An integrated medical bite block is engaged by a user's teeth and installed into the user's mouth. The bite block includes a through passageway, an upper grove, and a lower grove. The through passageway is penetrating through the bite block. One end of the through passageway comprises an inlet opening, the other end comprises an oral opening. The oral opening is connected with the user's mouth. An upper surface of the bite block provides the upper grove configured for receiving one or more upper teeth (maxillary teeth) of the user, and a lower surface of the bite block provides a lower grove configured for receiving one or more lower teeth (mandibular teeth) of the user. One distance between the lower grove and the oral opening is greater than the other distance between the upper grove and the oral opening, thereby the invention serves to extend forward the mandible and reposition a malposition between the mandible and the maxilla of the user.

A device and method for example operating an in vivo imaging device wherein the illumination is operated at a certain rate or range of rates, and images are transmitted from the device.

Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and resuable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

A landmark estimating method estimates a position of a landmark that is a hole existing in an object and is a site through which an insertion portion penetrates, in an endoscope image obtained by picking up an image of the object by an endoscope with the insertion portion bent. The landmark estimating method includes estimating an axis of the insertion portion, estimating a boundary of the insertion portion and the object, and estimating the position of the landmark based on the axis and the boundary that are estimated.

A method for diagnosing a gastric lesion from endoscopic images is provided. The method comprises: acquiring a plurality of gastric lesion images; generating a dataset by linking the plurality of gastric lesion images with patient information; preprocessing the dataset in a way that is applicable to a deep learning algorithm; and building an artificial neural network by training the artificial neural network by using the preprocessed dataset as input and gastric lesion classification results as output.

An imaging capsule, including a radiation source; a collimator that blocks the emission of radiation from the radiation source except through two or more output columns; a detector paired to each output column configured to detect particles resulting from X-ray fluorescence and/or Compton backscattering in response to the particles emitted by the output columns; wherein the collimator is configured to rotate around an X axis to scan a partial or full inner circumference of a user's colon with radiation emitted from each output column; and wherein at least two of the two or more output columns are tilted by a distinct angle relative to a Y axis that is perpendicular to the X axis, to scan distinct positions along the user's colon and form images of a slice of the colon in parallel planes.

An imaging capsule, including a radiation source; a collimator that blocks the emission of radiation from the radiation source except through two or more output columns; a detector paired to each output column configured to detect particles resulting from X-ray fluorescence and/or Compton backscattering in response to the particles emitted by the output columns; wherein the collimator is configured to rotate around an X axis to scan a partial or full inner circumference of a user's colon with radiation emitted from each output column; and wherein at least two of the two or more output columns are tilted by a distinct angle relative to a Y axis that is perpendicular to the X axis, to scan distinct positions along the user's colon and form images of a slice of the colon in parallel planes.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

An endoscopy system including a balloon-equipped endoscope including a balloon which is configured for slidable frictional engagement with an interior wall of a body passageway and axial stretching of the interior wall when inflated to a slidable frictional engagement pressure and displaced axially along the body passageway and a balloon inflation subsystem operative to selectably inflate the balloon to the slidable frictional engagement pressure.

A insertion apparatus includes a flexible tube, a detection section that detects state information of the tube, a calculation section that calculates, based on the state information, shape information of the tube, and an input section that inputs characteristic information of the tube. The apparatus also includes a calculation section that calculates, based on the characteristic information, an operation state of a distal end of the tube, an calculation section that calculates an insertion state of the tube at a specific point closer to a proximal end than the distal end, based on the shape information, characteristic information, and operation state, and a measurement section that measures an actual operation state of the tube at the specific point.