An accommodating intraocular lens device is provided. The accommodating intraocular lens device comprises a base assembly and a power lens. The base assembly comprises a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity. The haptic may comprise an outer periphery, an inner surface and a height between a first edge and a second edge. The power lens is configured to fit within the central cavity. The power lens may comprise a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid. The first side of the power lens may be positioned at a predetermined distance from the first edge of the haptic.

The present disclosure generally relates to local therapies for the eye and, more particularly, to shaped controlled-release ocular implant devices, including methods for making and using such devices, for delivery of therapeutic agents to the eye. A molded two-layer ocular implant comprises a therapeutic agent for treatment or prevention of a disorder of the eye. The implant comprises a polymer layer and a silicone adhesive layer with a therapeutic agent interspersed therein and joined to the polymer layer. This implant is for placement in the sub-Tenon's space of the eye and provides sustained release of the therapeutic agent during the treatment or prevention of the disorder of the eye.

Embodiments of the invention described herein thus provide implants and methods for manufacturing an implant having an outer layer that is porous. The porous outer layer can help encourage tissue ingrowth into the implant. The porous outer layer may be positioned around a core structure this is solid or that has a hollow interior. The core structure may be spherical or any other appropriate shape for a medical implant.

In a method for the manufacture of a transmissive optical system from a blank, material ablation is achieved on the blank with an ablative laser, and the pulse duration of the ablative laser is less than 1 ns, and preferably lies between 3 fs and 100 fs, or between 100 fs and 10 ps.

An artificial eye lens having an integral optical part which has, viewed in the direction of an optical principal axis of the eye lens, a first optical side and an opposite, second optical side. The optical part is formed with a structure having birefringence, where the birefringent structure in the integral optical part is formed as a laser structure. A method for producing an artificial eye lens, where the birefringent structure is produced with a laser apparatus, and a pulsed laser beam having a pulse length of between 100 fs and 20 ps, a wavelength of between 320 nm and 1100 nm, a pulse repetition rate of between 1 kHz and 10 MHz, a focus diameter of less than 5 μm, and a power density of greater than 10.sup.6 W/cm.sup.2.

Described herein are methods of stereolithographically printing intraocular devices, in particular intraocular lenses, as well as stereolithographic compositions for use therein. The stereolithography composition may comprise: a photoinitiator; a mono-functional aryl acrylate monomer, wherein the acrylate group of the monofunctional aryl acrylate monomer is of the formula —0—(C═0)—CH═CH.sub.2; and a multifunctional methacrylate or acrylate cross-linker, wherein the monofunctional aryl acrylate monomer is present in the composition in a greater amount than the multifunctional methacrylate or acrylate cross-linker.

An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.

Provided is an intraocular lens having a novel structure with high utility which is easy to adapt to patients, and can improve quality of vision (QOV). In an intraocular lens, an optical characteristic is set rotationally symmetric around an optical axis, and a spherical aberration of a size corresponding to a coma aberration remaining in a patient's eye after extraction of a human lens of the eye is set.

The invention relates to an artificial eye lens comprising an optical part, which has a first optical side as viewed in a direction of an optical principal axis of the artificial eye lens and an opposite second optical side, wherein a structure with at least one depression is formed in a haptic arrangement of the artificial eye lens and/or in a surround that surrounds the optical part at least in certain areas and that differs from the haptic arrangement, wherein the structure is formed as a micro-perforation with a multiplicity of perforation zones and at least some perforation zones are filled at least in certain areas with at least one medicament for the purposes of producing a medicament repository. The invention also relates to a method for producing such an artificial eye lens.

A flexible intraocular lens including a reinforcing layer disposed on a sidewall of the intraocular lens is described. An example flexible intraocular lens includes a lens body and a reinforcing layer disposed thereon.