and extracting method using the same, and more particularly, to a platelet rich plasma (PRP) extracting device capable of quickly and effectively extracting the highly concentrated PRP from centrifuged blood by a simple manipulation.

A transfer container for a fluid includes a tube, the tube including a conical portion at one end, the tube defining an interior space and one or more fluid passages configured to allow flow of fluid into or out of the interior space of the tube. The transfer container also includes a connector configured to seal the end of the conical portion when the connector is joined only to the conical portion and a pressure control mechanism configured to increase or decrease a pressure in the interior space of the tube. The transfer container can be used in a method including connecting fluid lines to the fluid passages, adding a fluid including cryoprotectant and cells, centrifuging the transfer container, and then connecting the transfer container to a second fluid transfer container containing another fluid. This allows the sterile transfer of fluids and separation of cells from cryoprotectant.