Systems and methods automatically locate optical surfaces of an eye and automatically generate surface models of the optical surfaces. A method includes OCT scanning of an eye. Returning portions of a sample beam are processed to locate a point on the optical surface and first locations on the optical surface within a first radial distance of the point. A first surface model of the optical surface is generated based on the location of the point and the first locations. Returning portions of the sample beam are processed so as to detect second locations on the optical surface beyond the first radial distance and within a second radial distance from the point. A second surface model of the optical surface is generated based on the location of the point on the optical surface and the first and second locations on the optical surface.

A method of processing functional OCT image data, acquired by an OCT scanner scanning a retina that is being repeatedly stimulated by a light stimulus, to obtain a response of the retina to the light stimulus, comprising: receiving OCT image data generated by the OCT scanner repeatedly scanning the retina over a time period, and a sequence of stimulus indicators each indicative of a stimulation of the retina by the light stimulus in a respective time interval of a sequence of time intervals spanning the time period; calculating, for each stimulus indicator, a product of the stimulus indicator and a respective windowed portion of the sequence of B-scans comprising a B-scan based on a portion of the OCT image data generated while the retina was being stimulated in accordance with the stimulus indicator; and combining the calculated products to generate the indication of the response.

Retinal diseases, such as age-related macular degeneration (AMD), are the leading cause of blindness in the elderly population. Since no known cures are currently present, it is crucial to diagnose the condition in its early stages so that disease progression is monitored. Systems and methods for detecting and mapping the mechanical elasticity of retinal layers in the posterior eye are disclosed herein. A system including confocal shear wave acoustic radiation force optical coherence elastography (SW-ARF-OCE) is provided, wherein an ultrasound transducer and an optical scan head are co-aligned to facilitate in-vivo study of the retina. In addition, an automatic segmentation algorithm is used to isolate tissue layers and analyze the shear wave propagation within the retinal tissue to estimate mechanical stress on the retina and detect early stages of retinal diseases based on the estimated mechanical stress.

An ophthalmologic apparatus, includes: a first concave mirror and a second concave mirror having a concave surface-shaped first reflective surface and a concave surface-shaped second reflective surface; an SLO optical system configured to project light from an SLO light source onto a subject's eye via the first concave mirror and the second concave mirror, and to detect returning light from the subject's eye; a first optical scanner configured to deflect the light from the SLO light source to guide the light to the first reflective surface; a second optical scanner configured to deflect light reflected by the first reflective surface to guide the light to the second reflective surface; an OCT optical system including a third optical scanner, and configured to split light from an OCT light source into measurement light and reference light, to project the measurement light deflected by the third optical scanner onto the subject's eye, and to detect interference light between returning light of the measurement light from the subject's eye and the reference light; an optical path coupling member disposed between the first optical scanner and the first concave mirror, and combining an optical path of the SLO optical system and an optical path of the OCT optical system; and a correction unit configured to correct detection result of the interference light detected by the OCT optical system or an image formed based on the detection result.

Provided are an apparatus and a computer-readable storage medium having stored therein a program that can determine keratoconus with a simple configuration so as to allow the apparatus and the program to be distributed widely and contribute to early diagnosis of keratoconus. In a keratometer as a keratoconus determination apparatus, a prediction model for keratoconus is stored in a memory. The prediction model is a logistic regression model in which three parameters that are a steep meridian refractive power, a flat meridian refractive power, and a value indicating whether or not a subject eye has a with-the-rule astigmatism, are independent variables, and a probability of keratoconus is a dependent variable. A control unit substitutes the three parameter values into the prediction model, to obtain a probability of keratoconus. When the probability is greater than a cutoff value, the subject eye is determined to be suspected of having keratoconus.

An ophthalmologic apparatus includes an optical scanner, an interference optical system, an intraocular distance calculator, an image correcting unit, and a controller. The optical scanner is disposed at an optically substantially conjugate position with a first site of a subject's eye. The interference optical system is configured to split light from a light source into reference light and measurement light, to project the measurement light onto the subject's eye via the optical scanner, and to detect interference light between returning light of the light from the subject's eye and the reference light via the optical scanner. The image forming unit is configured to form a tomographic image of the subject's eye corresponding a first traveling direction of the measurement light deflected by the optical scanner, based on a detection result of the interference light. The intraocular distance calculator is configured to obtain an intraocular distance between predetermined sites of the subject's eye based on the detection result of the interference light. The image correcting unit is configured to correct the tomographic image based on the intraocular distance. The controller is configured to control at least the optical scanner.

A system for measuring at least one parameter of an eye. The system includes a probe detachably arranged within a housing, wherein the probe is operable to impact a surface of the eye with a predefined impact attribute, at least one coil operable to maintain the probe within the housing, to release the probe towards the surface of the eye and to retract the probe into the housing, a probe vibration means operable to induce vibration to the probe, a measuring means for measuring a change in vibration of the probe upon impact on the surface of the eye and a controller configured to use the measured change in vibration of the probe to determine the at least one parameter of the eye.

An ophthalmic apparatus of an aspect example includes an image acquiring unit, a corneal shape estimating processor, and a first image correcting processor. The image acquiring unit is configured to acquire an anterior segment image constructed based on data collected from an anterior segment of a subject's eye by optical coherence tomography (OCT) scanning. The anterior segment image includes a missing part corresponding to a part of a cornea. The corneal shape estimating processor is configured to estimate a shape of the missing part of a cornea image by analyzing the anterior segment image acquired by the image acquiring unit. The first image correcting processor is configured to correct distortion of the anterior segment image based at least on the shape of the missing part estimated by the corneal shape estimating processor.

In the ophthalmic imaging apparatus of an aspect example, the first image collecting unit collects a series of Scheimpflug images by performing scanning of a three dimensional region of a subject's eye with slit light. The second image collecting unit collects a series of time series images by performing repetitive photography of the subject's eye in parallel with the scanning of the three dimensional region performed by the first image collecting unit. The first image analyzing unit analyzes the series of time series images to determine time series shifts of the slit light during the scanning of the three dimensional region performed by the first image collecting unit. The image interpolating unit performs interpolation of the series of Scheimpflug images based on the time series shifts of the slit light determined by the first image analyzing unit.

A contact lens according to an embodiment of the present disclosure includes a lens unit to be placed on an eyeball and a mesh-like or meandering linear communication electrode provided in all or a portion of the lens unit.