A system and a method for testing a condition of a subject's nervous system using virtual reality technology are described. The method includes displaying a visual stimulus to the subject in a virtual reality environment. Eye and body movements of the subject are tracked as the subject focuses on the visual stimulus. The body movements may include head movements. Based on the eye and body movements, the condition of the subject's nervous system is evaluated and then results of the evaluation describing the subject's nervous system condition is reported to a user, such as a clinician, for further analysis thereof.

A neural event process, including receiving a neural response signal, decomposing the signal using at least one wavelet, differentiating phase data of the wavelets and the response signal to determine maxima and minima of the phase data and the signal, and processing the maxima and minima to determine peaks representing neural events.

An exemplary photodetector includes a SPAD and a capacitor. The capacitor is configured to be charged, while the SPAD is in a disarmed state, with a bias voltage by a voltage source. The capacitor is further configured to supply, when the SPAD is put in an armed state, the bias voltage to an output node of the SPAD such that a voltage across the SPAD is greater than a breakdown voltage of the SPAD.

An Implantable Pulse Generator (IPG) is disclosed that is capable of sensing a degree to which recruited neurons in a patient's tissue are firing synchronously, and of modifying a stimulation program to promote desynchronicity and to reduce paresthesia. An evoked compound action potential (ECAP) of the recruited neurons is sensed as a measure of synchronicity by at least one non-active electrode. An ECAP algorithm operable in the IPG assesses the shape of the ECAP and determines one or more ECAP shape parameters that indicate whether the recruited neurons are firing synchronously or desynchronously. If the shape parameters indicate significant synchronicity, the ECAP algorithm can adjust the stimulation program to promote desynchronous firing.

An Implantable Pulse Generator (IPG) is disclosed that is capable of sensing a degree to which recruited neurons in a patient's tissue are firing synchronously, and of modifying a stimulation program to promote desynchronicity and to reduce paresthesia. An evoked compound action potential (ECAP) of the recruited neurons is sensed as a measure of synchronicity by at least one non-active electrode. An ECAP algorithm operable in the IPG assesses the shape of the ECAP and determines one or more ECAP shape parameters that indicate whether the recruited neurons are firing synchronously or desynchronously. If the shape parameters indicate significant synchronicity, the ECAP algorithm can adjust the stimulation program to promote desynchronous firing.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

An image processing apparatus includes a processor programmed to obtain a first radiation image of a subject captured from a first direction, obtain a second radiation image of the subject captured from a second direction that intersects the first direction, and either correct one of the first radiation image and the second radiation image based on positional information of a device for capturing the one of the first radiation image and the second radiation image, or correct another one of the first radiation image and the second radiation image based on information on a position of a specific region of the subject obtained from the one of the first radiation image and the second radiation image.

An exemplary vascular neural interface device/configuration and method can be provided for at least one of stimulating or recording the nervous system. For example, a package can be provided which can be inserted within a blood vessel. The package can include at least one transducer, at least one electrode, and at least one integrated circuit. The at least one transducer can receive or transmit a wireless signal which is used to provide energy or communicate with the at least one integrated circuit to at least one of record or stimulate the nervous system using recording electronics or stimulating electronics.

The present invention provides a method and system for processing data from an event, such as a neurological event. When a neurological event occurs, a spike in a neural waveform is generated. The spike can be detected and used to determine information about the neurological event. The method uses data values from a resistive switching component capable of undergoing a resistive state change when a voltage is applied to it. The data values represent a sequence of resistive state changes of the resistive switching component which correspond to the neurological event. The method further comprises processing the received data values to identify a resistive state change corresponding to the neurological event and to obtain information about the neurological event. Thus, a method and system for processing neural spikes is provided.

A sensing and stimulation system includes a central hub, and a plurality of flexible arms extending from the central hub. Each of the arms includes at least one electrode and at least one sensor. Each of the arms is configured to perform sensing and stimulation including electrically stimulating biological material, and sensing biological responses and changes. The system includes a port configured to be alternatively connected to a remote control module for wireless operation of the system and a leaded connector for wired operation of the system.