Embodiments described herein generally relate to: sensing and/or authentication using luminescence imaging; diagnostic assays, systems, and related methods; temporal thermal sensing and related methods; and/or to emissive species, such as those excitable by white light, and related systems and methods.

A medical treatment device is configured to be used during a treatment session at a first location and includes a medical treatment component configured to perform at least one of hemodialysis, hemofiltration, and peritoneal dialysis on a patient during the treatment session at the first location. The device also includes a monitoring system configured to receive data from one or more sensors connected to the monitoring system, and to confirm a presence of an authorized helper at the first location. A user interface permits an operator to control functions of the medical treatment component and the monitoring system is configured to perform the presence confirmation automatically and at the predefined time intervals during the treatment session. The monitoring system is also configured to generate an alarm and to cause the medical treatment component to go into a failsafe operational mode.

A medical treatment device is configured to be used during a treatment session at a first location and includes a medical treatment component configured to perform at least one of hemodialysis, hemofiltration, and peritoneal dialysis on a patient during the treatment session at the first location. The device also includes a monitoring system configured to receive data from one or more sensors connected to the monitoring system, and to confirm a presence of an authorized helper at the first location. A user interface permits an operator to control functions of the medical treatment component and the monitoring system is configured to perform the presence confirmation automatically and at the predefined time intervals during the treatment session. The monitoring system is also configured to generate an alarm and to cause the medical treatment component to go into a failsafe operational mode.

Methods and kits for collecting and verifying a specimen and/or biological information from a person at a first location to be provided to a second location are provided with documentation of chain of custody in order to verify that the person from whom the specimens and data were obtained is the intended person. Methods include internet and/or video communication between the person and a human or software-based verification assistant, confirming identification of the person to the verification assistant through the video communication, obtaining one or more specimens from the person or one or more types of biological information of the person, wherein the obtaining may be recorded through the internet/video communication, and the use and recording of coded tamper-evident packaging to ensure chain of custody before, during and after the internet/video communication.

Methods and kits for collecting and verifying a specimen and/or biological information from a person at a first location to be provided to a second location are provided with documentation of chain of custody in order to verify that the person from whom the specimens and data were obtained is the intended person. Methods include internet and/or video communication between the person and a human or software-based verification assistant, confirming identification of the person to the verification assistant through the video communication, obtaining one or more specimens from the person or one or more types of biological information of the person, wherein the obtaining may be recorded through the internet/video communication, and the use and recording of coded tamper-evident packaging to ensure chain of custody before, during and after the internet/video communication.

Embodiments herein provide a method and system for continuously validating a user during an established authenticated session using Photoplethysmogram (PPG) and accelerometer data. State of the art approaches are mostly based on feature extraction and ML modelling for PPG based continuous session validation, while a template based approach in the art follows a complicated approach. The method disclosed herein utilizes less computation intensive template based approach to continuously validate the user across the session. The method comprises preprocessing a PPG data or PPG signal acquired from a wearable device worn by the user to identify segments of negligible motion. A first segment, after authentication using conventional authentication mechanism, serves as the initial reference. The chosen segments are then tested one by one with respect to the reference. If the templates in a segment match those of the reference, it is updated as the new reference, else a re-authentication is triggered.

Embodiments herein provide a method and system for continuously validating a user during an established authenticated session using Photoplethysmogram (PPG) and accelerometer data. State of the art approaches are mostly based on feature extraction and ML modelling for PPG based continuous session validation, while a template based approach in the art follows a complicated approach. The method disclosed herein utilizes less computation intensive template based approach to continuously validate the user across the session. The method comprises preprocessing a PPG data or PPG signal acquired from a wearable device worn by the user to identify segments of negligible motion. A first segment, after authentication using conventional authentication mechanism, serves as the initial reference. The chosen segments are then tested one by one with respect to the reference. If the templates in a segment match those of the reference, it is updated as the new reference, else a re-authentication is triggered.

A wearable medication adherence monitoring (MAM) device for wearing by a patient, including an operating unit (OU) which includes: a wireless communications unit (WCU); a processing unit (CPU); a memory unit; and one or a plurality of peripheral interface(s) with a plurality of input peripherals; and further includes the plurality of input peripherals and output peripherals in a MAM unit (MAMU) which includes: an interactive visual display unit (VDU) including a visual display (VD) and a VD patient interaction (PI) tool (VDTOOL); and an interactive audio platform (AP) including an audio output unit (SPK) and an audio PI tool (MIC; and one or a plurality of sensor unit(s) (SU(s)) including at least one biomarker sensor, and optionally at least one biometric sensor; included in one or a plurality of attachment units (AU) for wearing of the device on or about a body part of the patient.

A wearable medication adherence monitoring (MAM) device for wearing by a patient, including an operating unit (OU) which includes: a wireless communications unit (WCU); a processing unit (CPU); a memory unit; and one or a plurality of peripheral interface(s) with a plurality of input peripherals; and further includes the plurality of input peripherals and output peripherals in a MAM unit (MAMU) which includes: an interactive visual display unit (VDU) including a visual display (VD) and a VD patient interaction (PI) tool (VDTOOL); and an interactive audio platform (AP) including an audio output unit (SPK) and an audio PI tool (MIC; and one or a plurality of sensor unit(s) (SU(s)) including at least one biomarker sensor, and optionally at least one biometric sensor; included in one or a plurality of attachment units (AU) for wearing of the device on or about a body part of the patient.

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.