Data analysis is combined with physiological data to provide indications of the health of bodily systems both acute and chronic time frames. The results can confirm the uniqueness of bio-metric security. It can also enhance both sport safety, rehab and fitness goals. The compared change(s) pattern can help for remote/self health monitor as well as wellness tracking.

The present invention relates generally and specifically to combining biological sensors with external machines using machine learning to form computerized representations that can control effectors to deliver therapy or enhance performance.

A system and method of treating a sleep disorder, including: detecting signals associated with at least one symptom or sign of the sleep disorder at one or more sensors; processing the signals to create a symbolic representation of the sleep disorder, wherein the symbolic representation indicates a relationship of the signals to the sleep disorder empirically and not based on physiologic mapping of the signals to the sleep disorder; and stimulating a region of a human body to alter the symbolic representation between detected signals and the sleep disorder, wherein the symbolic representation as altered indicates treatment of the sleep disorder.

A device and method for controlling a level of ventilatory assist applied to a patient by a mechanical ventilator measures, during patient's assisted breath, an inspiratory volume V.sub.assist produced by both the patient and the mechanical ventilator, an inspiratory volume V.sub.vent contributed by the mechanical ventilator, and an inspiratory assist pressure P.sub.vent produced by the mechanical ventilator. A first relation between pressure P.sub.vent and volume V.sub.assist and a second relation between pressure P.sub.vent and volume V.sub.vent are calculated. Using the first and second relations, a ratio is determined between pressure P.sub.vent at volume V.sub.vent and pressure P.sub.vent at volume V.sub.assist, with volume V.sub.vent equal to volume V.sub.assist, for a plurality of volumes V.sub.vent and V.sub.assist. Values of P.sub.vent are multiplied by the corresponding calculated ratios to calculate a third relation between a predicted inspiratory pressure P.sub.pred and volume V.sub.assist. The mechanical ventilator is responsive to the third relation to control the level of ventilatory assist.

An Implantable Pulse Generator (IPG) is disclosed that is capable of sensing a degree to which recruited neurons in a patient's tissue are firing synchronously, and of modifying a stimulation program to promote desynchronicity and to reduce paresthesia. An evoked compound action potential (ECAP) of the recruited neurons is sensed as a measure of synchronicity by at least one non-active electrode. An ECAP algorithm operable in the IPG assesses the shape of the ECAP and determines one or more ECAP shape parameters that indicate whether the recruited neurons are firing synchronously or desynchronously. If the shape parameters indicate significant synchronicity, the ECAP algorithm can adjust the stimulation program to promote desynchronous firing.

A lateral retractor system for forming a pathway to a patient's intervertebral disc space includes a single dilator and a retractable dual-tapered-blade assembly. The dilator may feature a narrow rectangular body for insertion at an insertion orientation parallel to the fibers of the patient's psoas muscle, at an approximate 45-degree angle to the patient's spine. The retractable dual-tapered-blade assembly consists of only two blade subassemblies, each having a blade bordered by adjustable wings, along with built-in lighting and video capabilities. The dual-tapered-blade assembly may be passed over the single dilator at the insertion orientation and rotated approximately 45-50 degrees to a final rotated orientation parallel to the intervertebral disc space before the two blade subassemblies are retracted away from one another to create the surgical pathway, while simultaneously and continuously assessing for encroachment upon one or more nerve structures within 360-degrees of the instrument. Other embodiments are also disclosed.

System, methods, and other embodiments described herein relate to mitigating effects of motion sickness on a passenger in a vehicle. In one embodiment, a method includes analyzing sensor data about the passenger to produce a passenger state that characterizes a current physical condition of the passenger while riding in the vehicle. The method includes determining whether the passenger state correlates with symptoms of motion sickness in the passenger. The method includes controlling, in the vehicle, a vehicle component to adjust a current configuration relative to the passenger when the passenger state correlates with the symptoms.

At least partial function of a human limb is restored by surgically removing at least a portion of an injured or diseased human limb from a surgical site of an individual and transplanting a selected muscle into the remaining biological body of the individual, followed by contacting the transplanted selected muscle, or an associated nerve, with an electrode, to thereby control a device, such as a prosthetic limb, linked to the electrode. Simulating proprioceptive sensory feedback from a device includes mechanically linking at least one pair of agonist and antagonist muscles, wherein a nerve innervates each muscle, and supporting each pair with a support, whereby contraction of the agonist muscle of each pair will cause extension of the paired antagonist muscle. An electrode is implanted in a muscle of each pair and electrically connected to a motor controller of the device, thereby simulating proprioceptive sensory feedback from the device.

A method for determining a desired location at which to apply a neural therapy. An array of electrodes is positioned proximal to neural tissue. A stimulus is applied from the array which evokes a neural compound action potential response in the neural tissue proximal to the array. A plurality of electrodes of the array simultaneously obtain respective measurements of the neural compound action potential response. From the measurements of the neural compound action potential response a desired location for a neural therapy is determined.

Example systems and techniques for denervation, for example, renal denervation. In some examples, a processor determines one or more tissue characteristics of tissue proximate a target nerve and a blood vessel. The processor may generate, based on the one or more tissue characteristics, an estimated volume of influence of denervation therapy delivered by a therapy delivery device disposed within the blood vessel. The processor may generate a graphical user interface including a graphical representation of the tissue proximate the target nerve and the blood vessel and a graphical representation of the estimated volume of influence.