Handling device for an apparatus for the additive manufacture of three-dimensional objects, which handling device is equipped to handle an additively manufactured three-dimensional object, comprising: a handling chamber, which comprises a handling chamber interior delimited by one or more handling chamber walls, wherein at least one handling chamber wall comprises an access opening allowing access, in particular for a user, into the handling chamber interior, wherein the at least one access opening is openable and closable via a thereto assigned sliding-door-like closure element, which is mounted such that it is slidingly movable in a vertical direction between an open setting, in which the sliding-door-like closure element opens up the at least one access opening, and a closed setting, in which the sliding-door-like closure element closes off the access opening, relative to the handling chamber wall comprising the access opening.

Handling device for an apparatus for the additive manufacture of three-dimensional objects, which handling device is equipped to handle an additively manufactured three-dimensional object, comprising: a handling chamber, which comprises a handling chamber interior delimited by one or more handling chamber walls, wherein at least one handling chamber wall comprises an access opening allowing access, in particular for a user, into the handling chamber interior, wherein the at least one access opening is openable and closable via a thereto assigned sliding-door-like closure element, which is mounted such that it is slidingly movable in a vertical direction between an open setting, in which the sliding-door-like closure element opens up the at least one access opening, and a closed setting, in which the sliding-door-like closure element closes off the access opening, relative to the handling chamber wall comprising the access opening.

A glove box has an enclosure having a glass window top and gloves mounted to the front wall. The enclosure can be tilted to so that one or other, or both, of the work piece and the window can be placed at an angle such as may facilitate processing. The glove box has an environmental control system to both to permit flushing with inert or other desired gases, and to permit heating or cooling. The workstand may have cooling passages as well. Controls are mounted inside the enclosure chamber to permit the operator to change working parameters without removing his or her hands from the gloves. A parameter status display may be located outside the enclosure. The window may be provided with a movable smoked glass filter for use during welding. The workstand may be independently adjustable for angle within the enclosure. The glove box has electrical and cooling service penetrations to permit use of a welding electrode.

A glove box has an enclosure having a glass window top and gloves mounted to the front wall. The enclosure can be tilted to so that one or other, or both, of the work piece and the window can be placed at an angle such as may facilitate processing. The glove box has an environmental control system to both to permit flushing with inert or other desired gases, and to permit heating or cooling. The workstand may have cooling passages as well. Controls are mounted inside the enclosure chamber to permit the operator to change working parameters without removing his or her hands from the gloves. A parameter status display may be located outside the enclosure. The window may be provided with a movable smoked glass filter for use during welding. The workstand may be independently adjustable for angle within the enclosure. The glove box has electrical and cooling service penetrations to permit use of a welding electrode.

A shielded containment cabinet device for use for the cleaning under high visibility and high protection for user, while using reduction flow pressurized water for cleaning of materials.

An apparatus for processing one or more products in need of closure. The apparatus comprises a vessel including an inlet for receiving the one or more products and an outlet for discharging the one or more products under sterile and/or pyrogen free conditions. A device is also adapted for applying the closure to the one or more products in the vessel, along with the optional filling and/or weighing of the products before or after applying the closure. Related apparatuses, systems, and methods are disclosed.

An apparatus for processing one or more products in need of closure. The apparatus comprises a vessel including an inlet for receiving the one or more products and an outlet for discharging the one or more products under sterile and/or pyrogen free conditions. A device is also adapted for applying the closure to the one or more products in the vessel, along with the optional filling and/or weighing of the products before or after applying the closure. Related apparatuses, systems, and methods are disclosed.

A cuff attachment for an isolator sleeve cuff, the cuff attachment comprising an annular band of substantially elastomeric material having an open first end and an open second end, the first end having a diameter which is wider than a diameter of the second end, the first end being adapted to be attachable to an isolator sleeve cuff, and the second end being adapted to releasably retain a plug therein. A plug for sealing the second end of the cuff attachment, the plug comprising a body sized and shaped to be releasably retained in the second end of the cuff attachment. An isolator sleeve system comprising the cuff attachment and the plug.

A cuff attachment for an isolator sleeve cuff, the cuff attachment comprising an annular band of substantially elastomeric material having an open first end and an open second end, the first end having a diameter which is wider than a diameter of the second end, the first end being adapted to be attachable to an isolator sleeve cuff, and the second end being adapted to releasably retain a plug therein. A plug for sealing the second end of the cuff attachment, the plug comprising a body sized and shaped to be releasably retained in the second end of the cuff attachment. An isolator sleeve system comprising the cuff attachment and the plug.

Disclosed is a method for manufacturing a leaktight assembly by providing a bag, a connection system including a connector adapted for mechanical connection to a complementary connector of a sterile chamber in order to establish sterile communication between the bag and the chamber, the connector including a portion for attachment to the bag, the connection system further including an overmolding molded over the attachment portion, the manufacturing method further including the steps of positioning the wall of the bag facing the overmolding at a first access opening of the bag, the attachment portion surrounding a space for passage between the bag and the chamber at the first access opening, and welding the wall of the bag onto the overmolding.