Device for the in-vivo and/or in-vitro enrichment of target structures in a sample liquid, including at least one functional portion, which is provided with receptors for enriching the target structures. In order to improve the enrichment of the target structures in the sample liquid, it is provided according to the invention that the functional portion has a helical shape, which is produced by twisting a symmetrical starting cross section about a twisting axis. The invention likewise discloses a method for producing this device.

The present invention generally relates to collecting, determining and/or transmitting information associated with the process of receiving bodily fluid through a device opening and/or delivering substances to a subject. In one aspect, the device includes an information collecting portion and a fluid receiving portion. In another aspect, the two portions are constructed and designed to attach to one another. In one embodiment, actuation of one of the portions causes the other portion to actuate. Methods of time keeping and information transmission are also discussed.

The present disclosure relates generally to devices, systems, and methods for diagnosis and treatment via laser-treated skin and, more particularly, to devices, systems, and methods for inducing leakage or rupture of one or more blood vessels comprising the dermis for various diagnostic and therapeutic applications. Other aspects of the present disclosure can include methods for detecting one or more target analytes in a dermis of a subject, methods for facilitating skin-to-blood delivery of agent in a subject, and methods for collecting a fluid sample from the dermis of a subject.

A secure specimen sample bottle includes a base container for receiving a specimen. The base container has a plurality of locking protrusions formed along an inner surface of the base receptacle. A bottle includes a lock ring that has an upright spire structure that has a closed top end and the opposing open bottom end including a plurality of flexible fins that are configured to interlockingly mate with the locking protrusions so as to prevent removal of the lock ring relative to the base container upon engagement of the flexible fins to the locking protrusions. A removable cap is coupled to the lock ring.

A medical device configured as a tube holder for use in collecting bodily fluids, especially for use as a blood collection tube holder, the device embodying two coaxially alignable needles, the first needle being a forwardly facing fluid collection needle and the second needle being a rearwardly facing fluid discharge needle. The first and second needles are satisfactorily supported by a frontal attachment and body, respectively, that are disposed in relative sliding engagement along an interface that is transverse to the first and second needle and that extends at least from the second needle to an opening into a needle retraction chamber that projects rearwardly from the body.

Implementations of a capillary tube syringe are provided. In some implementations, a capillary tube syringe comprises an elongated hollow outer tube having a proximal end and a distal end and a needle extending from the first end of the outer tube outside the outer tube and extending inside the outer tube. In some implementations, an elongated hollow capillary tube having a proximal end and a distal end extend along the inside of the outer tube. In some implementations, a normally compressed spring is operatively connected to the needle. In some implementations, the spring is configured to expand when activated to retract the needle inside the elongated hollow tube. In some implementations, the capillary tube diameter is less than or equal to 0.865 inches.

A medical device configured as a blood collection tube holder, the device having a body with two spaced-apart, oppositely facing, coaxially aligned needles including a forwardly facing venipuncture needle and a rearwardly facing fluid discharge needle, the two needles being held by first and second needle holders separated by a compressible fluid seal defining part of a fluid path between the two needles and the two needle holders. The body also includes a discharge needle displacement member that is manually repositioned following removal of the last blood tube holder so that the discharge needle displacement member contacts the second needle holder and displaces the second needle holder and the fluid discharge needle laterally inside the body to initiate retraction of the venipuncture needle into a rearwardly projecting needle retraction chamber.

The invention is a bodily fluids sample collection device comprising a planar elastic elongated frame member and has frame sides concurrently angling inward to a cup securing region, thereby having an increasingly narrowing frame width to a semi-circular cup holding portion, adapted to securely receive a bodily fluids sample cup disposed in an upright position for receiving a bodily fluids sample from a patient, and flexibly adapted for easy placement and release of the bodily fluids sample cup. The toilet bowl or the toilet seat freely supports the device, and handles enables the patient to grasp the device without touching the toilet seat or the toilet bowl, and away from the sample cup of differing sizes. The device may have a collection handle, enabling the patient to grasp the device away from the bodily fluids sample cup.

The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.

A shieldable needle device including a drive member is disclosed. The drive member is extendable between a biased position and an extended position for moving a tip guard from an first position to a second position in which the tip guard shields a distal end of the needle cannula. The shieldable needle device includes a pair of wings extending laterally from opposing sides of the hub that are movable between a laterally extending position and a dorsal position. With the wings in the dorsal position, the wings retain the drive member in the biased position thereby maintaining the tip guard in the first position. Movement of the wings from the dorsal position to the laterally extending position releases retainment of the drive member. A second drive member may be included.