The invention relates to a workstation (1), a preparation station (2) and a method for manipulating an electron microscopy grid assembly (3). The workstation (1) comprises a first compartment (101), a first gas inlet (102) for generating an overpressure in the first compartment (101), a first glove (104) and a second glove (105), each being fixed in a respective opening (106, 107) of the workstation (1), wherein the first glove (104) and the second glove (105) are movable in the first compartment (101) to manipulate objects in the first compartment (101), wherein the workstation (1) comprises a port (109) for providing a transfer device (4) for an electron microscopy grid assembly (3) in the first compartment (101). The preparation station (2) comprises a coolant reservoir (201, 202), a first part (210) configured to hold a shuttle (6) for holding an electron microscopy grid assembly (3) in a fixed orientation, wherein the preparation station (2) is configured such that the first part (210) is submergable in the cryogenic coolant when the coolant reservoir (201, 202) contains the cryogenic coolant.

The disclosure provides a modular isolator apparatus. The apparatus comprises an isolator comprising a housing, having an opening therein, and an isolator coupling member disposed around the opening. The apparatus further comprises at least one functional unit comprising a functional unit coupling member configured to reversibly couple with the isolator coupling member, thereby reversibly coupling the functional unit and the isolator. The apparatus further comprises at least one sealing member, configured to create an airtight seal between the isolator and functional unit coupling members when they are coupled; and at least one locking member, configured to secure the functional unit to the isolator when the isolator and functional unit are coupled. The apparatus is characterised in that when the functional unit is not secured to the isolator it is removable therefrom.

The disclosure provides a modular isolator apparatus. The apparatus comprises an isolator comprising a housing, having an opening therein, and an isolator coupling member disposed around the opening. The apparatus further comprises at least one functional unit comprising a functional unit coupling member configured to reversibly couple with the isolator coupling member, thereby reversibly coupling the functional unit and the isolator. The apparatus further comprises at least one sealing member, configured to create an airtight seal between the isolator and functional unit coupling members when they are coupled; and at least one locking member, configured to secure the functional unit to the isolator when the isolator and functional unit are coupled. The apparatus is characterised in that when the functional unit is not secured to the isolator it is removable therefrom.

An assembly for transferring an element from or towards the inside of a closed contaminated enclosure having an opening. The transfer assembly includes a first door closing substantially sealingly the opening of the contaminated enclosure and a transfer box delimiting an enclosed space and having an opening closed by a second door configured to pivot towards the inside of the transfer box, the first door and the second door each having at least one coupling member configured to allow the coupling of the first door and of the second door and configured to allow the first door and the second door, coupled to one another, to pivot towards the inside of the transfer box.

An assembly for transferring an element from or towards the inside of a closed contaminated enclosure having an opening. The transfer assembly includes a first door closing substantially sealingly the opening of the contaminated enclosure and a transfer box delimiting an enclosed space and having an opening closed by a second door configured to pivot towards the inside of the transfer box, the first door and the second door each having at least one coupling member configured to allow the coupling of the first door and of the second door and configured to allow the first door and the second door, coupled to one another, to pivot towards the inside of the transfer box.

A workspace isolated from an exterior space by a partition, a glove provided to the partition so that an external surface thereof is exposed to the workspace and an internal surface thereof communicates with the exterior space, and a robot configured to insert an arm into the glove and perform a work in the workspace. The glove includes, at a tip-end part thereof, an operating part provided inside the glove, and a hand part provided so as to be exposed to the workspace.

A workspace isolated from an exterior space by a partition, a glove provided to the partition so that an external surface thereof is exposed to the workspace and an internal surface thereof communicates with the exterior space, and a robot configured to insert an arm into the glove and perform a work in the workspace. The glove includes, at a tip-end part thereof, an operating part provided inside the glove, and a hand part provided so as to be exposed to the workspace.

A system for validating a system for monitoring pharmaceutical operations includes at least one controller configured to perform a classification of an intervention captured by one or more image frames using a classification model, the classification model being trained with image frames of interventions assigned to at least two different classes. The at least one controller is also configured to assign a value to an individual feature of a feature set associated with the classification, the value corresponding to a contribution of the individual feature to the classification. In addition, the at least one controller is configured to generate a graphical representation of the values for the features contributing to the classification of the interventions.

A liquid transport method is disclosed for efficiently producing cell cultures. The liquid transport method of the present disclosure, which is in processing of cells, includes: a) a step in which a container holding a liquid is gripped by a gripping tool of a robot; and b) a step in which the liquid in the container is transported to a collection container by rotating the gripped container. In steps a) and b) the robot operates such as not to pass over a vertical line of an opening of the collection container.

A liquid transport method is disclosed for efficiently producing cell cultures. The liquid transport method of the present disclosure, which is in processing of cells, includes: a) a step in which a container holding a liquid is gripped by a gripping tool of a robot; and b) a step in which the liquid in the container is transported to a collection container by rotating the gripped container. In steps a) and b) the robot operates such as not to pass over a vertical line of an opening of the collection container.