A contact lens according to an embodiment of the present disclosure includes a lens unit to be placed on an eyeball and a mesh-like or meandering linear communication electrode provided in all or a portion of the lens unit.

A method and a device for label-free all-optical neural regulation and imaging are provided. The method stimulates a neural activity through an infrared laser pulse, and acquires an optical scattered signal caused by the neural activity by optical coherence tomography (OCT) to realize label-free all-optical neural regulation and imaging. The method specifically includes: aiming an infrared laser at a target brain region, injecting a certain time series of laser pulses, synchronously scanning and imaging the target brain region by OCT, analyzing a relative change of an OCT scattered signal before and after laser stimulation, and acquiring a brain function signal based on OCT to realize synchronous neural regulation and imaging. The method and the device enable synchronous neural regulation and imaging without causing crosstalk between the regulation and imaging channels, and without the need for injection of a contrast agent or viral transfection.

System for customizing visual field (VF) tests uses a machine learning model (15) trained on retina images (12A, 12C, 12D), including optical coherence tomography (OCT), optical coherence tomography angiography (OCTA), fundus, and/or fluorescein angiography images. In operation, in preparation for administering a specific VF test (13) to a patient, a retina image of the patient is submitted to the present machine model, which responds by synthesizing a VF prediction for the patient. The synthesized VF may be used to optimize the specific VF test prior to administering it to the patient.

An ophthalmic apparatus includes an illumination optical system, an optical scanner, an imaging optical system, a controller, and an image forming unit. The illumination optical system is configured to generate slit-shaped illumination light. The optical scanner is configured to deflect the illumination light to guide the illumination light to a fundus of a subject's eye. The imaging optical system is configured to guide returning light of the illumination light from the fundus to an image sensor. The controller is configured to control the optical scanner. The image forming unit is configured to form an image of the fundus based on a light receiving result captured in an imaging target region on a light receiving surface of the image sensor. The image sensor is configured to capture the light receiving result in an opening region on the light receiving surface using a rolling shutter method, the opening region corresponding to an illumination region of the illumination light on the fundus, the illumination region being moved in a predetermined scan direction by the optical scanner. The controller is configured to control the optical scanner so that irradiation times of the returning light at a plurality of light receiving elements in the imaging target region are substantially equal.

A method for determining a calibration factor in Doppler flowmetry velocity measurements in the living eye includes imaging the eye with Doppler flowmetry and processing data to obtain blood velocity, volume, and flow maps using Doppler flowmetry formulas that provide velocity as a mean frequency expressed in Hz, and volume and flow in arbitrary units. A selected blood vessel is probed with Doppler OCT to measure the absolute velocity of blood at that location expressed in mm/s to determine a calibration factor used to convert the velocity measured with Doppler flowmetry expressed in Hz to velocity expressed in mm/s.

Methods and systems for predicting the post-operative effective lens position (ELP) of a prosthetic intraoccular lens (IOL) in cataract surgery using novel pre-operative measurement(s) of the natural lens curvatures.

In a corneal measurement system, an optical element focuses an excitation light to an area of corneal tissue at a selected depth. In response, a fluorescing agent applied to the cornea generates a fluorescence emission. An aperture of a pinhole structure selectively transmits the fluorescence emission from the area of corneal tissue at the selected depth. A detector captures the selected fluorescence emission transmitted by the aperture and communicates information relating to a measurement of the selected fluorescence emission captured by the detector. A controller receives the information from the detector and determines a measurement of the fluorescing agent in the area of corneal tissue at the selected depth. The system may include a scan mechanism that causes the optical element to scan the cornea at a plurality of depths, and the controller may determine a measurement of the fluorescing agent in the cornea as a function of depth.

In a corneal measurement system, an optical element focuses an excitation light to an area of corneal tissue at a selected depth. In response, a fluorescing agent applied to the cornea generates a fluorescence emission. An aperture of a pinhole structure selectively transmits the fluorescence emission from the area of corneal tissue at the selected depth. A detector captures the selected fluorescence emission transmitted by the aperture and communicates information relating to a measurement of the selected fluorescence emission captured by the detector. A controller receives the information from the detector and determines a measurement of the fluorescing agent in the area of corneal tissue at the selected depth. The system may include a scan mechanism that causes the optical element to scan the cornea at a plurality of depths, and the controller may determine a measurement of the fluorescing agent in the cornea as a function of depth.

A system for visualizing a three-dimensional target area of an object with a measuring device which determines a distance of a surgical instrument in a target area with respect to a predetermined structure in the target area, a display unit for representing the views, and a control unit. The control unit controls the display unit such that the display unit is in a first display mode when a determined distance is greater than a predetermined first limit value, and switches from the first display mode into a second display mode when the determined distance changes from being greater than a predetermined second limit value, which is smaller than or equal to the predetermined first limit value, to smaller than the predetermined second limit value.

A contact lens includes a contact lens body and a glucose detection sheet disposed on the contact lens body. The glucose detection sheet includes a glucose recognition layer, a photonic crystal array is provided in the glucose recognition layer, and the glucose recognition layer is configured to recognize glucose.