By the ingestion of dosage forms containing sparingly water-soluble drug particles, it is not possible to deliver drug into the blood stream at high rates, because the drug dissolution rate, and the absorption rate, are limited by solubility. Herein, therefore, dosage forms comprising a slender, three-dimensional structural framework of sparingly-soluble drug dissolved in an excipient matrix comprising at least a water-soluble polymer carrier and an amphiphilic polymer are disclosed. Upon immersion in a physiological fluid, said fluid wets the structural framework, interdiffuses with it, and the amphiphilic polymer self-assembles as micelles, thereby enhancing drug solubility. Concomitantly, the framework erodes and rapidly releases drug molecules, thus enhancing drug concentration in the fluid and the drug delivery rate into the blood stream.

A thin ribbon spirally wound polymer conduit and method of forming, wherein a helical reinforcing bead is interposed adjacent overlapping layers of ribbon. Further, a method of continuously forming spirally wound conduit wherein a sacrificial layer, preferably having a different base polymer to that of the conduit, is first applied to the former before the conduit is formed overtop.

A head is disclosed for use with a continuous manufacturing system. The head may have a housing configured to receive a matrix and a continuous fiber, and a diverter located at an end of the housing. The diverter may be configured to divert radially outward a matrix-coated fiber. The head may also include a cutoff having an edge configured to press the matrix-coated fiber against the diverter.

A fire rated door includes a core, a first decorative panel and a second decorative panel. The core includes: (a) a gypsum-based fire resistant center panel having a bottom, a top, a first side, a second side, a first end and a second end, wherein the gypsum-based fire resistant center panel is made of a first gypsum-based fire resistant material, and (b) an extruded gypsum-based fire resistant border attached to the first side, the second side, the first end and the second end of the gypsum-based fire resistant center panel, wherein the extruded gypsum-based fire resistant border is made of a second gypsum-based fire resistant material having a higher density than the first gypsum-based fire resistant material. The first decorative panel is attached to the top of the gypsum-based fire resistant center panel and the extruded gypsum-based fire resistant border. The second decorative panel is attached to the bottom of the gypsum-based fire resistant center panel and the extruded gypsum-based fire resistant border.

A method for making an expanded, and optionally multi-component and/or colored PTFE monofilament is disclosed. The method includes forming a first paste by mixing a PTFE powder with a hydrocarbon solvent; forming an extrusion preform by pressing the first paste into a form; curing the extrusion preform by exposing the extrusion preform to a first temperature for a first time duration; forming a green monofilament by extruding the first paste through a die; expanding the green monofilament by exposing the green monofilament to a second temperature for a second time duration, the second time duration occurring after the first time duration; stretching the green monofilament substantially along a longitudinal axis of the green monofilament, the stretching the green monofilament occurring after the expanding the green monofilament; and sintering the green monofilament after the stretching the green monofilament.

A method of forming an oral product includes extruding a mixture, conveying the extruded mixture through one or more pairs of forming rollers, and cutting the extruded mixture into one or more oral products. The mixture can include polymer and at least one flavorant, sweetener, active ingredient, or combination thereof. The extruded mixture forms an extrudate having a predetermined cross-sectional shape. The one or more pairs of forming rollers abut to define a passage there between as each forming roller rotates. The passage has a cross-sectional shape corresponding to the predetermined cross-sectional shape. The method can be performed using a machine including an extruder, one or more pairs of forming rollers, and a cutting device.

A thin ribbon spirally wound polymer conduit and method of forming, wherein a helical reinforcing bead is interposed adjacent overlapping layers of ribbon. Further, a method of continuously forming spirally wound conduit wherein a sacrificial layer, preferably having a different base polymer to that of the conduit, is first applied to the former before the conduit is formed overtop.

A fracturing liquid delivery hose for recovery of shale oil and gas, and manufacturing method and co-extrusion mold thereof are provided. The method includes extrusion of a cover layer with a first adhesive layer and an inner lining layer with a second adhesive layer, formation of an enhancement layer, heating and pressurizing for bonding between the cover layer and the enhancement layer and between the inner lining layer and the enhancement layer, so that the formed fracturing liquid delivery hose has resistance at least to high pressure and chemical corrosion. The cover layer and the inner lining layer can use different types of materials.

A method that combines injection molding and extrusion is disclosed. First, a molten material is injected into a mold via an injection gate, the mold comprising a first portion and a second portion. Next, additional molten material is injected via the injection gate and pushed through an extrusion die located in the first portion of the mold and the second portion is separated from the first portion. In embodiments, the second portion is separated from the first portion before the additional material is injected. In other embodiments, the second portion is separated from the first portion simultaneously with the additional material being injected. The method may be used to produce longer and thinner parts with detailed features, such as catheters.

Described are polymer compositions that include a blend of copolyester polymers based on monomers that include on terephthalic acid (TPA), isophthalic acid (IPA) and 1,4-cyclohexanedimethanol (CHDM), wherein the blend includes a first copolyester that is semi-crystalline and a second copolyester that is amorphous; and films made from the polymer compositions useful for transparent high temperature conductive film applications.