The present invention relates to methods and apparatuses for estimating the status of a bladder, especially with respect to the likelihood of an imminent voiding of the bladder. The apparatuses carry out computer-implemented methods of estimating a bladder status employing a bladder monitor which collects bladder data (e.g. using ultrasound) and transmits the bladder data to a data processor for algorithmic conversion to a bladder status. Such algorithms may be trained and tuned to a particular person's bladder. Having established a bladder status based on otherwise esoteric bladder data, the data processor may then trigger an alert signal where the bladder status meets particular criteria indicating an imminent voiding event. Such a trigger signal may be used to alert a nocturnal enuresis patient to an impending void so that they can be awoken before any bedwetting occurs.

A method of assessment of renal function by monitoring a time-varying fluorescence signal emitted from a fluorescent agent from within a diffuse reflecting medium with time-varying optical properties is provided that includes using a renal monitoring system comprising at least one light source, at least one light detector, at least one optical filter, and at least one controller to provide a measurement data set comprising a plurality of measurement entries, each measurement data entry comprising at least two measurements obtained at one data acquisition time from a patient before and after administration of the fluorescent agent.

In a microrunner structure, there are provided with components for a cleaning procedure required to conduct electrochemical sensing when a biosensor is activated for sensing; and a urine signal detection device that is a SoC (System on a Chip), which has a wireless transceiving circuit for receiving a urine measurement method and channel information transmitted from an intelligent device, and in turn, outputting a stimulus signal to trigger a biosensor or a non-biosensor in a multi-channel structure to conduct urine sense processing for a sensing area, as well as transmitting detection processing for a concentration of urine substances from the electrochemical sensing to the intelligent device through the wireless transceiving circuit to assess a risk index between a heart disease or diabetes and a kidney disease.

Disclosed herein is a urinary output monitoring system. The system can include a urinary output monitoring device having a device body with a front panel and a back panel, and a fluid collection bag attachment configured to be detachably coupled to the front panel and to secure a fluid collection bag. The system can further include a load cell configured to determine a load placed upon the fluid collection bag attachment. The load cell can be in communication with a console. An attachment system can be configured to couple the urinary output monitoring system to a securing surface, for example to the back panel, and can have two or more contact points coupled to one or more rails defining a longitudinal axis, the contact points defining a lateral axis and configured to longitudinally move along the rails.

Disclosed herein is an automated urinary output monitoring system including urine collection assembly that includes a first drainage tube coupled between a urinary catheter and an interim container, and a second drainage coupled between the interim container and a final container. A scale measures the weight of urine collected in the final container and a display depicts the volume of urine collected in the final container. A vacuum pump can be coupled with the final container to draw urine from the interim container into the final container, and an air vent can isolate the patient from the vacuum within the final container. The system can be configured to wirelessly transmit urine volume data to an external computing device. A gyroscope can be coupled with the scale to determine the orientation of the scale. Logic of the system can calculate urine volume and correlate with the time of day.

The present disclosure relates to systems and methods for determining the renal glomerular filtration rate or assessing the renal function in a patient in need thereof. The system includes a computing device, a power supply, one or more sensors, and at least one tracer agent that fluoresces when exposed to electromagnetic radiation. The electromagnetic radiation is detected using the sensors, and the rate in which the fluorescence decreases in the patient is used to calculate the renal glomerular filtration rate in the patient.

The present invention relates to a method for determining an organ function in a subject, comprising the steps of: providing a first concentration-time curve obtained by transcutaneously measuring in a body fluid at a first position background fluorescence in at least one first time point and fluorescence of an indicator compound in at least a second, a third, a fourth, a fifth, and a sixth time point; providing a second concentration curve obtained by transcutaneously measuring in a body fluid at a second position background fluorescence in at least one seventh time point and fluorescence of an indicator compound in at least a eighth, a ninth, a tenth, an eleventh, and a twelfth time point; fitting the first and the second concentration curve into a kinetic model representing at least four diffusion compartments; and thereby determining an organ function in a subject. The invention further relates to a device for determining an organ function according to the method of the present invention, said device comprising a first sensor for transcutaneously measuring fluorescence of an indicator at a first position, a second sensor for transcutaneously measuring fluorescence of an indicator at a second position; and a data processing unit for fitting the values obtained by the sensors into a kinetic model of one of the preceding claims. The present invention also relates to a kit comprising a device of the present invention and an indicator compound, as well as to a computer or computer network comprising at least one processor, wherein the computer or computer network is adapted to perform the method according to the present invention.

Offset illumination using multiple emitters in a fluorescence imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The emitter comprises a first emitter and a second emitter for emitting different wavelengths of electromagnetic radiation. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of a hyperspectral emission, a fluorescence emission, and/or a laser mapping pattern.

A toilet for animal, including: an upper container having a plurality of holes formed on a bottom portion, the plurality of holes penetrating in an up-down direction; a lower container that includes a receiving section receiving excrement that has passed through the plurality of holes, gravity of the upper container not acting on the lower container; and an output unit that outputs a signal changing according to an amount of the excrement received by the receiving section.

A printed circuit board device includes: a first capacitive sensor configured to measure a first capacitance within a contained volume having known dimensions, wherein the first capacitance changes as a substance is received into the contained volume; a second capacitive sensor having a plurality of trigger points at a plurality of corresponding known heights within the contained volume, the second capacitive sensor configured to detect when the substance received into the contained volume has reached each of the corresponding known heights within the contained volume; and wherein at least one of a level of the substance within the contained volume, a volume of the substance within the contained volume, or a flow rate of the substance into the contained volume is determined based on data from the first capacitive sensor and the second capacitive sensor.