Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

The present invention relates to devices, systems and methods for spectrally identifying tissues and guiding the introduction of a probe, needle, and medical instrument into a body structure. The probe can further be used for precise delivery of therapeutic agents to selected regions of the body.

Method, device and system for measuring a degree of torsion or bending of a joint. The method comprises the steps of attaching a sensor (56) to the limbs that are joined by the joint, measuring an output signal of the sensor during torsion or bending at the joint, and a final step of relating said output signal of the sensor to a degree of torsion or bending. The sensor comprises an electrically conductive loop (51), with loop parts that run from one limb to other and back in the loop, the area of said loop at least partially covering both limbs from one limb to the other. The limbs may be limbs of the human or animal body, for instance limbs at a knee. The sensor further comprises an output unit (57) for providing an output signal that is a measure for the inductance of the loop. Calibration data for the sensor may be determined by detecting the output signal of the sensor for a well defined degree of torsion or bending at said joint under static conditions and storing the calibration data.

Systems and methods are described for monitoring an individual and facilitating a motion regimen of the individual. In an aspect, a system includes, but is not limited to, a deformable substrate; a sensor assembly to generate sense signals based on detection of a movement of the body portion and a physiological parameter of the body portion during a motion regimen executed by the individual; a processor including circuitry configured to identify a pain state of the individual based on at least one of the movement or the physiological parameter, and to compare at least one of the pain state, the movement, or the physiological parameter to threshold target values; and a communicator configured to generate communication signals responsive to instruction by the processor, the communication signals associated with comparison between at least one of the pain state, the movement, or the physiological parameter to threshold target values.

Systems and methods are described for monitoring an individual subject and facilitating a motion regimen of the individual subject. In an aspect, a system includes, but is not limited to, a deformable substrate; a sensor assembly configured to generate one or more sense signals based on detection of at least one of a movement of the body portion or at least one physiological parameter of the body portion; a processor configured to receive the one or more sense signals, the processor including circuitry configured to identify a physiological state of the individual subject based on at least one of the movement of the body portion or the at least one physiological parameter of the body portion; and an effector operably coupled to the processor and configured to effect at least one predetermined motion of the body portion corresponding to a motion regimen responsive to control by the processor.

Systems and methods are described for monitoring, treating, and preventing a pain state of an individual. In an aspect, a system includes, but is not limited to, a deformable substrate; a sensor assembly coupled to the deformable substrate, the sensor assembly including a motion sensor and a physiological sensor, the sensor assembly configured to generate one or more sense signals based on detection of a movement of the body portion by the motion sensor and a physiological parameter of the body portion by the physiological sensor; a processor including circuitry configured to identify a physiological state of the individual subject based on at least one of the movement of the body portion or the physiological parameter; and an effector operably coupled to the processor and configured to affect the body portion responsive to control by the processor.

Systems and methods are described for monitoring, treating, and preventing a pain state of an individual. In an aspect, a system includes, but is not limited to, a deformable substrate; a sensor assembly coupled to the deformable substrate, the sensor assembly including a motion sensor and a physiological sensor, the sensor assembly configured to generate one or more sense signals based on detection of a movement of the body portion by the motion sensor and a physiological parameter of the body portion by the physiological sensor; a processor including circuitry configured to identify a physiological state of the individual subject based on at least one of the movement of the body portion or the physiological parameter; and an effector operably coupled to the processor and configured to affect the body portion responsive to control by the processor.

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

A system and method is disclosed herein for measuring bone slope or tilt of a prepared bone surface of the muscular-skeletal system. The system comprises a three-axis accelerometer for measuring position, rotation, and tilt. In one embodiment, the three-axis accelerometer can be housed in a prosthetic component that couples to a prepared bone surface. The system further includes a remote system for receiving, processing, and displaying quantitative measurements from one or more sensors. A bone is placed in extension. The three-axis accelerometer is referenced to a bone landmark of the bone when the bone is in extension. The three-axis accelerometer is then coupled to the prepared bone surface with the bone in extension. The slope or tilt of the bone surface is measured. In the example, the slope or tilt of the bone surface corresponds to at least one surface of the prosthetic component attached thereto.

A system and method for is provided for operation of an orthopedic system. The system includes a load sensor for converting an applied pressure associated with a force load on an anatomical joint, and an inertial sensing device configured to measure alignment. The inertial sensing device provides alignment measurement data to measure alignment. An ultrasonic transducer, MEMs microphone, electromagnets, optical elements, metallic objects or other transducers can be configured to convert or convey a physical movement to an electrical signal and support measurement of muscular-skeletal alignment. The load sensor can be used to measure load magnitude and position of load of an applied load by the muscular-skeletal system.