A radio frequency applicator, including a waveguide having a first interior surface comprising a first aperture, a second interior surface opposing the first interior surface, a third interior surface adjacent to the first and second interior surfaces, a fourth interior surface opposing the third interior surface, and a fifth interior surface perpendicular to the first, second, third, and fourth interior surfaces, an aperture antenna, a solid dielectric insert within the waveguide, the solid dielectric insert having a second aperture formed therethrough that is configured for alignment with the first aperture, an RF connector, configured to receive generated RF energy pulses, at least one planar-shaped shim, having a third aperture therethrough configured to align with the first and second apertures, and a radio frequency feed pin connected to the RF connector, disposed within the first, second, and third apertures and affixed to the second interior surface of the waveguide.

Method for measuring a parameter of interest in a target environment (2) by means of a non-invasive sensor (1) based on photoacoustic detection or photothermal detection, comprisescomprising: a) a sensor that comprises an adaptation module (14) is provided comprising a processor that implements an inverse modelling algorithm: b) the adaptation module chooses an initial model irradiation configuration: c) it determines, in a correspondence table, the optimal irradiation case: d) a light source irradiates the target environment according to the optimal irradiation case: e) a detection cell detects a signal: f) the processor of the adaptation module returns a current model configuration (CMmes) and an estimated value for the parameter of interest (Pest): g) the processor of the adaptation module evaluates the chosen model irradiation configuration, and only if this irradiation model configuration differs from the current model configuration: g1) it receives the current model configuration (CMmes).

A method and system for enhancing radio frequency energy delivery to a region of interest is disclosed. The method includes emitting with a radio frequency (RF) applicator comprising a waveguide and a feed probe, one or more RF energy pulses into the region of interest, detecting with an acoustic receiver, at least one multipolar acoustic pressure wave generated in the region of interest in response to the emitted one or more RF energy pulses and processing data of the at least one multipolar acoustic pressure wave to determine a peak-to-peak amplitude thereof, adjusting a direct-current between the waveguide and the feed probe to tune the RF applicator based on the determined peak-to-peak amplitude, and emitting with the tuned RF applicator, one or more RF energy pulses into the region of interest.

A radio frequency applicator, including a waveguide having a first interior surface comprising a first aperture, a second interior surface opposing the first interior surface, a third interior surface adjacent to the first and second interior surfaces, a fourth interior surface opposing the third interior surface, and a fifth interior surface perpendicular to the first, second, third, and fourth interior surfaces, an aperture antenna, a solid dielectric insert within the waveguide, the solid dielectric insert having a second aperture formed therethrough that is configured for alignment with the first aperture, an RF connector, configured to receive generated RF energy pulses, at least one planar-shaped shim, having a third aperture therethrough configured to align with the first and second apertures, and a radio frequency feed pin connected to the RF connector, disposed within the first, second, and third apertures and affixed to the second interior surface of the waveguide.

The present embodiments relate generally to medical care and more particularly to a new imaging modality referred to herein as electroacoustic tomography (EAT) that not only depicts electrical field energy distribution in real time, but also enables clear discrimination between IRE and RE zones in situ during the treatment. According to some aspects, EAT exploits the phenomenon that the amplitude of acoustic emission generated by an electric field is proportional to the electrical energy deposition in tissue. After detecting these acoustic waves with ultrasound transducers, an image of the electric field distribution can be reconstructed in real-time. This will allow real time monitoring the IRE and provides feedback control of the treatment. Some embodiments are directed to a novel EAT combined with ultrasound (EAT/US) guided IRE intervention that permits a) real time ultrasound image-guided needle placement, and b) intraoperational discrimination of IRE and RE zones during the treatment of cancer.

A pressurizing unit applies pressure around a measurement site of a measurement subject so as to suppress blood flow at the measurement site during a set pressurizing time. While the pressurizing unit is applying pressure around the measurement site, a detection unit detects a photoacoustic signal generated at the measurement site irradiated with a light beam. The detection unit detects a photoacoustic signal when a preset time has elapsed after the pressurizing unit started to apply pressure around the measurement site.

The system includes a memory that stores first and second trained models, and a processor. The processor acquires a captured image in which at least one energy device and at least one biological tissue are imaged. The processor detects a bounding box from the captured image by processing based on the first trained model and estimates the image recognition information from the captured image in the bounding box by processing based on the second trained model. The processor outputs an energy output adjustment instruction based on the estimated image recognition information to the generator. The generator controls the energy supply amount to the energy device based on the energy output adjustment instruction.

A method of imaging may include receiving a first signal from one or more array elements of a first type in a mixed transducer array, receiving a second signal from one or more array elements of a second type in the mixed transducer array, where at least one of the first type or the second type is a tunable optical resonator and selectively configured to operate in different quality factor modes, generating a first image from the first signal and a second image from the second signal, and combining the first image and the second image to generate a compound image.

The system includes a memory that stores first and second trained models, and a processor. The processor acquires a captured image in which at least one energy device and at least one biological tissue are imaged. The processor detects a bounding box from the captured image by processing based on the first trained model and estimates the image recognition information from the captured image in the bounding box by processing based on the second trained model. The processor outputs an energy output adjustment instruction based on the estimated image recognition information to the generator. The generator controls the energy supply amount to the energy device based on the energy output adjustment instruction.

Real-time surgical imaging techniques with an energy transmissive surgical bed top having energy delivery/receiving systems above and below the bed top surface.