In one aspect, the invention provides an implantable device comprising a uniform mixture of components including degradable polymer, inorganic bone particulate either natural or synthetic, a drug, and a soluble microporagen. In some embodiments, the uniform mixture further includes a soluble polymer macroporagen. In some embodiments, the uniform mixture is coated with an immobilized outer porous layer comprising or consisting of synthetic or natural inorganic bone granules. In further aspects, the invention provides an implantable device comprising a composite core of degradable polymer, bone, and a drug, and a coating comprising or consisting of microporous bone overlayer covering the degradable composite core.

Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt an pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.

An apparatus for producing a web of fibrous material includes a roll having incisions with a depth of 0.01-2.00 mm, a width of 0.01-2.00 mm, and a pitch 0.01-10.00 mm, and rotated at a peripheral velocity v.sub.1 equal to the velocity of an upstream apparatus unit; a belt stretched between transmission rollers that advances at a velocity v.sub.2 less than v.sub.1, wherein v.sub.1/v.sub.2 lies between 1.05 and 1.40; a presser roller rotating at a peripheral velocity v.sub.2, associated with a presser system acting to press the belt against the metal roll with a pressure of 1-200 kg per centimeter; and a system that feeds a sheet of pliable fibrous material between the belt and the roll, the belt having a longitudinal elongation of no more than 5%, dimensional stability along its entire length, a thickness of 1-10 cm, and a hardness 24-70 Shore A.

To effectively dissipate heat discharged from various electronic or mechanical components, a high-performance ultra-thin heat dissipation sheet with high thermal conductivity and thermal emissivity by using a graphene/graphite nanoplate/carbon nanotube/nano-metal complex that forms a high-content 3D-structured complex that is stably dispersed, and a method of manufacturing the same, is provided. The method includes preparing a first heat dissipation film by sintering a composition for dissipating heat including a graphene/graphite nanoplate/carbon nanotube/nano-metal complex dispersion solution and a binder, and forming a second heat dissipation film on one surface or two opposite surfaces of the first heat dissipation film by using a graphene adhesive including the graphene/graphite nanoplate/carbon nanotube/nano-metal complex dispersion solution and an adhesive. A heat dissipation sheet according to the present invention may be utilized as a material with heat dissipation properties constituting a heat sink alone or with other materials with heat dissipation properties.

A spunbond method for producing non-woven fabric with deodorant feature from bamboo cellulose comprises following process steps. Prepare bamboo pulp mixture by blending bamboo pulp and coffee residue in proper mixing ratio. Put N-methylmorpholine N-oxide (NMMO) as solvent and 1, 3-phenylene-bis 2-oxazoline (BOX) as stabilizer into prepared bamboo pulp mixture to form dope. Via spunbond method, orderly perform extruding, spinning, quenching and pre-drawing process to convert the dope into bamboo filaments of fibrous strand. Orderly process coagulation, regeneration and post-draw to the bamboo filaments of fibrous strand to transform them into uniform fine bamboo cellulose filaments. Bond and lay these bamboo filaments of fibrous strand on a belt collector to form a webbed nonwoven. After post treatments of water rinsing, hydro-entangled needle punching and drying have been orderly applied, then a resultant nonwoven fabric in continuous filament of bamboo cellulose with deodorant feature is produced from the webbed nonwoven.

An extrudable biodegradable composition includes seaweed nanocellulose in the range of 1 to 3 wt %; a seaweed derivative in the range of 40-99 wt %; biodegradable polymer in the range of 0-30 wt %; plasticizer in the range of 0-25 wt %; and crosslinking agent in the range of 0-15 wt %. The extrudable biodegradable composition has a viscosity greater than approximately 500 cP and an extruded product made from the extrudable biodegradable composition has a controlled water soluble or water resistant property with a tensile strength of approximately 10 to 30 MPa.

An artificial structure for promoting microalgae growth includes a 3D-printed structure formed by positioning a printing surface on a movable stage of a 3D bioprinter in contact with a bio-ink that includes a mixture of a pre-polymer material with one or more of cellulose-derived nanocrystals (CNC), and microalgae cells. By projecting modulated light onto the printing surface while moving the stage, the bio-ink is progressively polymerized to define layers of an artificial coral structure with microalgae cells disposed thereon, where the artificial coral structure is configured to scatter light within the structure.

A resin composition includes a cellulose derivative in which at least one hydroxyl group is substituted with an acyl group, which has a weight average molecular weight of 10,000 to 75,000 and an average degree of substitution of the acyl group of 1.8 to 2.5, and which exhibits an amount (weight ratio) of an insoluble portion, when being dissolved in tetrahydrofuran (THF) at 25 C., of less than or equal to 5% by weight.

The present invention refers to a biomimetic minerizable 3D-printing ink, a method for the production of such a biomimetic minerizable 3D-printing ink, a method for the production of a biomineralized 3D-printed article, a biomineralized 3D-printed article as well as the use of a crystallization trigger which is an oligopeptide selected from the group comprising an oligopeptide of the HABP family and an oligopeptide of the P11-family for 3D printing.

A process for making poly alpha-1,3-glucan formate films by extrusion is disclosed. These films are translucent or transparent and can be used in packaging applications.