A device for collecting blood from a mammalian subject without using spontaneous capillary blood flow, the device including a collection cup subassembly having a cantilevered, concave slide for transporting blood down and away from a blood sampling location; a mid-body subassembly couplable to the collection cup assembly and including a housing having a proximal end and a distal end and defining a plenum space; and a plunger subassembly having a first end and a second end and including a plunger formed at the second end and one or more lancet elements attached to the plunger. Advantageously, the plunger and lancet elements are structured and arranged to translate through the mid-body subassembly and the collection cup subassembly to the blood sampling location.

An independent blood filter device depends on flow geometry to deliver blood serum or plasma free of detrimental levels of hemoglobin. It depends critically on an upstream flow rate or pressure differential limiting control element or device that limits the rate of change of pressure differential across the filter element. Pre-evacuated versions can be used to simultaneously draw blood from a living being and provide pressure differential across the filter element between an evacuated collector and a supply end open to atmosphere. A unit pressurized by hand motion employs the external shape of a partially filled blood collection tube as a piston to produce pressure in advance of the control element or device to create the pressure differential across the filter element to a collector vented to atmosphere. The control element or device is disclosed in numerous forms, including specially sized flow constrictions and compliant arrangements.

Various embodiments pertain to syringes having needles that automatically retract, and including syringe assemblies in which there is a means for damping any impact of the retracting needle, slowing the retracting needle, dissipating the kinetic energy of the needle, or the like, so as to lessen any jolt or disturbance experienced by the user.

An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

Transdermal microneedles continuous monitoring system is provided. The continuous system monitoring includes a substrate, a microneedle unit, a signal processing unit and a power supply unit. The microneedle unit at least comprises a first microneedle set used as a working electrode and a second microneedle set used as a reference electrode, the first and second microneedle sets arranging on the substrate. Each microneedle set comprises at least a microneedle. The first microneedle set comprises at least a sheet having a through hole on which a barbule forms at the edge. One of the sheets provides the through hole from which the barbules at the edge of the other sheets go through, and the barbules are disposed separately.

A syringe apparatus (10) is provided which comprises a syringe portion having a syringe (12) or holder (24) adapted to receive a syringe (12) therein, the syringe portion having a rear grip (38) for seating in or against a user's hand and a front grip (40) formed at or adjacent to a tip end (22) of the syringe portion; and a movable member (30) engagable with a plunger (16) of the said syringe (12), the movable member (30) having a finger grip (32) at or adjacent to a tip end (22) thereof, the movable member (30) being engaged with the syringe portion and configured to move relative to the rear grip when a user applies a force at the finger grip (32); wherein the front and rear grips (40, 38) are formed as lateral projections (40a, 40b; 38a, 38b) with respect to the movable member (30).

A bodily fluid collection system for collecting a bodily fluid from a patient, and a bodily fluid transfer system for transferring collected bodily fluid to a second collection device. A collection adapter has a connection port configured to securely connect with a hub of a syringe, and a collection interface opposite the connection port creates a fluid conduit to the barrel via the connection port and an inlet of the hub. A proximal adapter is connected to a proximal end of the fluid channel from the patient, and configured to removably interact with the collection interface of the collection adapter to connect the proximal end of the fluid channel to the barrel via the fluid conduit and inlet to the barrel to allow conveyance into the barrel of the at least some of the sampling portion of the sample of bodily fluid. The proximal adapter can be removed to allow access to any bodily fluid collected by the syringe.

The present invention relates to a separable cassette for measuring glycated hemoglobin. It is easy to use the separable cassette for measuring glycated hemoglobin of the present invention since a reagent is sequentially leaked during the rotation thereof. In addition, there is no need to shake the reagent beforehand, as the reagent without residual reagent is fully discharged by the rotation. Therefore, the measurement result is accurate because an error between the amount of the reagent used and the amount of sample blood is small.

The present invention relates to a separable cassette for measuring glycated hemoglobin. It is easy to use the separable cassette for measuring glycated hemoglobin of the present invention since a reagent is sequentially leaked during the rotation thereof. In addition, there is no need to shake the reagent beforehand, as the reagent without residual reagent is fully discharged by the rotation. Therefore, the measurement result is accurate because an error between the amount of the reagent used and the amount of sample blood is small.

An apparatus includes a hypodermic needle, a blood vessel dilator connected to the hypodermic needle, and an actuator connected to the blood vessel dilator in such a way that the actuator expands the blood vessel dilator. The blood vessel dilator helps mitigate blood vessel collapse.