Provided is a blood measurement device capable of accurately estimating the amount of a component contained in blood by passing light beams for calculating the amount of the component contained in blood along the same optical axis. A blood measurement device 10 of the present invention includes a light emitting part 11 having a first light emitting part 111 and a second light emitting part 112, a light receiving part 19, an actuator 16, and a computation and control part 17 that estimates a glucose level and controls operation of the actuator 16. When applicating a first light beam from the first light emitting part 111 to a measurement site, the computation and control part 17 causes the actuator 16 to move a light emission point of the first light emitting part 111 onto an optical axis 22 defined to penetrate through the measurement site, and when applicating a second light beam from the second light emitting part 112 to the measurement site, the computation and control part 17 causes the actuator 16 to move a light emission point of the second light emitting part 112 onto the optical axis 22.

Integrated sensor and infusion devices are disclosed herein. The present technology includes, for example, an integrated sensor and infusion device for sensing physiological parameter(s) and delivering a medicament to a body of a user based at least in part on the sensed parameter(s). The device can comprise an insertion assembly comprising a carrier assembly comprising a cannula carrier, a trocar assembly removably coupled to the carrier assembly, and a drive assembly comprising a torsion spring coupled to the trocar assembly such that, when actuated, the torsion spring rotates to drive the trocar assembly and the carrier assembly axially downward to insert an infusion cannula and sensor electrode into a user's skin. The drive assembly can comprise a plurality of coupled drive wheels and/or a scissor assembly with multiple interacting links.

Exemplary embodiments may provide a user interface and logic for assisting a user in calculating a proper medicament bolus dosage. The user interface may be simple and easy to understand. The user interface may clearly specify needed inputs, such as a carbohydrates amount for a meal that is about to be ingested and the current glucose level reading for the user. Entered inputs may be displayed on the user interface. The user interface may depict key calculated values resulting from calculations that involve the inputs, including the total bolus dosage calculation. The user interface also may depict the values that contribute to the total bolus dosage calculation. Some of the input values, such as carbohydrates amount, may be prepopulated by the management device or medicament delivery device. The user interface may permit overriding of prepopulated input values.

Methods, apparatus, systems, and methods are described that relate to microneedle-assisted aptamer-based electrochemical sensing for label-free, continuous real-time monitoring of biomarkers in a biofluid. One example device for electrochemical monitoring of one or more analytes in a biofluid includes a substrate and at least two microneedles coupled to the substrate. Each microneedle in the at least two microneedles includes a protruded needle structure and an electrode probe structure. The electrode probe structure of a first microneedle in the at least two microneedles includes an aptamer sequence which is specific for a first analyte and the electrode probe structure of the first microneedle is operable as a working electrode for detection of the first analyte using a first electrochemical detection technique.

A medical capsule with a sensor device comprising a light emitting element and a light detecting element with the sensor device being adapted to detect the presence or non-presence of blood and/or Biliverdin based on the light absorption properties of blood and Biliverdin. The capsule is provided with a casing forming a gap at its outer surface. The light emitting element alternatively emits violet light of a wavelength of about 380-450 nm, green light of a wavelength of about 530-580 nm, and red light of a wavelength of about 620-750 nm, whereas the light detecting element generates a separate sensor signal associated with measured light intensities I.sub.violet, I.sub.green, and I.sub.red of at least each of the wavelength ranges of the light from the light emitting element. By evaluating a quotient I.sub.red/I.sub.green, false-positive detection of blood can be avoided. The present disclosure also relates to a calibration method for said medical capsule.

The present invention relates to a digital content-based method for providing therapeutics information, the method comprising: a first step of performing stimulation on a brain of a user to obtain fNIRS (functional near-infrared spectroscopy) data of the user; a second step of extracting a first brain activation area from a plurality of brain areas of the user using the obtained fNIRS data; a third step of determining a first brain state of the user, based on the first brain activation area; a fourth step of providing the user with a content determined corresponding to the first brain state determined in the third step under an XR (Extended Reality) environment; a fifth step in which the user performs a mission corresponding to the content; a sixth step of extracting a second brain activation area from the plurality of brain areas with reference to the fNIRS data of the user following performing the mission; and a seventh step of determining a second brain state of the user, based on the second brain activation area; an eighth step of determining information related to amelioration of the brain state of the user.

A system is provided for monitoring glucose in a host, including a continuous glucose sensor that produces a data stream indicative of a host's glucose concentration and an integrated receiver that receives the data stream from the continuous glucose sensor and calibrates the data stream using a single point glucose monitor that is integral with the integrated receiver. The integrated receiver obtains a glucose value from the single point glucose monitor, calibrates the sensor data stream received from the continuous glucose sensor, and displays one or both of the single point glucose measurement values and the calibrated continuous glucose sensor values on the user interface.

A system is provided that furnishes expert procedural guidance based upon patient-specific data gained from surgical instruments incorporating sensors on the instrument's working surface, one or more reference sensors placed about the patient, sensors implanted before, during or after the procedure, the patient's personal medical history, and patient status monitoring equipment. Embodiments include a system having a surgical instrument with a sensor for generating a signal indicative of a property of a subject tissue of the patient, which signal is converted into a current dataset and stored. A processor compares the current dataset with other previously stored datasets, and uses the comparison to assess a physical condition of the subject tissue and/or to guide a procedure being performed on the tissue.

Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation).

The present application provides a method and device for determining inner and outer sides of limbs, and relates to the field of wearable devices. The method comprises: acquiring first somatosensory information of a first side of a limb of a user, the first side being an inner side or an outer side of the limb; and determining whether the first side is the inner side of the limb according to the first somatosensory information and reference information. The method and device facilitate a device that the user wears to perform automatic setting according to an identification result, thereby enhancing user experience.