Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes utilizing at least one light source configured to strike a target area of a sample, utilizing at least one light filter positioned to receive light transmitted through the target area of the sample from the at least one light source, utilizing at least one light detector positioned to receive light from the at least one light source and filtered by the at least one light filter, and to generate an output signal, having a time dependent current, which is indicative of the power of light detected, receiving the output signal from the at least one light detector with a processor, calculating the attenuance attributable to blood with a ratio factor based on the received output signal, and determining a blood glucose level based on the calculated attenuance.

An implant (in particular a stent) includes a main structure and a sensor assembly for measuring a body parameter. The sensor assembly includes at least one electrical conductor and at least one capacitor which are connected in such a way that the conductor and the capacitor form at least one electrical resonant circuit. The electrical conductor is surrounded by an electrical insulation. The electrical conductor is in the form of a coil having at least one turn. The capacitor is in contact at least on one side with the surrounding environment and its capacitance changes depending on the body parameter that is to be determined.

An arrangement for operating a biosensor emitting radiation includes an excitation light source, which generates at least one excitation radiation for the biosensor; a coupling fiber, at the entry surface of which the excitation radiation is coupled in; an optical Y-coupler, including an excitation arm, which is connected to the exit surface of the coupling fiber, a detector arm, which is connected to an optical detector, and a sensor foot, which can be connected to the biosensor. The excitation arm has a conical shape. The radiation axis of the excitation arm includes an angle in the range of 5° to 70° with the main radiation axis of the detector arm. The diameter of the excitation arm at the connecting point to the detector arm is less than two thirds the diameter of the detector arm. An arrangement for determining the glucose content blood is also provided.

Described herein are devices and methods for continuous real time monitoring of kidney function. In various embodiments, a urine analysis device collects sensor data describing one or more properties of urine. The urine analysis device may be integrated with a catheter system to continuously generate sensor data in real time as the urine is collected by the catheter system. Sensor data collected by the urine analysis device may be analyzed by physicians to detect changes in a patients kidney function. If necessary, based on the sensor data, physicians may perform an intervention to improve a patients kidney function.

Improved assessment of brain injuries, and improved brain injury management, is achieved using a combination of impact-related data derived from instrumented mouthguard devices, human function performance testing, and biomarkers derived from biological fluid (such as saliva and/or blood). The human function performance testing may include brain function performance testing, and/or other forms of human function performance testing. This involves combining a data-driven understanding of a head impact event (based on data collected via an instrumented mouthguard device) with a data-driven understanding of human function performance following that head impact event. The biomarkers may include salivary mRNA and/or ncRNA, and/or blood proteins (for example via a FDA-approved Brain Trauma Indicator test).

An apparatus device may include a bio-impedance sensor configured to take a bio-impedance measurement from a body of an individual, an optical sensor configured to take an optical measurement from the body of the individual, and a processing device configured to receive a first bio-impedance measurement from the bio-impedance sensor taken during a first period of time and a first optical measurement from the optical sensor taken during the first period of time, receive first location information of the individual during the first period of time, determine a first correlation between a physiological parameter and at least one of the first location, the first bio-impedance measurement, or the first optical measurement, and determine a first level of the physiological parameter based on the first correlation.

A system and method is provided for monitoring a biological substance in a bodily orifice. The system includes a wearable device configured to be worn in a bodily orifice. A biosensor is carried by the wearable device and is constructed and arranged to obtain raw data regarding a biological substance in the orifice. The biosensor includes a processor circuit to provide processed data from the raw data, and a transmitter to wirelessly transmit the processed data to a second device.

The present disclosure relates to optical methods and devices based on pulsate behavior of blood and optical absorption spectroscopy to measure the level of water and/or other substances or compounds, such as an alcohol or lipid, in the blood and the tissues surrounding blood vessels and arteries.

In some examples, a system includes a glucose sensor configured to generate a signal indicative of a blood glucose level of a patient, a medical device configured to deliver insulin to the patient, a peritoneal dialysis (PD) device, and control circuitry. The control circuitry is configured to control the PD device to deliver PD therapy to a patient during a PD cycle, determine a blood glucose level of the patient during the PD cycle based on a signal from the glucose sensor, determine that the blood glucose level is greater than or equal to a predetermined blood glucose level threshold, and control the medical device to deliver insulin to the patient in response to determining the blood glucose level is greater than or equal to the predetermined blood glucose level threshold.

Disclosed is an electronic skin sensor patch which is attached to a skin of a user and measures a bio signal, the electronic skin sensor patch including: a patch body including a frame which is formed with an opening and is made of a mechanical metamaterial; a sensing unit disposed on a first region of the patch body; a sensor system unit disposed on a second region of the patch body and configured to maintain a nonadherent state with the skin; and a wiring disposed along the frame of the patch body and configured to connect the sensing unit and the sensor system unit.