A rotary press comprising at least one pressing station having each of a vertically-adjustable upper and lower pressure roller, which are mounted by axes in the at least one pressing station. Cam-guided upper punches having punch heads are fed to the upper pressure roller by a control cam and a pull-up cam raises the upper punches to a highest point above a filling device. A vertically-adjustable safety cam is designed to be vertically adjustable in relation to the upper pressure roller. The rotary press may comprise a preliminary pressure cam, which is integrated in a guide block.

A rotary press comprising at least one pressing station having each of a vertically-adjustable upper and lower pressure roller, which are mounted by axes in the at least one pressing station. Cam-guided upper punches having punch heads are fed to the upper pressure roller by a control cam and a pull-up cam raises the upper punches to a highest point above a filling device. A vertically-adjustable safety cam is designed to be vertically adjustable in relation to the upper pressure roller. The rotary press may comprise a preliminary pressure cam, which is integrated in a guide block.

The purpose of present invention to provide a method for the production of an easy-to-take solid preparation, which is mainly characterized in that a coating processing for the easy-to-take property is simply performed by using a gelling agent in a dry process, without going through a wet condition, the easy-to-take solid preparation and the like. The present invention relates to a dry-process method for the production of an easy-to-take solid preparation wherein a compression-molded core is coated with a coating agent comprising a gelling agent that will show slipperiness when it is brought into contact with water, comprising directly applying only powder of the coating agent to a mortar inner surface, the bottom end surface of an upper-pestle, and the top end surface of a lower-pestle, and subsequently loading and integrally compression-molding a core-molding material; a powder composition for coating the solid preparation, which comprises a water-soluble polymer to be used in the aforementioned production method, and the like.

The purpose of present invention to provide a method for the production of an easy-to-take solid preparation, which is mainly characterized in that a coating processing for the easy-to-take property is simply performed by using a gelling agent in a dry process, without going through a wet condition, the easy-to-take solid preparation and the like. The present invention relates to a dry-process method for the production of an easy-to-take solid preparation wherein a compression-molded core is coated with a coating agent comprising a gelling agent that will show slipperiness when it is brought into contact with water, comprising directly applying only powder of the coating agent to a mortar inner surface, the bottom end surface of an upper-pestle, and the top end surface of a lower-pestle, and subsequently loading and integrally compression-molding a core-molding material; a powder composition for coating the solid preparation, which comprises a water-soluble polymer to be used in the aforementioned production method, and the like.

The purpose of present invention to provide a method for the production of an easy-to-take solid preparation, which is mainly characterized in that an outer layer-forming processing to provide an easy-to-take property is simply performed in a dry process without going through a wet condition so as to make the formed outer layer thicker; the easy-to-take solid preparation and the like. The present invention relates to a dry-process method for the production of an easy-to-take solid preparation wherein an inner core tablet is coated with a compression-molded outer layer-forming agent comprising a gelling agent that will show slipperiness when it is brought into contact with water, comprising loading separately or simultaneously the inner core tablet and powder of the outer layer-forming agent to a mortar inner surface, the bottom end surface of an upper-pestle, and the top end surface of a lower-pestle, and subsequently compression-molding them; a powder composition for coating a solid preparation for use in the above method, which comprises the water-soluble polymer and water-soluble sugar or sugar alcohol.

The purpose of present invention to provide a method for the production of an easy-to-take solid preparation, which is mainly characterized in that an outer layer-forming processing to provide an easy-to-take property is simply performed in a dry process without going through a wet condition so as to make the formed outer layer thicker; the easy-to-take solid preparation and the like. The present invention relates to a dry-process method for the production of an easy-to-take solid preparation wherein an inner core tablet is coated with a compression-molded outer layer-forming agent comprising a gelling agent that will show slipperiness when it is brought into contact with water, comprising loading separately or simultaneously the inner core tablet and powder of the outer layer-forming agent to a mortar inner surface, the bottom end surface of an upper-pestle, and the top end surface of a lower-pestle, and subsequently compression-molding them; a powder composition for coating a solid preparation for use in the above method, which comprises the water-soluble polymer and water-soluble sugar or sugar alcohol.

A sample encapsulation system includes a fixture, a base, a chamber having an inlet and a chamber housing. The housing has inner and outer housings. The chamber is mounted in the inner housing. The base, chamber and housing are affixed to one another and movable in the fixture. A cap has a first ram operably mounted thereto for engaging the chamber inlet. A second ram in the chamber opposite the inlet moves toward and away from the first ram. A heating assembly is positioned in the inner housing and a cooling assembly including a cooling jacket defined in part by the inner and outer housings includes a manifold. The chamber, housing and base are movable toward and away from the cap for engaging and disengaging the first ram with the chamber during and after the encapsulation cycle, respectively. The cooling system includes a vacuum breaker to self-drain following cooling.

A sample encapsulation system includes a fixture, a base, a chamber having an inlet and a chamber housing. The housing has inner and outer housings. The chamber is mounted in the inner housing. The base, chamber and housing are affixed to one another and movable in the fixture. A cap has a first ram operably mounted thereto for engaging the chamber inlet. A second ram in the chamber opposite the inlet moves toward and away from the first ram. A heating assembly is positioned in the inner housing and a cooling assembly including a cooling jacket defined in part by the inner and outer housings includes a manifold. The chamber, housing and base are movable toward and away from the cap for engaging and disengaging the first ram with the chamber during and after the encapsulation cycle, respectively. The cooling system includes a vacuum breaker to self-drain following cooling.

Various methods and apparatuses are presented for an ingestible capsule that includes a digital, ingestible sensor componentor ingestible sensorembedded into the capsule. The ingestible sensor component may be configured to activate upon coming into contact with conductive fluid, such as a body's stomach fluid. Once activated, the ingestible sensor component may be configured to perform various tasks, such as transmitting one or more signals and obtaining biometric data about the body that ingested the capsule.

Various methods and apparatuses are presented for an ingestible capsule that includes a digital, ingestible sensor componentor ingestible sensorembedded into the capsule. The ingestible sensor component may be configured to activate upon coming into contact with conductive fluid, such as a body's stomach fluid. Once activated, the ingestible sensor component may be configured to perform various tasks, such as transmitting one or more signals and obtaining biometric data about the body that ingested the capsule.